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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CENTB1
Full Name:
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1
Alias:
ACAP1; ArfGAP with coiled-coil, ankyrin repeat and PH domains 1; CEB1; CENB1; Cnt-b1; KIAA0050; Similar to centaurin, beta 1
Type:
GTPase-activating protein for G protein, ARF
Mass (Da):
81536
Number AA:
740
UniProt ID:
Q15027
International Prot ID:
IPI00014199
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0008060
GO:0004629
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007242
GO:0006629
GO:0015031
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
F
E
E
C
L
K
D
S
P
R
F
R
A
S
I
Site 2
S20
D
S
P
R
F
R
A
S
I
E
L
V
E
A
E
Site 3
S29
E
L
V
E
A
E
V
S
E
L
E
T
R
L
E
Site 4
T43
E
K
L
L
K
L
G
T
G
L
L
E
S
G
R
Site 5
Y52
L
L
E
S
G
R
H
Y
L
A
A
S
R
A
F
Site 6
S86
C
L
E
K
F
T
V
S
L
N
H
K
L
D
S
Site 7
S93
S
L
N
H
K
L
D
S
H
A
E
L
L
D
A
Site 8
S133
D
F
W
R
G
A
E
S
L
E
A
A
L
T
H
Site 9
T139
E
S
L
E
A
A
L
T
H
N
A
E
V
P
R
Site 10
Y166
L
R
T
A
R
A
G
Y
R
G
R
A
L
D
Y
Site 11
T201
R
L
V
E
A
Q
A
T
H
F
Q
Q
G
H
E
Site 12
S211
Q
Q
G
H
E
E
L
S
R
L
S
Q
Y
R
K
Site 13
S214
H
E
E
L
S
R
L
S
Q
Y
R
K
E
L
G
Site 14
S231
L
H
Q
L
V
L
N
S
A
R
E
K
R
D
M
Site 15
S258
G
G
E
E
P
E
P
S
L
R
E
G
P
G
G
Site 16
S277
G
H
L
F
K
R
A
S
N
A
F
K
T
W
S
Site 17
Y297
I
Q
S
N
Q
L
V
Y
Q
K
K
Y
K
D
P
Site 18
Y301
Q
L
V
Y
Q
K
K
Y
K
D
P
V
T
V
V
Site 19
T306
K
K
Y
K
D
P
V
T
V
V
V
D
D
L
R
Site 20
S323
T
V
K
L
C
P
D
S
E
R
R
F
C
F
E
Site 21
S333
R
F
C
F
E
V
V
S
T
S
K
S
C
L
L
Site 22
S337
E
V
V
S
T
S
K
S
C
L
L
Q
A
D
S
Site 23
S364
S
S
I
A
S
A
F
S
Q
A
R
L
D
D
S
Site 24
S371
S
Q
A
R
L
D
D
S
P
R
G
P
G
Q
G
Site 25
S379
P
R
G
P
G
Q
G
S
G
H
L
A
I
G
S
Site 26
S386
S
G
H
L
A
I
G
S
A
A
T
L
G
S
G
Site 27
T389
L
A
I
G
S
A
A
T
L
G
S
G
G
M
A
Site 28
S449
Q
C
S
G
I
H
R
S
L
G
V
H
F
S
K
Site 29
S459
V
H
F
S
K
V
R
S
L
T
L
D
S
W
E
Site 30
T461
F
S
K
V
R
S
L
T
L
D
S
W
E
P
E
Site 31
S464
V
R
S
L
T
L
D
S
W
E
P
E
L
V
K
Site 32
S502
K
K
P
G
P
S
C
S
R
Q
E
K
E
A
W
Site 33
Y514
E
A
W
I
H
A
K
Y
V
E
K
K
F
L
T
Site 34
T521
Y
V
E
K
K
F
L
T
K
L
P
E
I
R
G
Site 35
S547
P
P
V
P
P
K
P
S
I
R
P
R
P
G
S
Site 36
S554
S
I
R
P
R
P
G
S
L
R
S
K
P
E
P
Site 37
S557
P
R
P
G
S
L
R
S
K
P
E
P
P
S
E
Site 38
S563
R
S
K
P
E
P
P
S
E
D
L
G
S
L
H
Site 39
S568
P
P
S
E
D
L
G
S
L
H
P
G
A
L
L
Site 40
S584
R
A
S
G
H
P
P
S
L
P
T
M
A
D
A
Site 41
T609
N
G
G
Q
D
N
A
T
P
L
I
Q
A
T
A
Site 42
S638
A
N
V
N
Q
A
D
S
A
G
R
G
P
L
H
Site 43
T648
R
G
P
L
H
H
A
T
I
L
G
H
T
G
L
Site 44
S671
A
D
L
G
A
R
D
S
E
G
R
D
P
L
T
Site 45
T678
S
E
G
R
D
P
L
T
I
A
M
E
T
A
N
Site 46
T711
Q
G
Q
A
G
D
E
T
Y
L
D
I
F
R
D
Site 47
Y712
G
Q
A
G
D
E
T
Y
L
D
I
F
R
D
F
Site 48
S720
L
D
I
F
R
D
F
S
L
M
A
S
D
D
P
Site 49
S724
R
D
F
S
L
M
A
S
D
D
P
E
K
L
S
Site 50
S731
S
D
D
P
E
K
L
S
R
R
S
H
D
L
H
Site 51
S734
P
E
K
L
S
R
R
S
H
D
L
H
T
L
_
Site 52
T739
R
R
S
H
D
L
H
T
L
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation