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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
VEPH1
Full Name:
Ventricular zone-expressed PH domain-containing protein homolog 1
Alias:
FLJ12604; KIAA1692; MELT; MGC111426; MGC126709; MGC142115; ventricular zone expressed PH domain homolog 1 (zebrafish)
Type:
Uncharacterized
Mass (Da):
94745
Number AA:
833
UniProt ID:
Q14D04
International Prot ID:
IPI00447507
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005886
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
V
L
G
Q
K
D
L
S
R
A
G
D
L
F
S
Site 2
S22
S
R
A
G
D
L
F
S
L
D
D
S
E
I
E
Site 3
S26
D
L
F
S
L
D
D
S
E
I
E
D
S
L
T
Site 4
S31
D
D
S
E
I
E
D
S
L
T
E
A
L
E
Q
Site 5
T33
S
E
I
E
D
S
L
T
E
A
L
E
Q
I
K
Site 6
S43
L
E
Q
I
K
I
I
S
S
S
S
D
Y
Q
T
Site 7
S44
E
Q
I
K
I
I
S
S
S
S
D
Y
Q
T
N
Site 8
S45
Q
I
K
I
I
S
S
S
S
D
Y
Q
T
N
N
Site 9
S46
I
K
I
I
S
S
S
S
D
Y
Q
T
N
N
N
Site 10
Y48
I
I
S
S
S
S
D
Y
Q
T
N
N
N
D
Q
Site 11
T50
S
S
S
S
D
Y
Q
T
N
N
N
D
Q
A
V
Site 12
T66
E
I
C
I
T
R
I
T
T
A
I
R
E
T
E
Site 13
T72
I
T
T
A
I
R
E
T
E
S
I
E
K
H
A
Site 14
T103
P
F
G
K
D
E
D
T
P
H
A
K
I
A
S
Site 15
Y120
M
S
C
I
L
Q
N
Y
N
R
P
P
V
M
A
Site 16
S149
K
E
L
C
R
N
M
S
N
Y
L
S
L
A
A
Site 17
S153
R
N
M
S
N
Y
L
S
L
A
A
I
T
K
A
Site 18
S208
T
E
L
L
A
L
M
S
Q
L
E
Q
P
E
Q
Site 19
Y216
Q
L
E
Q
P
E
Q
Y
H
L
L
R
L
L
H
Site 20
T249
I
G
H
L
K
D
S
T
H
N
D
I
I
L
N
Site 21
Y285
E
I
G
E
R
F
P
Y
L
T
G
Q
M
A
R
Site 22
T287
G
E
R
F
P
Y
L
T
G
Q
M
A
R
I
Y
Site 23
Y294
T
G
Q
M
A
R
I
Y
G
A
V
G
H
V
D
Site 24
S307
V
D
E
E
R
A
R
S
C
L
T
Y
L
V
S
Site 25
T310
E
R
A
R
S
C
L
T
Y
L
V
S
Q
L
A
Site 26
Y311
R
A
R
S
C
L
T
Y
L
V
S
Q
L
A
N
Site 27
S339
K
S
I
T
D
T
F
S
S
I
L
G
P
Q
S
Site 28
S340
S
I
T
D
T
F
S
S
I
L
G
P
Q
S
R
Site 29
S346
S
S
I
L
G
P
Q
S
R
D
I
F
R
M
S
Site 30
S353
S
R
D
I
F
R
M
S
N
S
F
T
A
I
A
Site 31
T370
L
T
R
Q
L
E
N
T
K
A
G
S
G
R
R
Site 32
S374
L
E
N
T
K
A
G
S
G
R
R
K
I
S
T
Site 33
S380
G
S
G
R
R
K
I
S
T
E
I
E
F
P
E
Site 34
T381
S
G
R
R
K
I
S
T
E
I
E
F
P
E
K
Site 35
T397
E
E
T
K
L
I
V
T
E
N
E
D
H
E
K
Site 36
S420
E
D
K
I
N
A
G
S
N
T
P
G
S
I
R
Site 37
T422
K
I
N
A
G
S
N
T
P
G
S
I
R
R
Y
Site 38
S425
A
G
S
N
T
P
G
S
I
R
R
Y
S
L
G
Site 39
Y429
T
P
G
S
I
R
R
Y
S
L
G
Q
V
S
K
Site 40
S430
P
G
S
I
R
R
Y
S
L
G
Q
V
S
K
E
Site 41
S449
I
R
F
N
R
S
K
S
L
A
F
H
T
M
L
Site 42
T457
L
A
F
H
T
M
L
T
K
G
V
G
S
D
D
Site 43
S476
N
R
G
D
I
P
A
S
I
S
L
S
E
I
D
Site 44
T496
N
D
K
L
P
F
K
T
D
T
E
R
S
Q
L
Site 45
T498
K
L
P
F
K
T
D
T
E
R
S
Q
L
G
E
Site 46
S501
F
K
T
D
T
E
R
S
Q
L
G
E
S
S
V
Site 47
S507
R
S
Q
L
G
E
S
S
V
S
Y
P
N
I
I
Site 48
S509
Q
L
G
E
S
S
V
S
Y
P
N
I
I
H
I
Site 49
Y510
L
G
E
S
S
V
S
Y
P
N
I
I
H
I
D
Site 50
S518
P
N
I
I
H
I
D
S
E
N
L
S
E
T
V
Site 51
S522
H
I
D
S
E
N
L
S
E
T
V
K
E
N
S
Site 52
T524
D
S
E
N
L
S
E
T
V
K
E
N
S
Q
E
Site 53
S529
S
E
T
V
K
E
N
S
Q
E
E
T
P
E
T
Site 54
T533
K
E
N
S
Q
E
E
T
P
E
T
T
A
S
P
Site 55
T536
S
Q
E
E
T
P
E
T
T
A
S
P
I
E
Y
Site 56
S539
E
T
P
E
T
T
A
S
P
I
E
Y
Q
D
K
Site 57
Y543
T
T
A
S
P
I
E
Y
Q
D
K
L
Y
L
H
Site 58
Y548
I
E
Y
Q
D
K
L
Y
L
H
L
K
K
N
L
Site 59
S556
L
H
L
K
K
N
L
S
K
V
K
A
Y
A
M
Site 60
T580
D
Q
C
T
I
E
D
T
V
R
S
C
V
A
K
Site 61
Y598
T
C
S
L
K
G
H
Y
C
L
Y
S
K
S
S
Site 62
S610
K
S
S
F
I
L
I
S
Q
E
P
Q
P
W
I
Site 63
S633
S
L
F
P
E
P
L
S
I
Q
S
H
S
V
Q
Site 64
S636
P
E
P
L
S
I
Q
S
H
S
V
Q
F
L
R
Site 65
T649
L
R
A
L
W
E
K
T
Q
A
G
G
A
H
S
Site 66
S656
T
Q
A
G
G
A
H
S
F
E
T
A
M
M
E
Site 67
T665
E
T
A
M
M
E
S
T
F
P
Q
Q
K
D
L
Site 68
T738
K
F
I
K
R
W
K
T
R
Y
F
T
L
A
G
Site 69
Y740
I
K
R
W
K
T
R
Y
F
T
L
A
G
N
Q
Site 70
T742
R
W
K
T
R
Y
F
T
L
A
G
N
Q
L
L
Site 71
S767
D
D
C
P
I
E
L
S
K
V
Q
S
V
K
A
Site 72
S771
I
E
L
S
K
V
Q
S
V
K
A
V
A
K
K
Site 73
S783
A
K
K
R
R
D
R
S
L
P
R
A
F
E
I
Site 74
T796
E
I
F
T
D
N
K
T
Y
V
F
K
A
K
D
Site 75
Y797
I
F
T
D
N
K
T
Y
V
F
K
A
K
D
E
Site 76
S826
A
Q
A
K
E
R
E
S
R
E
V
T
T
Y
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation