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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
WTAP
Full Name:
Pre-mRNA-splicing regulator WTAP
Alias:
Wilms tumor 1-associating protein
Type:
Uncharacterized protein
Mass (Da):
44244
Number AA:
396
UniProt ID:
Q15007
International Prot ID:
IPI00220302
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0031965
GO:0005730
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0008380
GO:0007049
GO:0006397
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T2
_
_
_
_
_
_
M
T
N
E
E
P
L
P
K
Site 2
S14
L
P
K
K
V
R
L
S
E
T
D
F
K
V
M
Site 3
Y36
R
W
K
Q
Y
E
A
Y
V
Q
A
L
E
G
K
Site 4
T45
Q
A
L
E
G
K
Y
T
D
L
N
S
N
D
V
Site 5
S49
G
K
Y
T
D
L
N
S
N
D
V
T
G
L
R
Site 6
T53
D
L
N
S
N
D
V
T
G
L
R
E
S
E
E
Site 7
S58
D
V
T
G
L
R
E
S
E
E
K
L
K
Q
Q
Site 8
S69
L
K
Q
Q
Q
Q
E
S
A
R
R
E
N
I
L
Site 9
T82
I
L
V
M
R
L
A
T
K
E
Q
E
M
Q
E
Site 10
S104
L
K
Q
V
Q
Q
P
S
V
A
Q
L
R
S
T
Site 11
T131
M
K
G
E
L
E
Q
T
K
D
K
L
E
Q
A
Site 12
S143
E
Q
A
Q
N
E
L
S
A
W
K
F
T
P
D
Site 13
T148
E
L
S
A
W
K
F
T
P
D
S
Q
T
G
K
Site 14
S151
A
W
K
F
T
P
D
S
Q
T
G
K
K
L
M
Site 15
S176
Q
E
L
G
R
Q
L
S
Q
G
R
I
A
Q
L
Site 16
S194
L
A
L
Q
K
K
Y
S
E
E
L
K
S
S
Q
Site 17
S199
K
Y
S
E
E
L
K
S
S
Q
D
E
L
N
D
Site 18
S200
Y
S
E
E
L
K
S
S
Q
D
E
L
N
D
F
Site 19
S220
E
E
V
E
G
M
Q
S
T
I
L
V
L
Q
Q
Site 20
S244
A
Q
Y
Q
Q
Q
Q
S
Q
A
S
A
P
S
T
Site 21
S247
Q
Q
Q
Q
S
Q
A
S
A
P
S
T
S
R
T
Site 22
S250
Q
S
Q
A
S
A
P
S
T
S
R
T
T
A
S
Site 23
T251
S
Q
A
S
A
P
S
T
S
R
T
T
A
S
E
Site 24
T254
S
A
P
S
T
S
R
T
T
A
S
E
P
V
E
Site 25
T255
A
P
S
T
S
R
T
T
A
S
E
P
V
E
Q
Site 26
S257
S
T
S
R
T
T
A
S
E
P
V
E
Q
S
E
Site 27
S263
A
S
E
P
V
E
Q
S
E
A
T
S
K
D
C
Site 28
S267
V
E
Q
S
E
A
T
S
K
D
C
S
R
L
T
Site 29
S271
E
A
T
S
K
D
C
S
R
L
T
N
G
P
S
Site 30
T274
S
K
D
C
S
R
L
T
N
G
P
S
N
G
S
Site 31
S278
S
R
L
T
N
G
P
S
N
G
S
S
S
R
Q
Site 32
S282
N
G
P
S
N
G
S
S
S
R
Q
R
T
S
G
Site 33
S283
G
P
S
N
G
S
S
S
R
Q
R
T
S
G
S
Site 34
T287
G
S
S
S
R
Q
R
T
S
G
S
G
F
H
R
Site 35
S288
S
S
S
R
Q
R
T
S
G
S
G
F
H
R
E
Site 36
S290
S
R
Q
R
T
S
G
S
G
F
H
R
E
G
N
Site 37
T298
G
F
H
R
E
G
N
T
T
E
D
D
F
P
S
Site 38
T299
F
H
R
E
G
N
T
T
E
D
D
F
P
S
S
Site 39
S305
T
T
E
D
D
F
P
S
S
P
G
N
G
N
K
Site 40
S306
T
E
D
D
F
P
S
S
P
G
N
G
N
K
S
Site 41
S313
S
P
G
N
G
N
K
S
S
N
S
S
E
E
R
Site 42
S314
P
G
N
G
N
K
S
S
N
S
S
E
E
R
T
Site 43
S316
N
G
N
K
S
S
N
S
S
E
E
R
T
G
R
Site 44
S317
G
N
K
S
S
N
S
S
E
E
R
T
G
R
G
Site 45
T321
S
N
S
S
E
E
R
T
G
R
G
G
S
G
Y
Site 46
S326
E
R
T
G
R
G
G
S
G
Y
V
N
Q
L
S
Site 47
Y328
T
G
R
G
G
S
G
Y
V
N
Q
L
S
A
G
Site 48
S333
S
G
Y
V
N
Q
L
S
A
G
Y
E
S
V
D
Site 49
Y336
V
N
Q
L
S
A
G
Y
E
S
V
D
S
P
T
Site 50
S338
Q
L
S
A
G
Y
E
S
V
D
S
P
T
G
S
Site 51
S341
A
G
Y
E
S
V
D
S
P
T
G
S
E
N
S
Site 52
S345
S
V
D
S
P
T
G
S
E
N
S
L
T
H
Q
Site 53
S348
S
P
T
G
S
E
N
S
L
T
H
Q
S
N
D
Site 54
T350
T
G
S
E
N
S
L
T
H
Q
S
N
D
T
D
Site 55
T356
L
T
H
Q
S
N
D
T
D
S
S
H
D
P
Q
Site 56
S358
H
Q
S
N
D
T
D
S
S
H
D
P
Q
E
E
Site 57
S359
Q
S
N
D
T
D
S
S
H
D
P
Q
E
E
K
Site 58
T375
V
S
G
K
G
N
R
T
V
G
S
R
H
V
Q
Site 59
S378
K
G
N
R
T
V
G
S
R
H
V
Q
N
G
L
Site 60
S387
H
V
Q
N
G
L
D
S
S
V
N
V
Q
G
S
Site 61
S388
V
Q
N
G
L
D
S
S
V
N
V
Q
G
S
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation