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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
IQCB1
Full Name:
IQ calmodulin-binding motif-containing protein 1
Alias:
IQ motif containing B1; Nephrocystin-5; NPHP5; PIQ; SLSN5
Type:
Mass (Da):
68929
Number AA:
598
UniProt ID:
Q15051
International Prot ID:
IPI00014255
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005929
GO:0031513
GO:0032391
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005515
GO:0005516
PhosphoSite+
KinaseNET
Biological Process:
GO:0009987
GO:0019725
GO:0042592
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T4
_
_
_
_
M
K
P
T
G
T
D
P
R
I
L
Site 2
T6
_
_
M
K
P
T
G
T
D
P
R
I
L
S
I
Site 3
S12
G
T
D
P
R
I
L
S
I
A
A
E
V
A
K
Site 4
S20
I
A
A
E
V
A
K
S
P
E
Q
N
V
P
V
Site 5
Y54
K
K
I
K
Q
D
I
Y
C
Y
D
L
I
Q
Y
Site 6
S67
Q
Y
C
L
L
V
L
S
Q
D
Y
S
R
I
Q
Site 7
Y70
L
L
V
L
S
Q
D
Y
S
R
I
Q
G
G
W
Site 8
S71
L
V
L
S
Q
D
Y
S
R
I
Q
G
G
W
T
Site 9
S81
Q
G
G
W
T
T
I
S
Q
L
T
Q
I
L
S
Site 10
Y104
G
E
D
A
E
E
F
Y
N
E
L
L
P
S
A
Site 11
T252
L
I
L
L
R
Q
S
T
C
Y
K
G
L
R
R
Site 12
Y254
L
L
R
Q
S
T
C
Y
K
G
L
R
R
L
L
Site 13
S262
K
G
L
R
R
L
L
S
K
Q
E
T
G
T
E
Site 14
T266
R
L
L
S
K
Q
E
T
G
T
E
F
S
Q
E
Site 15
Y286
G
L
L
S
P
M
V
Y
Q
E
V
E
E
Q
K
Site 16
Y304
A
A
C
L
I
Q
A
Y
W
K
G
F
Q
T
R
Site 17
S319
K
R
L
K
K
L
P
S
A
V
I
A
L
Q
R
Site 18
S327
A
V
I
A
L
Q
R
S
F
R
S
K
R
S
K
Site 19
S330
A
L
Q
R
S
F
R
S
K
R
S
K
M
L
L
Site 20
S333
R
S
F
R
S
K
R
S
K
M
L
L
E
I
N
Site 21
S363
R
Q
R
A
M
R
L
S
R
E
L
Q
L
S
M
Site 22
Y383
P
G
Q
V
E
K
H
Y
R
E
M
E
E
K
S
Site 23
Y401
I
Q
K
H
W
R
G
Y
R
E
R
K
N
F
H
Site 24
S413
N
F
H
Q
Q
R
Q
S
L
I
E
Y
K
A
A
Site 25
Y417
Q
R
Q
S
L
I
E
Y
K
A
A
V
T
L
Q
Site 26
Y465
L
K
K
R
V
D
D
Y
V
R
R
H
L
G
S
Site 27
S472
Y
V
R
R
H
L
G
S
P
M
S
D
V
V
S
Site 28
S475
R
H
L
G
S
P
M
S
D
V
V
S
R
E
L
Site 29
S479
S
P
M
S
D
V
V
S
R
E
L
H
A
Q
A
Site 30
Y493
A
Q
E
R
L
Q
H
Y
F
M
G
R
A
L
E
Site 31
S526
E
Q
L
M
K
A
P
S
L
K
E
A
E
G
K
Site 32
S540
K
E
P
E
L
F
L
S
R
S
R
P
V
A
A
Site 33
S542
P
E
L
F
L
S
R
S
R
P
V
A
A
K
A
Site 34
S572
W
K
K
L
G
E
E
S
G
D
E
I
D
V
P
Site 35
S584
D
V
P
K
D
E
L
S
I
E
L
E
N
L
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation