PhosphoNET

           
Protein Info 
   
Short Name:  EIF4H
Full Name:  Eukaryotic translation initiation factor 4H
Alias:  EIF-4H; IF4H; KIAA0038; WBSCR1; Williams-Beuren syndrome chromosomal region 1 protein; Williams-Beuren syndrome chromosome region 1 protein; Williams-Beuren syndrome chromosome region 1 protein homolog; WSCR1
Type:  Translation protein, initiation complex
Mass (Da):  27385
Number AA:  248
UniProt ID:  Q15056
International Prot ID:  IPI00014263
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005829  GO:0016281 Uniprot OncoNet
Molecular Function:  GO:0000166  GO:0003676  GO:0003723 PhosphoSite+ KinaseNET
Biological Process:  GO:0006412  GO:0006417  GO:0006446 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1Y7_MADFDTYDDRAYSS
Site 2Y12DTYDDRAYSSFGGGR
Site 3S13TYDDRAYSSFGGGRG
Site 4S14YDDRAYSSFGGGRGS
Site 5S21SFGGGRGSRGSAGGH
Site 6S24GGRGSRGSAGGHGSR
Site 7S30GSAGGHGSRSQKELP
Site 8S32AGGHGSRSQKELPTE
Site 9T38RSQKELPTEPPYTAY
Site 10Y42ELPTEPPYTAYVGNL
Site 11T43LPTEPPYTAYVGNLP
Site 12Y45TEPPYTAYVGNLPFN
Site 13S69FKDLSIRSVRLVRDK
Site 14T78RLVRDKDTDKFKGFC
Site 15Y86DKFKGFCYVEFDEVD
Site 16S94VEFDEVDSLKEALTY
Site 17T100DSLKEALTYDGALLG
Site 18Y101SLKEALTYDGALLGD
Site 19S110GALLGDRSLRVDIAE
Site 20S140PDDRGMGSSRESRGG
Site 21S141DDRGMGSSRESRGGW
Site 22S144GMGSSRESRGGWDSR
Site 23S150ESRGGWDSRDDFNSG
Site 24S156DSRDDFNSGFRDDFL
Site 25S169FLGGRGGSRPGDRRT
Site 26T176SRPGDRRTGPPMGSR
Site 27S182RTGPPMGSRFRDGPP
Site 28S193DGPPLRGSNMDFREP
Site 29T201NMDFREPTEEERAQR
Site 30T217RLQLKPRTVATPLNQ
Site 31T220LKPRTVATPLNQVAN
Site 32S230NQVANPNSAIFGGAR
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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