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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ARHGAP19
Full Name:
Rho GTPase-activating protein 19
Alias:
FLJ00194; MGC14258; RHG19; Rho GTPase activating 19; Rho GTPase activating protein 19; Rho-type GTPase-activating 19
Type:
GTPase activating protein, Rac/Rho
Mass (Da):
55760
Number AA:
UniProt ID:
Q14CB8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005096
PhosphoSite+
KinaseNET
Biological Process:
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S16
G
E
V
P
A
R
E
S
G
R
S
D
A
I
C
Site 2
S19
P
A
R
E
S
G
R
S
D
A
I
C
S
F
V
Site 3
S31
S
F
V
I
C
N
D
S
S
L
R
G
Q
P
I
Site 4
S100
P
A
S
G
F
F
R
S
L
M
S
L
K
R
K
Site 5
S103
G
F
F
R
S
L
M
S
L
K
R
K
E
K
G
Site 6
S115
E
K
G
V
I
F
G
S
P
L
T
E
E
G
I
Site 7
Y126
E
E
G
I
A
Q
I
Y
Q
L
I
E
Y
L
H
Site 8
Y131
Q
I
Y
Q
L
I
E
Y
L
H
K
N
L
R
V
Site 9
S148
L
F
R
V
P
G
N
S
V
R
Q
Q
I
L
R
Site 10
S168
G
T
D
I
D
L
E
S
G
E
F
H
S
N
D
Site 11
S173
L
E
S
G
E
F
H
S
N
D
V
A
T
L
L
Site 12
T193
E
L
P
E
P
L
L
T
H
K
H
F
N
A
H
Site 13
T216
F
D
D
K
G
N
K
T
N
I
P
D
K
D
R
Site 14
Y251
K
L
L
L
D
L
L
Y
Q
T
A
K
K
Q
D
Site 15
Y313
K
L
F
K
A
P
A
Y
I
R
E
C
A
R
L
Site 16
Y322
R
E
C
A
R
L
H
Y
L
G
S
R
T
Q
A
Site 17
S325
A
R
L
H
Y
L
G
S
R
T
Q
A
S
K
D
Site 18
S330
L
G
S
R
T
Q
A
S
K
D
D
L
D
L
I
Site 19
S339
D
D
L
D
L
I
A
S
C
H
T
K
S
F
Q
Site 20
S344
I
A
S
C
H
T
K
S
F
Q
L
A
K
S
Q
Site 21
S350
K
S
F
Q
L
A
K
S
Q
K
R
N
R
V
D
Site 22
S358
Q
K
R
N
R
V
D
S
C
P
H
Q
E
E
T
Site 23
S386
H
V
H
D
M
P
E
S
A
K
K
K
Q
L
I
Site 24
S400
I
R
Q
F
N
K
Q
S
L
T
Q
T
P
G
R
Site 25
T402
Q
F
N
K
Q
S
L
T
Q
T
P
G
R
E
P
Site 26
T404
N
K
Q
S
L
T
Q
T
P
G
R
E
P
S
T
Site 27
S410
Q
T
P
G
R
E
P
S
T
S
Q
V
Q
K
R
Site 28
S412
P
G
R
E
P
S
T
S
Q
V
Q
K
R
A
R
Site 29
S420
Q
V
Q
K
R
A
R
S
R
S
F
S
G
L
I
Site 30
S422
Q
K
R
A
R
S
R
S
F
S
G
L
I
K
R
Site 31
S424
R
A
R
S
R
S
F
S
G
L
I
K
R
K
V
Site 32
T446
E
K
K
K
K
N
P
T
P
E
S
V
A
I
G
Site 33
S449
K
K
N
P
T
P
E
S
V
A
I
G
E
L
K
Site 34
S468
E
N
R
N
L
L
F
S
G
S
P
A
V
T
M
Site 35
S470
R
N
L
L
F
S
G
S
P
A
V
T
M
T
P
Site 36
T474
F
S
G
S
P
A
V
T
M
T
P
T
R
L
K
Site 37
T476
G
S
P
A
V
T
M
T
P
T
R
L
K
W
S
Site 38
T478
P
A
V
T
M
T
P
T
R
L
K
W
S
E
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation