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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NR1I3
Full Name:
Nuclear receptor subfamily 1 group I member 3
Alias:
CAR; CAR1; Constitutive activator of retinoid response; Constitutive androstane receptor; MB67; Nuclear receptor subfamily 1, group I, member 3; Orphan nuclear receptor MB67; Orphan nuclear receptor NR1I3
Type:
Receptor, nuclear
Mass (Da):
39942
Number AA:
352
UniProt ID:
Q14994
International Prot ID:
IPI00418379
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0004882
GO:0043565
GO:0003713
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0007165
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T38
C
K
G
F
F
R
R
T
V
S
K
S
I
G
P
Site 2
S40
G
F
F
R
R
T
V
S
K
S
I
G
P
T
C
Site 3
S42
F
R
R
T
V
S
K
S
I
G
P
T
C
P
F
Site 4
S52
P
T
C
P
F
A
G
S
C
E
V
S
K
T
Q
Site 5
T58
G
S
C
E
V
S
K
T
Q
R
R
H
C
P
A
Site 6
T102
A
Q
R
R
A
Q
Q
T
P
V
Q
L
S
K
E
Site 7
T116
E
Q
E
E
L
I
R
T
L
L
G
A
H
T
R
Site 8
S184
K
D
L
P
V
F
R
S
L
P
I
E
D
Q
I
Site 9
S192
L
P
I
E
D
Q
I
S
L
L
K
G
A
A
V
Site 10
T225
L
C
G
P
L
R
Y
T
I
E
D
G
A
R
V
Site 11
T235
D
G
A
R
V
S
P
T
V
G
F
Q
V
E
F
Site 12
T280
S
P
D
R
P
G
V
T
Q
R
D
E
I
D
Q
Site 13
T295
L
Q
E
E
M
A
L
T
L
Q
S
Y
I
K
G
Site 14
Y313
R
P
R
D
R
F
L
Y
A
K
L
L
G
L
L
Site 15
S325
G
L
L
A
E
L
R
S
I
N
E
A
Y
G
Y
Site 16
Y332
S
I
N
E
A
Y
G
Y
Q
I
Q
H
I
Q
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation