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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FASTKD3
Full Name:
FAST kinase domain-containing protein 3
Alias:
fakd3; fast kinase domains 3; fastkd3; flj23274; mgc142123; mgc5297
Type:
Mass (Da):
75720
Number AA:
UniProt ID:
Q14CZ7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0004672
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
R
K
N
L
Y
R
L
S
D
F
Q
M
H
R
A
Site 2
S82
P
L
G
G
P
V
F
S
Q
V
S
D
C
D
R
Site 3
S85
G
P
V
F
S
Q
V
S
D
C
D
R
L
E
Q
Site 4
Y103
N
E
E
S
Q
M
F
Y
R
R
L
S
N
L
T
Site 5
S107
Q
M
F
Y
R
R
L
S
N
L
T
S
S
E
E
Site 6
T110
Y
R
R
L
S
N
L
T
S
S
E
E
V
L
S
Site 7
S111
R
R
L
S
N
L
T
S
S
E
E
V
L
S
F
Site 8
S117
T
S
S
E
E
V
L
S
F
I
S
T
M
E
T
Site 9
S171
F
Q
F
E
K
E
P
S
Q
L
S
N
T
S
L
Site 10
S174
E
K
E
P
S
Q
L
S
N
T
S
L
V
T
A
Site 11
T250
L
Q
G
E
K
L
E
T
F
T
P
E
D
I
V
Site 12
T252
G
E
K
L
E
T
F
T
P
E
D
I
V
A
L
Site 13
S309
A
L
V
V
L
D
Q
S
Q
A
F
P
L
I
I
Site 14
T330
V
R
H
V
P
H
F
T
N
E
E
L
R
R
V
Site 15
T400
A
E
T
F
V
C
Q
T
E
K
F
S
P
R
Q
Site 16
S404
V
C
Q
T
E
K
F
S
P
R
Q
I
S
A
L
Site 17
S409
K
F
S
P
R
Q
I
S
A
L
M
E
P
F
G
Site 18
Y420
E
P
F
G
K
L
N
Y
L
P
P
N
A
S
A
Site 19
S447
F
N
Y
F
P
P
K
S
L
L
K
L
L
H
S
Site 20
S483
Q
R
L
Q
G
K
E
S
H
L
D
T
L
S
R
Site 21
T487
G
K
E
S
H
L
D
T
L
S
R
A
Q
L
T
Site 22
S489
E
S
H
L
D
T
L
S
R
A
Q
L
T
Q
L
Site 23
Y516
G
P
K
L
L
P
K
Y
Q
V
K
S
F
L
T
Site 24
S520
L
P
K
Y
Q
V
K
S
F
L
T
P
C
C
S
Site 25
T530
T
P
C
C
S
L
E
T
P
V
D
S
Q
L
Y
Site 26
S534
S
L
E
T
P
V
D
S
Q
L
Y
R
Y
V
K
Site 27
Y537
T
P
V
D
S
Q
L
Y
R
Y
V
K
I
G
L
Site 28
Y539
V
D
S
Q
L
Y
R
Y
V
K
I
G
L
T
N
Site 29
Y553
N
L
L
G
A
R
L
Y
F
A
P
K
V
L
T
Site 30
T582
E
G
F
V
L
P
S
T
A
N
E
D
I
H
K
Site 31
S603
D
G
P
K
R
F
C
S
N
S
K
H
L
L
G
Site 32
S605
P
K
R
F
C
S
N
S
K
H
L
L
G
K
E
Site 33
Y624
R
H
L
Q
L
L
G
Y
Q
V
V
Q
I
P
Y
Site 34
S639
H
E
I
G
M
L
K
S
R
R
E
L
V
E
Y
Site 35
Y646
S
R
R
E
L
V
E
Y
L
Q
R
K
L
F
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation