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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ARID5B
Full Name:
AT-rich interactive domain-containing protein 5B
Alias:
AT-rich interactive domain-containing protein 5B: ARID domain-containing protein 5B: Mrf1-like: Modulator recognition factor 2: ARID5B protein: AT-rich interactive domain-containing protein 5B: ARID domain-containing protein 5B: Mrf1-like: Modulator recognition factor 2
Type:
Mass (Da):
132375
Number AA:
1188
UniProt ID:
Q14865
International Prot ID:
IPI00399164
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0016564
PhosphoSite+
KinaseNET
Biological Process:
GO:0045892
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
N
S
L
Q
W
V
G
S
P
C
G
L
H
G
P
Site 2
T65
Q
L
L
W
E
E
R
T
S
R
Q
L
L
S
S
Site 3
S66
L
L
W
E
E
R
T
S
R
Q
L
L
S
S
S
Site 4
S71
R
T
S
R
Q
L
L
S
S
S
K
L
Y
F
L
Site 5
S72
T
S
R
Q
L
L
S
S
S
K
L
Y
F
L
P
Site 6
S73
S
R
Q
L
L
S
S
S
K
L
Y
F
L
P
E
Site 7
Y76
L
L
S
S
S
K
L
Y
F
L
P
E
D
T
P
Site 8
T82
L
Y
F
L
P
E
D
T
P
Q
G
R
N
S
D
Site 9
S88
D
T
P
Q
G
R
N
S
D
H
G
E
D
E
V
Site 10
Y146
Q
K
E
A
L
L
K
Y
R
Q
S
T
L
N
S
Site 11
S149
A
L
L
K
Y
R
Q
S
T
L
N
S
G
L
N
Site 12
T150
L
L
K
Y
R
Q
S
T
L
N
S
G
L
N
F
Site 13
S153
Y
R
Q
S
T
L
N
S
G
L
N
F
K
D
V
Site 14
Y181
T
N
V
I
V
L
S
Y
P
Q
Y
C
R
Y
R
Site 15
Y184
I
V
L
S
Y
P
Q
Y
C
R
Y
R
S
M
L
Site 16
Y187
S
Y
P
Q
Y
C
R
Y
R
S
M
L
K
R
I
Site 17
S199
K
R
I
Q
D
K
P
S
S
I
L
T
D
Q
F
Site 18
S200
R
I
Q
D
K
P
S
S
I
L
T
D
Q
F
A
Site 19
Y224
S
R
N
P
Q
I
L
Y
C
R
D
T
F
D
H
Site 20
T228
Q
I
L
Y
C
R
D
T
F
D
H
P
T
L
I
Site 21
T233
R
D
T
F
D
H
P
T
L
I
E
N
E
S
I
Site 22
S239
P
T
L
I
E
N
E
S
I
C
D
E
F
A
P
Site 23
S264
P
C
P
Q
R
R
D
S
F
S
G
V
K
D
S
Site 24
S266
P
Q
R
R
D
S
F
S
G
V
K
D
S
N
N
Site 25
S271
S
F
S
G
V
K
D
S
N
N
N
S
D
G
K
Site 26
S275
V
K
D
S
N
N
N
S
D
G
K
A
V
A
K
Site 27
S304
N
H
N
C
K
K
V
S
N
E
E
K
P
K
V
Site 28
Y329
Q
A
F
L
V
A
L
Y
K
Y
M
K
E
R
K
Site 29
T337
K
Y
M
K
E
R
K
T
P
I
E
R
I
P
Y
Site 30
Y344
T
P
I
E
R
I
P
Y
L
G
F
K
Q
I
N
Site 31
T369
L
G
G
Y
E
T
I
T
A
R
R
Q
W
K
H
Site 32
Y378
R
R
Q
W
K
H
I
Y
D
E
L
G
G
N
P
Site 33
S387
E
L
G
G
N
P
G
S
T
S
A
A
T
C
T
Site 34
S389
G
G
N
P
G
S
T
S
A
A
T
C
T
R
R
Site 35
T394
S
T
S
A
A
T
C
T
R
R
H
Y
E
R
L
Site 36
Y398
A
T
C
T
R
R
H
Y
E
R
L
I
L
P
Y
Site 37
Y405
Y
E
R
L
I
L
P
Y
E
R
F
I
K
G
E
Site 38
S428
K
P
R
K
Q
E
N
S
S
Q
E
N
E
N
K
Site 39
S429
P
R
K
Q
E
N
S
S
Q
E
N
E
N
K
T
Site 40
S451
I
K
H
E
I
P
K
S
K
K
E
K
E
N
A
Site 41
S480
K
E
Q
E
T
L
I
S
Q
K
S
I
P
E
P
Site 42
S483
E
T
L
I
S
Q
K
S
I
P
E
P
L
P
A
Site 43
Y500
M
K
K
K
I
E
G
Y
Q
E
F
S
A
K
P
Site 44
T520
D
P
E
K
D
N
E
T
D
Q
G
S
N
S
E
Site 45
S526
E
T
D
Q
G
S
N
S
E
K
V
A
E
E
A
Site 46
T539
E
A
G
E
K
G
P
T
P
P
L
P
S
A
P
Site 47
S544
G
P
T
P
P
L
P
S
A
P
L
A
P
E
K
Site 48
S553
P
L
A
P
E
K
D
S
A
L
V
P
G
A
S
Site 49
S560
S
A
L
V
P
G
A
S
K
Q
P
L
T
S
P
Site 50
T565
G
A
S
K
Q
P
L
T
S
P
S
A
L
V
D
Site 51
S566
A
S
K
Q
P
L
T
S
P
S
A
L
V
D
S
Site 52
S568
K
Q
P
L
T
S
P
S
A
L
V
D
S
K
Q
Site 53
S573
S
P
S
A
L
V
D
S
K
Q
E
S
K
L
C
Site 54
S577
L
V
D
S
K
Q
E
S
K
L
C
C
F
T
E
Site 55
T583
E
S
K
L
C
C
F
T
E
S
P
E
S
E
P
Site 56
S585
K
L
C
C
F
T
E
S
P
E
S
E
P
Q
E
Site 57
S588
C
F
T
E
S
P
E
S
E
P
Q
E
A
S
F
Site 58
S594
E
S
E
P
Q
E
A
S
F
P
S
F
P
T
T
Site 59
S597
P
Q
E
A
S
F
P
S
F
P
T
T
Q
P
P
Site 60
T601
S
F
P
S
F
P
T
T
Q
P
P
L
A
N
Q
Site 61
S635
V
K
V
D
Q
L
G
S
D
D
I
H
N
A
L
Site 62
S653
P
K
V
L
V
V
Q
S
F
D
M
F
K
D
K
Site 63
T663
M
F
K
D
K
D
L
T
G
P
M
N
E
N
H
Site 64
T675
E
N
H
G
L
N
Y
T
P
L
L
Y
S
R
G
Site 65
Y679
L
N
Y
T
P
L
L
Y
S
R
G
N
P
G
I
Site 66
S680
N
Y
T
P
L
L
Y
S
R
G
N
P
G
I
M
Site 67
S688
R
G
N
P
G
I
M
S
P
L
A
K
K
K
L
Site 68
S700
K
K
L
L
S
Q
V
S
G
A
S
L
S
S
S
Site 69
S703
L
S
Q
V
S
G
A
S
L
S
S
S
Y
P
Y
Site 70
S705
Q
V
S
G
A
S
L
S
S
S
Y
P
Y
G
S
Site 71
S706
V
S
G
A
S
L
S
S
S
Y
P
Y
G
S
P
Site 72
S707
S
G
A
S
L
S
S
S
Y
P
Y
G
S
P
P
Site 73
Y708
G
A
S
L
S
S
S
Y
P
Y
G
S
P
P
P
Site 74
Y710
S
L
S
S
S
Y
P
Y
G
S
P
P
P
L
I
Site 75
S712
S
S
S
Y
P
Y
G
S
P
P
P
L
I
S
K
Site 76
S718
G
S
P
P
P
L
I
S
K
K
K
L
I
A
R
Site 77
S730
I
A
R
D
D
L
C
S
S
L
S
Q
T
H
H
Site 78
S731
A
R
D
D
L
C
S
S
L
S
Q
T
H
H
G
Site 79
S733
D
D
L
C
S
S
L
S
Q
T
H
H
G
Q
S
Site 80
T735
L
C
S
S
L
S
Q
T
H
H
G
Q
S
T
D
Site 81
S747
S
T
D
H
M
A
V
S
R
P
S
V
I
Q
H
Site 82
S750
H
M
A
V
S
R
P
S
V
I
Q
H
V
Q
S
Site 83
S757
S
V
I
Q
H
V
Q
S
F
R
S
K
P
S
E
Site 84
T768
K
P
S
E
E
R
K
T
I
N
D
I
F
K
H
Site 85
S779
I
F
K
H
E
K
L
S
R
S
D
P
H
R
C
Site 86
S781
K
H
E
K
L
S
R
S
D
P
H
R
C
S
F
Site 87
S787
R
S
D
P
H
R
C
S
F
S
K
H
H
L
N
Site 88
S799
H
L
N
P
L
A
D
S
Y
V
L
K
Q
E
I
Site 89
Y800
L
N
P
L
A
D
S
Y
V
L
K
Q
E
I
Q
Site 90
S822
E
K
R
A
L
P
H
S
H
M
P
S
F
L
A
Site 91
S826
L
P
H
S
H
M
P
S
F
L
A
D
F
Y
S
Site 92
Y832
P
S
F
L
A
D
F
Y
S
S
P
H
L
H
S
Site 93
S833
S
F
L
A
D
F
Y
S
S
P
H
L
H
S
L
Site 94
S834
F
L
A
D
F
Y
S
S
P
H
L
H
S
L
Y
Site 95
S839
Y
S
S
P
H
L
H
S
L
Y
R
H
T
E
H
Site 96
Y841
S
P
H
L
H
S
L
Y
R
H
T
E
H
H
L
Site 97
Y856
H
N
E
Q
T
S
K
Y
P
S
R
D
M
Y
R
Site 98
S858
E
Q
T
S
K
Y
P
S
R
D
M
Y
R
E
S
Site 99
Y862
K
Y
P
S
R
D
M
Y
R
E
S
E
N
S
S
Site 100
S865
S
R
D
M
Y
R
E
S
E
N
S
S
F
P
S
Site 101
S868
M
Y
R
E
S
E
N
S
S
F
P
S
H
R
H
Site 102
S869
Y
R
E
S
E
N
S
S
F
P
S
H
R
H
Q
Site 103
S872
S
E
N
S
S
F
P
S
H
R
H
Q
E
K
L
Site 104
S894
L
H
L
Q
D
K
K
S
A
A
A
E
A
P
T
Site 105
T906
A
P
T
D
D
Q
P
T
D
L
S
L
P
K
N
Site 106
S909
D
D
Q
P
T
D
L
S
L
P
K
N
P
H
K
Site 107
S927
K
V
L
G
L
A
H
S
T
T
G
P
Q
E
S
Site 108
T929
L
G
L
A
H
S
T
T
G
P
Q
E
S
K
G
Site 109
S934
S
T
T
G
P
Q
E
S
K
G
I
S
Q
F
Q
Site 110
S938
P
Q
E
S
K
G
I
S
Q
F
Q
V
L
G
S
Site 111
S945
S
Q
F
Q
V
L
G
S
Q
S
R
D
C
H
P
Site 112
S947
F
Q
V
L
G
S
Q
S
R
D
C
H
P
K
A
Site 113
S958
H
P
K
A
C
R
V
S
P
M
T
M
S
G
P
Site 114
T961
A
C
R
V
S
P
M
T
M
S
G
P
K
K
Y
Site 115
S963
R
V
S
P
M
T
M
S
G
P
K
K
Y
P
E
Site 116
Y968
T
M
S
G
P
K
K
Y
P
E
S
L
S
R
S
Site 117
S971
G
P
K
K
Y
P
E
S
L
S
R
S
G
K
P
Site 118
S973
K
K
Y
P
E
S
L
S
R
S
G
K
P
H
H
Site 119
S975
Y
P
E
S
L
S
R
S
G
K
P
H
H
V
R
Site 120
S1002
P
I
L
H
R
K
M
S
P
Q
N
I
G
A
A
Site 121
S1015
A
A
R
P
I
K
R
S
L
E
D
L
D
L
V
Site 122
S1032
G
K
K
A
R
A
V
S
P
L
D
P
S
K
E
Site 123
S1037
A
V
S
P
L
D
P
S
K
E
V
S
G
K
E
Site 124
S1041
L
D
P
S
K
E
V
S
G
K
E
K
A
S
E
Site 125
S1047
V
S
G
K
E
K
A
S
E
Q
E
S
E
G
S
Site 126
S1051
E
K
A
S
E
Q
E
S
E
G
S
K
A
A
H
Site 127
S1054
S
E
Q
E
S
E
G
S
K
A
A
H
G
G
H
Site 128
S1062
K
A
A
H
G
G
H
S
G
G
G
S
E
G
H
Site 129
S1066
G
G
H
S
G
G
G
S
E
G
H
K
L
P
L
Site 130
S1074
E
G
H
K
L
P
L
S
S
P
I
F
P
G
L
Site 131
S1089
Y
S
G
S
L
C
N
S
G
L
N
S
R
L
P
Site 132
S1093
L
C
N
S
G
L
N
S
R
L
P
A
G
Y
S
Site 133
S1100
S
R
L
P
A
G
Y
S
H
S
L
Q
Y
L
K
Site 134
S1102
L
P
A
G
Y
S
H
S
L
Q
Y
L
K
N
Q
Site 135
S1133
M
Q
R
G
I
F
T
S
P
T
N
S
Q
Q
L
Site 136
T1135
R
G
I
F
T
S
P
T
N
S
Q
Q
L
Y
R
Site 137
S1137
I
F
T
S
P
T
N
S
Q
Q
L
Y
R
H
L
Site 138
Y1141
P
T
N
S
Q
Q
L
Y
R
H
L
A
A
A
T
Site 139
T1148
Y
R
H
L
A
A
A
T
P
V
G
S
S
Y
G
Site 140
S1176
N
P
Q
A
A
F
P
S
S
Q
L
S
S
V
H
Site 141
S1177
P
Q
A
A
F
P
S
S
Q
L
S
S
V
H
P
Site 142
S1180
A
F
P
S
S
Q
L
S
S
V
H
P
S
T
K
Site 143
S1181
F
P
S
S
Q
L
S
S
V
H
P
S
T
K
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation