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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
FAM175B
Full Name:
BRISC complex subunit Abro1
Alias:
Abraxas brother; ABRO1; Em:AC068896.4; Family with sequence similarity 175, member B; K0157; KIAA0157
Type:
Unknown function
Mass (Da):
46901
Number AA:
415
UniProt ID:
Q15018
International Prot ID:
IPI00299517
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T37
G
E
V
R
Q
E
E
T
F
S
I
S
D
S
Q
Site 2
S39
V
R
Q
E
E
T
F
S
I
S
D
S
Q
I
S
Site 3
S41
Q
E
E
T
F
S
I
S
D
S
Q
I
S
N
T
Site 4
S43
E
T
F
S
I
S
D
S
Q
I
S
N
T
E
F
Site 5
S46
S
I
S
D
S
Q
I
S
N
T
E
F
L
Q
V
Site 6
S67
Q
P
C
S
K
L
F
S
F
Y
D
Y
A
S
K
Site 7
Y69
C
S
K
L
F
S
F
Y
D
Y
A
S
K
V
N
Site 8
Y71
K
L
F
S
F
Y
D
Y
A
S
K
V
N
E
E
Site 9
S73
F
S
F
Y
D
Y
A
S
K
V
N
E
E
S
L
Site 10
S79
A
S
K
V
N
E
E
S
L
D
R
I
L
K
D
Site 11
Y95
R
K
K
V
I
G
W
Y
R
F
R
R
N
T
Q
Site 12
T101
W
Y
R
F
R
R
N
T
Q
Q
Q
M
S
Y
R
Site 13
S106
R
N
T
Q
Q
Q
M
S
Y
R
E
Q
V
L
H
Site 14
Y107
N
T
Q
Q
Q
M
S
Y
R
E
Q
V
L
H
K
Site 15
Y145
N
S
T
H
A
L
E
Y
V
L
F
R
P
N
R
Site 16
Y154
L
F
R
P
N
R
R
Y
N
Q
R
I
S
L
A
Site 17
S159
R
R
Y
N
Q
R
I
S
L
A
I
P
N
L
G
Site 18
T168
A
I
P
N
L
G
N
T
S
Q
Q
E
Y
K
V
Site 19
S169
I
P
N
L
G
N
T
S
Q
Q
E
Y
K
V
S
Site 20
Y173
G
N
T
S
Q
Q
E
Y
K
V
S
S
V
P
N
Site 21
S176
S
Q
Q
E
Y
K
V
S
S
V
P
N
T
S
Q
Site 22
S177
Q
Q
E
Y
K
V
S
S
V
P
N
T
S
Q
S
Site 23
T181
K
V
S
S
V
P
N
T
S
Q
S
Y
A
K
V
Site 24
S182
V
S
S
V
P
N
T
S
Q
S
Y
A
K
V
I
Site 25
S184
S
V
P
N
T
S
Q
S
Y
A
K
V
I
K
E
Site 26
Y210
M
K
D
I
R
A
I
Y
Q
V
Y
N
A
L
Q
Site 27
Y213
I
R
A
I
Y
Q
V
Y
N
A
L
Q
E
K
V
Site 28
S230
V
C
A
D
V
E
K
S
E
R
V
V
E
S
C
Site 29
T249
N
K
L
R
R
Q
I
T
Q
R
K
N
E
K
E
Site 30
S267
R
L
Q
Q
A
V
L
S
R
Q
M
P
S
E
S
Site 31
S274
S
R
Q
M
P
S
E
S
L
D
P
A
F
S
P
Site 32
S280
E
S
L
D
P
A
F
S
P
R
M
P
S
S
G
Site 33
S285
A
F
S
P
R
M
P
S
S
G
F
A
A
E
G
Site 34
S286
F
S
P
R
M
P
S
S
G
F
A
A
E
G
R
Site 35
T295
F
A
A
E
G
R
S
T
L
G
D
A
E
A
S
Site 36
S302
T
L
G
D
A
E
A
S
D
P
P
P
P
Y
S
Site 37
Y308
A
S
D
P
P
P
P
Y
S
D
F
H
P
N
N
Site 38
S309
S
D
P
P
P
P
Y
S
D
F
H
P
N
N
Q
Site 39
S318
F
H
P
N
N
Q
E
S
T
L
S
H
S
R
M
Site 40
T319
H
P
N
N
Q
E
S
T
L
S
H
S
R
M
E
Site 41
S321
N
N
Q
E
S
T
L
S
H
S
R
M
E
R
S
Site 42
S328
S
H
S
R
M
E
R
S
V
F
M
P
R
P
Q
Site 43
S339
P
R
P
Q
A
V
G
S
S
N
Y
A
S
T
S
Site 44
S340
R
P
Q
A
V
G
S
S
N
Y
A
S
T
S
A
Site 45
Y342
Q
A
V
G
S
S
N
Y
A
S
T
S
A
G
L
Site 46
S344
V
G
S
S
N
Y
A
S
T
S
A
G
L
K
Y
Site 47
S346
S
S
N
Y
A
S
T
S
A
G
L
K
Y
P
G
Site 48
Y351
S
T
S
A
G
L
K
Y
P
G
S
G
A
D
L
Site 49
S354
A
G
L
K
Y
P
G
S
G
A
D
L
P
P
P
Site 50
S368
P
Q
R
A
A
G
D
S
G
E
D
S
D
D
S
Site 51
S372
A
G
D
S
G
E
D
S
D
D
S
D
Y
E
N
Site 52
S375
S
G
E
D
S
D
D
S
D
Y
E
N
L
I
D
Site 53
Y377
E
D
S
D
D
S
D
Y
E
N
L
I
D
P
T
Site 54
T384
Y
E
N
L
I
D
P
T
E
P
S
N
S
E
Y
Site 55
S387
L
I
D
P
T
E
P
S
N
S
E
Y
S
H
S
Site 56
S389
D
P
T
E
P
S
N
S
E
Y
S
H
S
K
D
Site 57
Y391
T
E
P
S
N
S
E
Y
S
H
S
K
D
S
R
Site 58
S392
E
P
S
N
S
E
Y
S
H
S
K
D
S
R
P
Site 59
S394
S
N
S
E
Y
S
H
S
K
D
S
R
P
M
A
Site 60
S397
E
Y
S
H
S
K
D
S
R
P
M
A
H
P
D
Site 61
T410
P
D
E
D
P
R
N
T
Q
T
S
Q
I
_
_
Site 62
S413
D
P
R
N
T
Q
T
S
Q
I
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation