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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TRAM2
Full Name:
Translocating chain-associated membrane protein 2
Alias:
KIAA0057; Tram2; Translocation associated membrane protein 2; Translocation-associated membrane protein 2
Type:
Membrane, Integral membrane protein
Mass (Da):
43328
Number AA:
370
UniProt ID:
Q15035
International Prot ID:
IPI00014218
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005789
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0032964
GO:0015031
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T7
_
M
A
F
R
R
R
T
K
S
Y
P
L
F
S
Site 2
S9
A
F
R
R
R
T
K
S
Y
P
L
F
S
Q
E
Site 3
Y10
F
R
R
R
T
K
S
Y
P
L
F
S
Q
E
F
Site 4
S14
T
K
S
Y
P
L
F
S
Q
E
F
V
I
H
N
Site 5
S57
I
L
P
Q
Y
N
I
S
V
P
T
A
D
S
E
Site 6
S63
I
S
V
P
T
A
D
S
E
T
V
H
Y
H
Y
Site 7
T65
V
P
T
A
D
S
E
T
V
H
Y
H
Y
G
P
Site 8
Y68
A
D
S
E
T
V
H
Y
H
Y
G
P
K
D
L
Site 9
S101
E
Y
I
L
D
K
I
S
K
R
L
H
L
S
K
Site 10
S107
I
S
K
R
L
H
L
S
K
V
K
H
S
K
F
Site 11
S112
H
L
S
K
V
K
H
S
K
F
N
E
S
G
Q
Site 12
T142
V
V
T
E
G
Y
L
T
N
P
R
S
L
W
E
Site 13
S146
G
Y
L
T
N
P
R
S
L
W
E
D
Y
P
H
Site 14
Y151
P
R
S
L
W
E
D
Y
P
H
V
H
L
P
F
Site 15
Y179
L
H
A
L
P
E
L
Y
F
Q
K
V
R
K
E
Site 16
Y235
F
H
T
A
R
L
F
Y
F
A
D
E
N
N
E
Site 17
Y321
Q
L
R
H
W
R
E
Y
W
N
E
Q
S
A
K
Site 18
S326
R
E
Y
W
N
E
Q
S
A
K
R
R
V
P
A
Site 19
T334
A
K
R
R
V
P
A
T
P
R
L
P
A
R
L
Site 20
S346
A
R
L
I
K
R
E
S
G
Y
H
E
N
G
V
Site 21
Y348
L
I
K
R
E
S
G
Y
H
E
N
G
V
V
K
Site 22
S361
V
K
A
E
N
G
T
S
P
R
T
K
K
L
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation