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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NFI-X
Full Name:
Nuclear factor 1 X-type
Alias:
CCAAT-binding transcription factor; CCAAT-box binding transcription factor; CTF; NF1A; NF1-X; NF-I/X; NFIX; Nuclear factor 1 X-type: NFI-X: NF-I/X: CCAAT-box-binding transcription factor: TGGCA-binding protein: Nuclear factor 1 X-type: NFI-X: NF-I/X: CCAAT-box-binding transcription factor: TGGCA-binding protein: Nuclear factor 1 X-type: NFI-X: NF-I/X: CCAAT-box-binding transcription factor: TGGCA-binding protein: Nuclear factor 1 X-type: NFI-X: NF-I/X: CCAAT-box-binding transcription factor: TGGCA-binding protein; Nuclear factor 1/X; Nuclear factor I/X; Nuclear factor I/X (CCAAT-binding transcription factor); TGGCA-binding protein
Type:
Transcription protein
Mass (Da):
55098
Number AA:
502
UniProt ID:
Q14938
International Prot ID:
IPI00218260
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003705
PhosphoSite+
KinaseNET
Biological Process:
GO:0006260
GO:0006355
GO:0006366
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y40
L
Q
A
R
K
R
K
Y
F
K
K
H
E
K
R
Site 2
S49
K
K
H
E
K
R
M
S
K
D
E
E
R
A
V
Site 3
S106
K
P
P
C
C
V
L
S
N
P
D
Q
K
G
K
Site 4
S144
F
K
G
I
P
L
E
S
T
D
G
E
R
L
Y
Site 5
T145
K
G
I
P
L
E
S
T
D
G
E
R
L
Y
K
Site 6
Y151
S
T
D
G
E
R
L
Y
K
S
P
Q
C
S
N
Site 7
S153
D
G
E
R
L
Y
K
S
P
Q
C
S
N
P
G
Site 8
S157
L
Y
K
S
P
Q
C
S
N
P
G
L
C
V
Q
Site 9
Y181
E
L
D
L
Y
L
A
Y
F
V
H
T
P
E
S
Site 10
T185
Y
L
A
Y
F
V
H
T
P
E
S
G
Q
S
D
Site 11
S188
Y
F
V
H
T
P
E
S
G
Q
S
D
S
S
N
Site 12
S191
H
T
P
E
S
G
Q
S
D
S
S
N
Q
Q
G
Site 13
S193
P
E
S
G
Q
S
D
S
S
N
Q
Q
G
D
A
Site 14
S194
E
S
G
Q
S
D
S
S
N
Q
Q
G
D
A
D
Site 15
S211
P
L
P
N
G
H
L
S
F
Q
D
C
F
V
T
Site 16
S244
T
A
S
G
P
N
F
S
L
A
D
L
E
S
P
Site 17
S250
F
S
L
A
D
L
E
S
P
S
Y
Y
N
I
N
Site 18
Y253
A
D
L
E
S
P
S
Y
Y
N
I
N
Q
V
T
Site 19
Y254
D
L
E
S
P
S
Y
Y
N
I
N
Q
V
T
L
Site 20
S265
Q
V
T
L
G
R
R
S
I
T
S
P
P
S
T
Site 21
T267
T
L
G
R
R
S
I
T
S
P
P
S
T
S
T
Site 22
S268
L
G
R
R
S
I
T
S
P
P
S
T
S
T
T
Site 23
S271
R
S
I
T
S
P
P
S
T
S
T
T
K
R
P
Site 24
T272
S
I
T
S
P
P
S
T
S
T
T
K
R
P
K
Site 25
S273
I
T
S
P
P
S
T
S
T
T
K
R
P
K
S
Site 26
T275
S
P
P
S
T
S
T
T
K
R
P
K
S
I
D
Site 27
S280
S
T
T
K
R
P
K
S
I
D
D
S
E
M
E
Site 28
S284
R
P
K
S
I
D
D
S
E
M
E
S
P
V
D
Site 29
S288
I
D
D
S
E
M
E
S
P
V
D
D
V
F
Y
Site 30
Y295
S
P
V
D
D
V
F
Y
P
G
T
G
R
S
P
Site 31
T298
D
D
V
F
Y
P
G
T
G
R
S
P
A
A
G
Site 32
S301
F
Y
P
G
T
G
R
S
P
A
A
G
S
S
Q
Site 33
S306
G
R
S
P
A
A
G
S
S
Q
S
S
G
W
P
Site 34
S307
R
S
P
A
A
G
S
S
Q
S
S
G
W
P
N
Site 35
S310
A
A
G
S
S
Q
S
S
G
W
P
N
D
V
D
Site 36
S322
D
V
D
A
G
P
A
S
L
K
K
S
G
K
L
Site 37
S326
G
P
A
S
L
K
K
S
G
K
L
D
F
C
S
Site 38
S333
S
G
K
L
D
F
C
S
A
L
S
S
Q
G
S
Site 39
S336
L
D
F
C
S
A
L
S
S
Q
G
S
S
P
R
Site 40
S337
D
F
C
S
A
L
S
S
Q
G
S
S
P
R
M
Site 41
S340
S
A
L
S
S
Q
G
S
S
P
R
M
A
F
T
Site 42
S341
A
L
S
S
Q
G
S
S
P
R
M
A
F
T
H
Site 43
T347
S
S
P
R
M
A
F
T
H
H
P
L
P
V
L
Site 44
S361
L
A
G
V
R
P
G
S
P
R
A
T
A
S
A
Site 45
T365
R
P
G
S
P
R
A
T
A
S
A
L
H
F
P
Site 46
S367
G
S
P
R
A
T
A
S
A
L
H
F
P
S
T
Site 47
S373
A
S
A
L
H
F
P
S
T
S
I
I
Q
Q
S
Site 48
T374
S
A
L
H
F
P
S
T
S
I
I
Q
Q
S
S
Site 49
S375
A
L
H
F
P
S
T
S
I
I
Q
Q
S
S
P
Site 50
S380
S
T
S
I
I
Q
Q
S
S
P
Y
F
T
H
P
Site 51
S381
T
S
I
I
Q
Q
S
S
P
Y
F
T
H
P
T
Site 52
T385
Q
Q
S
S
P
Y
F
T
H
P
T
I
R
Y
H
Site 53
S412
Q
F
V
C
S
D
G
S
G
Q
A
T
G
Q
P
Site 54
T416
S
D
G
S
G
Q
A
T
G
Q
P
N
G
S
G
Site 55
S422
A
T
G
Q
P
N
G
S
G
Q
G
K
V
P
G
Site 56
S430
G
Q
G
K
V
P
G
S
F
L
L
P
P
P
P
Site 57
S450
V
P
L
P
M
P
D
S
K
S
T
S
T
A
P
Site 58
S452
L
P
M
P
D
S
K
S
T
S
T
A
P
D
G
Site 59
S454
M
P
D
S
K
S
T
S
T
A
P
D
G
A
A
Site 60
T463
A
P
D
G
A
A
L
T
P
P
S
P
S
F
A
Site 61
S468
A
L
T
P
P
S
P
S
F
A
T
T
G
A
S
Site 62
T471
P
P
S
P
S
F
A
T
T
G
A
S
S
A
N
Site 63
T472
P
S
P
S
F
A
T
T
G
A
S
S
A
N
R
Site 64
S482
S
S
A
N
R
F
V
S
I
G
P
R
D
G
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation