PhosphoNET

           
Protein Info 
   
Short Name:  BRD3
Full Name:  Bromodomain-containing protein 3
Alias:  KIAA0043; RING3L; RING3-like protein
Type:  Protein-serine kinase, Atypical group, BRD family
Mass (Da):  79542
Number AA:  726
UniProt ID:  Q15059
International Prot ID:  IPI00014266
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634  GO:0043226  GO:0043227 Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T15APAGIPATPGPVNPP
Site 2S27NPPPPEVSNPSKPGR
Site 3S30PPEVSNPSKPGRKTN
Site 4T36PSKPGRKTNQLQYMQ
Site 5Y60HQFAWPFYQPVDAIK
Site 6Y73IKLNLPDYHKIIKNP
Site 7T85KNPMDMGTIKKRLEN
Site 8Y94KKRLENNYYWSASEC
Site 9Y95KRLENNYYWSASECM
Site 10T181VSSVSPATPFQSVPP
Site 11S185SPATPFQSVPPTVSQ
Site 12T248GVKRKADTTTPTTSA
Site 13T249VKRKADTTTPTTSAI
Site 14T250KRKADTTTPTTSAIT
Site 15S254DTTTPTTSAITASRS
Site 16T257TPTTSAITASRSESP
Site 17S259TTSAITASRSESPPP
Site 18S261SAITASRSESPPPLS
Site 19S263ITASRSESPPPLSDP
Site 20S268SESPPPLSDPKQAKV
Site 21S281KVVARRESGGRPIKP
Site 22S309AGKKGKLSEHLRYCD
Site 23Y314KLSEHLRYCDSILRE
Site 24S317EHLRYCDSILREMLS
Site 25S324SILREMLSKKHAAYA
Site 26Y330LSKKHAAYAWPFYKP
Site 27Y335AAYAWPFYKPVDAEA
Site 28Y348EALELHDYHDIIKHP
Site 29S359IKHPMDLSTVKRKMD
Site 30T360KHPMDLSTVKRKMDG
Site 31Y370RKMDGREYPDAQGFA
Site 32Y388RLMFSNCYKYNPPDH
Site 33Y390MFSNCYKYNPPDHEV
Site 34S434APAAPMVSKGAESSR
Site 35S439MVSKGAESSRSSEES
Site 36S440VSKGAESSRSSEESS
Site 37S442KGAESSRSSEESSSD
Site 38S443GAESSRSSEESSSDS
Site 39S446SSRSSEESSSDSGSS
Site 40S447SRSSEESSSDSGSSD
Site 41S448RSSEESSSDSGSSDS
Site 42S450SEESSSDSGSSDSEE
Site 43S452ESSSDSGSSDSEEER
Site 44S453SSSDSGSSDSEEERA
Site 45S455SDSGSSDSEEERATR
Site 46T461DSEEERATRLAELQE
Site 47S481HEQLAALSQAPVNKP
Site 48S558KKGGKQASASYDSEE
Site 49S560GGKQASASYDSEEEE
Site 50S563QASASYDSEEEEEGL
Site 51S573EEEGLPMSYDEKRQL
Site 52S581YDEKRQLSLDINRLP
Site 53S601RVVHIIQSREPSLRD
Site 54S605IIQSREPSLRDSNPD
Site 55S609REPSLRDSNPDEIEI
Site 56T620EIEIDFETLKPTTLR
Site 57T625FETLKPTTLRELERY
Site 58Y632TLRELERYVKSCLQK
Site 59S635ELERYVKSCLQKKQR
Site 60S646KKQRKPFSASGKKQA
Site 61S656GKKQAAKSKEELAQE
Site 62S676EKRLQDVSGQLSSSK
Site 63S680QDVSGQLSSSKKPAR
Site 64S682VSGQLSSSKKPARKE
Site 65S693ARKEKPGSAPSGGPS
Site 66S696EKPGSAPSGGPSRLS
Site 67S700SAPSGGPSRLSSSSS
Site 68S703SGGPSRLSSSSSSES
Site 69S704GGPSRLSSSSSSESG
Site 70S705GPSRLSSSSSSESGS
Site 71S706PSRLSSSSSSESGSS
Site 72S707SRLSSSSSSESGSSS
Site 73S708RLSSSSSSESGSSSS
Site 74S710SSSSSSESGSSSSSG
Site 75S712SSSSESGSSSSSGSS
Site 76S713SSSESGSSSSSGSSS
Site 77S714SSESGSSSSSGSSSD
Site 78S715SESGSSSSSGSSSDS
Site 79S716ESGSSSSSGSSSDSS
Site 80S718GSSSSSGSSSDSSDS
Site 81S719SSSSSGSSSDSSDSE
Site 82S720SSSSGSSSDSSDSE_
Site 83S722SSGSSSDSSDSE___
Site 84S723SGSSSDSSDSE____
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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