KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
LRRC14
Full Name:
Leucine-rich repeat-containing protein 14
Alias:
Type:
Mass (Da):
54513
Number AA:
493
UniProt ID:
Q15048
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S60
T
W
P
F
P
L
L
S
F
Q
Q
L
L
Q
E
Site 2
S81
A
L
L
Q
E
R
P
S
T
E
S
M
Q
A
V
Site 3
T82
L
L
Q
E
R
P
S
T
E
S
M
Q
A
V
I
Site 4
S84
Q
E
R
P
S
T
E
S
M
Q
A
V
I
L
G
Site 5
T98
G
L
T
A
R
L
H
T
S
E
P
G
A
S
T
Site 6
S104
H
T
S
E
P
G
A
S
T
Q
P
L
C
R
K
Site 7
S177
D
L
R
V
N
R
A
S
Y
A
F
L
R
E
A
Site 8
Y178
L
R
V
N
R
A
S
Y
A
F
L
R
E
A
L
Site 9
S187
F
L
R
E
A
L
R
S
S
V
G
S
P
L
R
Site 10
S188
L
R
E
A
L
R
S
S
V
G
S
P
L
R
L
Site 11
S252
A
R
F
Q
H
L
A
S
L
R
L
H
Y
V
H
Site 12
Y257
L
A
S
L
R
L
H
Y
V
H
G
D
S
R
Q
Site 13
S262
L
H
Y
V
H
G
D
S
R
Q
P
S
V
D
G
Site 14
S266
H
G
D
S
R
Q
P
S
V
D
G
E
D
N
F
Site 15
Y275
D
G
E
D
N
F
R
Y
F
L
A
Q
M
G
R
Site 16
S294
R
E
L
S
M
G
S
S
L
L
S
G
R
L
D
Site 17
S305
G
R
L
D
Q
L
L
S
T
L
Q
S
P
L
E
Site 18
T306
R
L
D
Q
L
L
S
T
L
Q
S
P
L
E
S
Site 19
S332
D
L
R
F
L
A
R
S
P
H
A
A
H
L
K
Site 20
S344
H
L
K
K
L
D
L
S
G
N
D
L
S
G
S
Site 21
S349
D
L
S
G
N
D
L
S
G
S
Q
L
A
P
F
Site 22
S351
S
G
N
D
L
S
G
S
Q
L
A
P
F
Q
G
Site 23
S417
L
K
E
L
L
R
D
S
V
A
Q
A
E
L
R
Site 24
Y435
H
P
F
P
V
D
C
Y
E
G
L
P
W
P
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation