PhosphoNET

           
Protein Info 
   
Short Name:  EXOSC7
Full Name:  Exosome complex exonuclease RRP42
Alias:  Ribosomal RNA-processing protein 42
Type: 
Mass (Da):  31817
Number AA:  291
UniProt ID:  Q15024
International Prot ID:  IPI00014198
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0000178  GO:0005634  GO:0032991 Uniprot OncoNet
Molecular Function:  GO:0000175  GO:0003676  GO:0003723 PhosphoSite+ KinaseNET
Biological Process:  GO:0006139  GO:0006364  GO:0006396 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T5___MASVTLSEAEKV
Site 2Y32DGRGCEDYRCVEVET
Site 3S43EVETDVVSNTSGSAR
Site 4S48VVSNTSGSARVKLGH
Site 5T68GVKAEMGTPKLEKPN
Site 6Y78LEKPNEGYLEFFVDC
Site 7T90VDCSASATPEFEGRG
Site 8T103RGGDDLGTEIANTLY
Site 9T108LGTEIANTLYRIFNN
Site 10Y110TEIANTLYRIFNNKS
Site 11S117YRIFNNKSSVDLKTL
Site 12S118RIFNNKSSVDLKTLC
Site 13T123KSSVDLKTLCISPRE
Site 14S183GSKDIELSDDPYDCI
Site 15Y187IELSDDPYDCIRLSV
Site 16T215YRHVVDATLQEEACS
Site 17S246MRKVGKGSLDPESIF
Site 18S251KGSLDPESIFEMMET
Site 19T258SIFEMMETGKRVGKV
Site 20S279SVLHKEESLGPKRQK
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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