KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
WDR43
Full Name:
WD repeat-containing protein 43
Alias:
KIAA0007; NET12; WD repeat domain 43
Type:
Uncharacterized protein
Mass (Da):
74891
Number AA:
677
UniProt ID:
Q15061
International Prot ID:
IPI00055954
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y28
F
S
P
H
S
Q
A
Y
F
A
L
A
S
T
D
Site 2
Y52
N
N
R
L
H
Q
E
Y
V
P
S
A
H
L
S
Site 3
S55
L
H
Q
E
Y
V
P
S
A
H
L
S
G
T
C
Site 4
S77
A
R
L
Q
A
K
E
S
P
Q
R
K
K
R
K
Site 5
S85
P
Q
R
K
K
R
K
S
E
A
V
G
M
S
N
Site 6
S118
T
V
K
G
E
L
H
S
K
L
I
S
G
G
H
Site 7
S122
E
L
H
S
K
L
I
S
G
G
H
D
N
R
V
Site 8
Y142
H
Q
D
S
G
C
L
Y
S
C
S
D
D
K
H
Site 9
S143
Q
D
S
G
C
L
Y
S
C
S
D
D
K
H
I
Site 10
S145
S
G
C
L
Y
S
C
S
D
D
K
H
I
V
E
Site 11
S169
C
K
W
K
G
D
N
S
S
V
S
S
L
C
I
Site 12
S170
K
W
K
G
D
N
S
S
V
S
S
L
C
I
S
Site 13
S172
K
G
D
N
S
S
V
S
S
L
C
I
S
P
D
Site 14
S173
G
D
N
S
S
V
S
S
L
C
I
S
P
D
G
Site 15
S185
P
D
G
K
M
L
L
S
A
G
R
T
I
K
L
Site 16
T189
M
L
L
S
A
G
R
T
I
K
L
W
V
L
E
Site 17
T197
I
K
L
W
V
L
E
T
K
E
V
Y
R
H
F
Site 18
Y201
V
L
E
T
K
E
V
Y
R
H
F
T
G
H
A
Site 19
T205
K
E
V
Y
R
H
F
T
G
H
A
T
P
V
S
Site 20
T209
R
H
F
T
G
H
A
T
P
V
S
S
L
M
F
Site 21
T217
P
V
S
S
L
M
F
T
T
I
R
P
P
N
E
Site 22
T218
V
S
S
L
M
F
T
T
I
R
P
P
N
E
S
Site 23
S225
T
I
R
P
P
N
E
S
Q
P
F
D
G
I
T
Site 24
S259
R
S
E
N
K
E
K
S
A
V
M
S
F
T
V
Site 25
S263
K
E
K
S
A
V
M
S
F
T
V
T
D
E
P
Site 26
Y272
T
V
T
D
E
P
V
Y
I
D
L
T
L
S
E
Site 27
T276
E
P
V
Y
I
D
L
T
L
S
E
N
K
E
E
Site 28
S278
V
Y
I
D
L
T
L
S
E
N
K
E
E
P
V
Site 29
T321
N
C
T
I
Q
I
A
T
P
G
K
G
K
K
S
Site 30
S328
T
P
G
K
G
K
K
S
T
P
K
P
I
P
I
Site 31
T329
P
G
K
G
K
K
S
T
P
K
P
I
P
I
L
Site 32
T358
Y
G
S
W
F
Q
P
T
I
E
R
V
A
L
N
Site 33
S366
I
E
R
V
A
L
N
S
R
E
P
H
M
C
L
Site 34
T390
P
K
V
E
T
A
I
T
K
V
R
T
P
V
M
Site 35
T394
T
A
I
T
K
V
R
T
P
V
M
N
S
E
A
Site 36
S399
V
R
T
P
V
M
N
S
E
A
K
V
L
V
P
Site 37
T422
I
K
P
A
P
P
Q
T
E
Q
V
E
S
K
R
Site 38
S427
P
Q
T
E
Q
V
E
S
K
R
K
S
G
G
N
Site 39
S431
Q
V
E
S
K
R
K
S
G
G
N
E
V
S
I
Site 40
S437
K
S
G
G
N
E
V
S
I
E
E
R
L
G
A
Site 41
T449
L
G
A
M
D
I
D
T
H
K
K
G
K
E
D
Site 42
T459
K
G
K
E
D
L
Q
T
N
S
F
P
V
L
L
Site 43
S461
K
E
D
L
Q
T
N
S
F
P
V
L
L
T
Q
Site 44
T467
N
S
F
P
V
L
L
T
Q
G
L
E
S
N
D
Site 45
T510
I
P
L
L
Q
E
L
T
K
R
L
Q
G
H
P
Site 46
T561
L
M
E
S
R
V
K
T
F
Q
K
L
S
H
L
Site 47
S582
L
I
T
Q
V
T
A
S
E
K
T
K
G
A
T
Site 48
S590
E
K
T
K
G
A
T
S
P
G
Q
K
A
K
L
Site 49
Y599
G
Q
K
A
K
L
V
Y
E
E
E
S
S
E
E
Site 50
S603
K
L
V
Y
E
E
E
S
S
E
E
E
S
D
D
Site 51
S604
L
V
Y
E
E
E
S
S
E
E
E
S
D
D
E
Site 52
S608
E
E
S
S
E
E
E
S
D
D
E
I
A
D
K
Site 53
S617
D
E
I
A
D
K
D
S
E
D
N
W
D
E
D
Site 54
S628
W
D
E
D
E
E
E
S
E
S
E
K
D
E
D
Site 55
S630
E
D
E
E
E
S
E
S
E
K
D
E
D
V
E
Site 56
T656
E
N
G
E
D
R
D
T
A
S
E
K
E
L
N
Site 57
S658
G
E
D
R
D
T
A
S
E
K
E
L
N
G
D
Site 58
S666
E
K
E
L
N
G
D
S
D
L
D
P
E
N
E
Site 59
S674
D
L
D
P
E
N
E
S
E
E
E
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation