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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NR1D2
Full Name:
Nuclear receptor subfamily 1 group D member 2
Alias:
Orphan nuclear hormone receptor BD73;Rev-erb-beta;V-erbA-related protein 1-related
Type:
Mass (Da):
64625
Number AA:
579
UniProt ID:
Q14995
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
I
A
Y
I
S
S
S
S
S
A
S
S
P
A
S
Site 2
S17
A
Y
I
S
S
S
S
S
A
S
S
P
A
S
C
Site 3
S19
I
S
S
S
S
S
A
S
S
P
A
S
C
H
S
Site 4
S20
S
S
S
S
S
A
S
S
P
A
S
C
H
S
E
Site 5
S23
S
S
A
S
S
P
A
S
C
H
S
E
G
S
E
Site 6
S26
S
S
P
A
S
C
H
S
E
G
S
E
N
S
F
Site 7
S29
A
S
C
H
S
E
G
S
E
N
S
F
Q
S
S
Site 8
S32
H
S
E
G
S
E
N
S
F
Q
S
S
S
S
S
Site 9
S35
G
S
E
N
S
F
Q
S
S
S
S
S
V
P
S
Site 10
S36
S
E
N
S
F
Q
S
S
S
S
S
V
P
S
S
Site 11
S37
E
N
S
F
Q
S
S
S
S
S
V
P
S
S
P
Site 12
S38
N
S
F
Q
S
S
S
S
S
V
P
S
S
P
N
Site 13
S39
S
F
Q
S
S
S
S
S
V
P
S
S
P
N
S
Site 14
S42
S
S
S
S
S
V
P
S
S
P
N
S
S
N
S
Site 15
S43
S
S
S
S
V
P
S
S
P
N
S
S
N
S
D
Site 16
S46
S
V
P
S
S
P
N
S
S
N
S
D
T
N
G
Site 17
S47
V
P
S
S
P
N
S
S
N
S
D
T
N
G
N
Site 18
S49
S
S
P
N
S
S
N
S
D
T
N
G
N
P
K
Site 19
T51
P
N
S
S
N
S
D
T
N
G
N
P
K
N
G
Site 20
S75
K
N
D
R
I
D
C
S
M
K
T
S
K
S
S
Site 21
T78
R
I
D
C
S
M
K
T
S
K
S
S
A
P
G
Site 22
S79
I
D
C
S
M
K
T
S
K
S
S
A
P
G
M
Site 23
S81
C
S
M
K
T
S
K
S
S
A
P
G
M
T
K
Site 24
T87
K
S
S
A
P
G
M
T
K
S
H
S
G
V
T
Site 25
S89
S
A
P
G
M
T
K
S
H
S
G
V
T
K
F
Site 26
S91
P
G
M
T
K
S
H
S
G
V
T
K
F
S
G
Site 27
Y115
D
V
A
S
G
F
H
Y
G
V
H
A
C
E
G
Site 28
S166
C
R
F
K
K
C
L
S
V
G
M
S
R
D
A
Site 29
T211
S
G
H
L
Q
N
D
T
L
V
E
H
H
E
Q
Site 30
S240
L
E
Q
E
N
I
K
S
S
S
P
P
S
S
D
Site 31
S241
E
Q
E
N
I
K
S
S
S
P
P
S
S
D
F
Site 32
S242
Q
E
N
I
K
S
S
S
P
P
S
S
D
F
A
Site 33
S245
I
K
S
S
S
P
P
S
S
D
F
A
K
E
E
Site 34
S246
K
S
S
S
P
P
S
S
D
F
A
K
E
E
V
Site 35
S307
H
C
G
N
G
L
S
S
H
F
P
C
S
E
S
Site 36
S312
L
S
S
H
F
P
C
S
E
S
Q
Q
H
L
N
Site 37
S314
S
H
F
P
C
S
E
S
Q
Q
H
L
N
G
Q
Site 38
S364
R
V
P
I
D
G
F
S
Q
N
E
N
K
N
S
Site 39
S371
S
Q
N
E
N
K
N
S
Y
L
C
N
T
G
G
Site 40
Y372
Q
N
E
N
K
N
S
Y
L
C
N
T
G
G
R
Site 41
S387
M
H
L
V
C
P
L
S
K
S
P
Y
V
D
P
Site 42
S389
L
V
C
P
L
S
K
S
P
Y
V
D
P
H
K
Site 43
Y391
C
P
L
S
K
S
P
Y
V
D
P
H
K
S
G
Site 44
S408
I
W
E
E
F
S
M
S
F
T
P
A
V
K
E
Site 45
S430
I
P
G
F
R
D
L
S
Q
H
D
Q
V
N
L
Site 46
T460
L
F
D
A
K
E
R
T
V
T
F
L
S
G
K
Site 47
T462
D
A
K
E
R
T
V
T
F
L
S
G
K
K
Y
Site 48
S465
E
R
T
V
T
F
L
S
G
K
K
Y
S
V
D
Site 49
Y469
T
F
L
S
G
K
K
Y
S
V
D
D
L
H
S
Site 50
S470
F
L
S
G
K
K
Y
S
V
D
D
L
H
S
M
Site 51
S476
Y
S
V
D
D
L
H
S
M
G
A
G
D
L
L
Site 52
S485
G
A
G
D
L
L
N
S
M
F
E
F
S
E
K
Site 53
S499
K
L
N
A
L
Q
L
S
D
E
E
M
S
L
F
Site 54
S517
V
L
V
S
A
D
R
S
G
I
E
N
V
N
S
Site 55
S524
S
G
I
E
N
V
N
S
V
E
A
L
Q
E
T
Site 56
S549
K
N
H
P
N
E
A
S
I
F
T
K
L
L
L
Site 57
S563
L
K
L
P
D
L
R
S
L
N
N
M
H
S
E
Site 58
S569
R
S
L
N
N
M
H
S
E
E
L
L
A
F
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation