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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NAT12
Full Name:
N-alpha-acetyltransferase 30, NatC catalytic subunit
Alias:
EC 2.3.1.-; MAK3; N-acetyltransferase 12
Type:
Enzyme - Acetyltransferase. Acetyltransferase family. MAK3 subfamily.
Mass (Da):
39320
Number AA:
362
UniProt ID:
Q147X3
International Prot ID:
IPI00219068
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0003824
GO:0008080
GO:0008415
PhosphoSite+
KinaseNET
Biological Process:
GO:0008152
GO:0008152
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
E
V
P
P
G
P
S
S
L
L
P
P
P
A
P
Site 2
S39
G
A
A
L
A
C
C
S
E
D
E
E
D
D
E
Site 3
S53
E
E
H
E
G
G
G
S
R
S
P
A
G
G
E
Site 4
S55
H
E
G
G
G
S
R
S
P
A
G
G
E
S
A
Site 5
T63
P
A
G
G
E
S
A
T
V
A
A
K
G
H
P
Site 6
S89
Q
Q
L
N
G
L
I
S
P
E
L
R
H
L
R
Site 7
S100
R
H
L
R
A
A
A
S
L
K
S
K
V
L
S
Site 8
T117
E
V
A
A
T
T
A
T
P
D
G
G
P
R
A
Site 9
T125
P
D
G
G
P
R
A
T
A
T
K
G
A
G
V
Site 10
T127
G
G
P
R
A
T
A
T
K
G
A
G
V
H
S
Site 11
S134
T
K
G
A
G
V
H
S
G
E
R
P
P
H
S
Site 12
S141
S
G
E
R
P
P
H
S
L
S
S
N
A
R
T
Site 13
S143
E
R
P
P
H
S
L
S
S
N
A
R
T
A
V
Site 14
S144
R
P
P
H
S
L
S
S
N
A
R
T
A
V
P
Site 15
T148
S
L
S
S
N
A
R
T
A
V
P
S
P
V
E
Site 16
S152
N
A
R
T
A
V
P
S
P
V
E
A
A
A
A
Site 17
S188
D
E
Q
V
R
L
L
S
S
S
L
T
A
D
C
Site 18
S190
Q
V
R
L
L
S
S
S
L
T
A
D
C
S
L
Site 19
T192
R
L
L
S
S
S
L
T
A
D
C
S
L
R
S
Site 20
S196
S
S
L
T
A
D
C
S
L
R
S
P
S
G
R
Site 21
S199
T
A
D
C
S
L
R
S
P
S
G
R
E
V
E
Site 22
S201
D
C
S
L
R
S
P
S
G
R
E
V
E
P
G
Site 23
T212
V
E
P
G
E
D
R
T
I
R
Y
V
R
Y
E
Site 24
Y215
G
E
D
R
T
I
R
Y
V
R
Y
E
S
E
L
Site 25
Y218
R
T
I
R
Y
V
R
Y
E
S
E
L
Q
M
P
Site 26
S220
I
R
Y
V
R
Y
E
S
E
L
Q
M
P
D
I
Site 27
T232
P
D
I
M
R
L
I
T
K
D
L
S
E
P
Y
Site 28
S236
R
L
I
T
K
D
L
S
E
P
Y
S
I
Y
T
Site 29
S240
K
D
L
S
E
P
Y
S
I
Y
T
Y
R
Y
F
Site 30
Y242
L
S
E
P
Y
S
I
Y
T
Y
R
Y
F
I
H
Site 31
Y283
K
K
M
F
R
R
G
Y
I
A
M
L
A
V
D
Site 32
Y293
M
L
A
V
D
S
K
Y
R
R
N
G
I
G
T
Site 33
T300
Y
R
R
N
G
I
G
T
N
L
V
K
K
A
I
Site 34
Y333
N
K
S
A
L
K
L
Y
E
N
L
G
F
V
R
Site 35
Y347
R
D
K
R
L
F
R
Y
Y
L
N
G
V
D
A
Site 36
Y348
D
K
R
L
F
R
Y
Y
L
N
G
V
D
A
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation