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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF846
Full Name:
Zinc finger protein 846
Alias:
Type:
Mass (Da):
60552
Number AA:
533
UniProt ID:
Q147U1
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T9
D
S
S
Q
H
L
V
T
F
E
D
V
A
V
D
Site 2
T18
E
D
V
A
V
D
F
T
Q
E
E
W
T
L
L
Site 3
Y33
D
Q
A
Q
R
D
L
Y
R
D
V
M
L
E
N
Site 4
S56
G
S
E
L
F
K
R
S
L
M
S
G
L
E
Q
Site 5
T69
E
Q
M
E
E
L
R
T
G
V
T
G
V
L
Q
Site 6
S87
L
Q
L
K
T
K
G
S
P
L
L
Q
D
I
S
Site 7
S94
S
P
L
L
Q
D
I
S
A
E
R
S
P
N
G
Site 8
S98
Q
D
I
S
A
E
R
S
P
N
G
V
Q
L
E
Site 9
S107
N
G
V
Q
L
E
R
S
N
T
A
E
K
L
Y
Site 10
T109
V
Q
L
E
R
S
N
T
A
E
K
L
Y
D
S
Site 11
Y114
S
N
T
A
E
K
L
Y
D
S
N
H
S
G
K
Site 12
S116
T
A
E
K
L
Y
D
S
N
H
S
G
K
V
F
Site 13
S142
T
H
I
G
E
K
T
S
E
D
N
Q
S
G
K
Site 14
S147
K
T
S
E
D
N
Q
S
G
K
A
L
R
K
N
Site 15
S158
L
R
K
N
F
P
H
S
F
Y
K
K
S
H
A
Site 16
S163
P
H
S
F
Y
K
K
S
H
A
E
G
K
M
P
Site 17
S212
R
T
F
L
N
Q
S
S
L
K
L
H
I
R
S
Site 18
S219
S
L
K
L
H
I
R
S
H
N
G
D
K
H
Y
Site 19
Y226
S
H
N
G
D
K
H
Y
V
C
K
E
C
G
K
Site 20
S236
K
E
C
G
K
A
F
S
N
S
S
H
L
I
G
Site 21
S238
C
G
K
A
F
S
N
S
S
H
L
I
G
H
G
Site 22
S239
G
K
A
F
S
N
S
S
H
L
I
G
H
G
R
Site 23
S249
I
G
H
G
R
I
H
S
G
E
K
P
Y
V
C
Site 24
Y254
I
H
S
G
E
K
P
Y
V
C
K
E
C
G
K
Site 25
S277
K
L
H
I
R
T
H
S
G
E
K
P
Y
K
C
Site 26
Y282
T
H
S
G
E
K
P
Y
K
C
K
E
C
G
K
Site 27
T292
K
E
C
G
K
A
F
T
H
S
S
Y
L
T
D
Site 28
S294
C
G
K
A
F
T
H
S
S
Y
L
T
D
H
T
Site 29
S295
G
K
A
F
T
H
S
S
Y
L
T
D
H
T
R
Site 30
Y296
K
A
F
T
H
S
S
Y
L
T
D
H
T
R
I
Site 31
T298
F
T
H
S
S
Y
L
T
D
H
T
R
I
H
S
Site 32
T301
S
S
Y
L
T
D
H
T
R
I
H
S
G
K
K
Site 33
Y310
I
H
S
G
K
K
P
Y
V
C
M
E
C
G
K
Site 34
T323
G
K
A
F
T
R
S
T
G
L
I
L
H
M
R
Site 35
T333
I
L
H
M
R
I
H
T
G
E
K
P
Y
E
C
Site 36
Y338
I
H
T
G
E
K
P
Y
E
C
K
E
C
G
K
Site 37
S351
G
K
A
F
I
H
S
S
Y
L
T
K
H
V
R
Site 38
Y352
K
A
F
I
H
S
S
Y
L
T
K
H
V
R
I
Site 39
T354
F
I
H
S
S
Y
L
T
K
H
V
R
I
H
S
Site 40
S361
T
K
H
V
R
I
H
S
G
E
K
L
Y
L
C
Site 41
Y366
I
H
S
G
E
K
L
Y
L
C
K
A
C
G
K
Site 42
S379
G
K
A
F
T
R
S
S
G
L
V
L
H
M
R
Site 43
T389
V
L
H
M
R
T
H
T
G
E
K
P
Y
E
C
Site 44
Y394
T
H
T
G
E
K
P
Y
E
C
K
E
C
G
K
Site 45
S406
C
G
K
A
F
N
N
S
S
M
L
S
Q
H
V
Site 46
S407
G
K
A
F
N
N
S
S
M
L
S
Q
H
V
R
Site 47
S410
F
N
N
S
S
M
L
S
Q
H
V
R
I
H
T
Site 48
T417
S
Q
H
V
R
I
H
T
G
E
K
P
Y
E
C
Site 49
T432
K
E
C
G
K
A
F
T
Q
S
S
G
L
S
T
Site 50
S434
C
G
K
A
F
T
Q
S
S
G
L
S
T
H
L
Site 51
S435
G
K
A
F
T
Q
S
S
G
L
S
T
H
L
R
Site 52
S438
F
T
Q
S
S
G
L
S
T
H
L
R
T
H
T
Site 53
T439
T
Q
S
S
G
L
S
T
H
L
R
T
H
T
G
Site 54
T445
S
T
H
L
R
T
H
T
G
E
K
A
C
E
C
Site 55
T473
N
M
H
M
R
T
H
T
G
E
K
P
Y
A
C
Site 56
Y478
T
H
T
G
E
K
P
Y
A
C
K
E
C
G
K
Site 57
T491
G
K
A
F
R
Y
S
T
Y
L
N
V
H
T
R
Site 58
Y492
K
A
F
R
Y
S
T
Y
L
N
V
H
T
R
T
Site 59
T501
N
V
H
T
R
T
H
T
G
A
K
P
Y
E
C
Site 60
Y506
T
H
T
G
A
K
P
Y
E
C
K
K
C
G
K
Site 61
T516
K
K
C
G
K
N
F
T
Q
S
S
A
L
A
K
Site 62
S519
G
K
N
F
T
Q
S
S
A
L
A
K
H
L
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation