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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ACOX1
Full Name:
Peroxisomal acyl-coenzyme A oxidase 1
Alias:
ACOX; Acyl-Coenzyme A oxidase 1, palmitoyl; Acyl-coenzyme A oxidase 1, peroxisomal; AOX; PALMCOX; Palmitoyl-CoA oxidase; SCOX; Straight-chain acyl-CoA oxidase
Type:
EC 1.3.3.6; Lipid Metabolism - unsaturated fatty acid biosynthesis; Lipid Metabolism - fatty acid; Oxidoreductase; Lipid Metabolism - alpha-linolenic acid
Mass (Da):
74424
Number AA:
660
UniProt ID:
Q15067
International Prot ID:
IPI00296907
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005777
GO:0005777
GO:0005778
Uniprot
OncoNet
Molecular Function:
GO:0050660
GO:0003995
GO:0003997
PhosphoSite+
KinaseNET
Biological Process:
GO:0033540
GO:0006091
GO:0055114
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
D
L
R
R
E
R
D
S
A
S
F
N
P
E
L
Site 2
S13
R
R
E
R
D
S
A
S
F
N
P
E
L
L
T
Site 3
T20
S
F
N
P
E
L
L
T
H
I
L
D
G
S
P
Site 4
S26
L
T
H
I
L
D
G
S
P
E
K
T
R
R
R
Site 5
T30
L
D
G
S
P
E
K
T
R
R
R
R
E
I
E
Site 6
S57
D
L
N
F
L
T
R
S
Q
R
Y
E
V
A
V
Site 7
S126
Q
K
E
K
W
L
L
S
S
K
G
L
Q
I
I
Site 8
T135
K
G
L
Q
I
I
G
T
Y
A
Q
T
E
M
G
Site 9
T153
H
L
R
G
L
E
T
T
A
T
Y
D
P
E
T
Site 10
T155
R
G
L
E
T
T
A
T
Y
D
P
E
T
Q
E
Site 11
T160
T
A
T
Y
D
P
E
T
Q
E
F
I
L
N
S
Site 12
S167
T
Q
E
F
I
L
N
S
P
T
V
T
S
I
K
Site 13
T171
I
L
N
S
P
T
V
T
S
I
K
W
W
P
G
Site 14
Y200
L
I
T
K
G
K
C
Y
G
L
H
A
F
I
V
Site 15
T214
V
P
I
R
E
I
G
T
H
K
P
L
P
G
I
Site 16
T222
H
K
P
L
P
G
I
T
V
G
D
I
G
P
K
Site 17
Y232
D
I
G
P
K
F
G
Y
D
E
I
D
N
G
Y
Site 18
Y239
Y
D
E
I
D
N
G
Y
L
K
M
D
N
H
R
Site 19
Y256
R
E
N
M
L
M
K
Y
A
Q
V
K
P
D
G
Site 20
Y265
Q
V
K
P
D
G
T
Y
V
K
P
L
S
N
K
Site 21
S270
G
T
Y
V
K
P
L
S
N
K
L
T
Y
G
T
Site 22
Y275
P
L
S
N
K
L
T
Y
G
T
M
V
F
V
R
Site 23
S304
C
T
I
A
I
R
Y
S
A
V
R
H
Q
S
E
Site 24
S310
Y
S
A
V
R
H
Q
S
E
I
K
P
G
E
P
Site 25
T326
P
Q
I
L
D
F
Q
T
Q
Q
Y
K
L
F
P
Site 26
Y347
A
F
Q
F
V
G
A
Y
M
K
E
T
Y
H
R
Site 27
Y352
G
A
Y
M
K
E
T
Y
H
R
I
N
E
G
I
Site 28
S365
G
I
G
Q
G
D
L
S
E
L
P
E
L
H
A
Site 29
Y401
M
A
C
G
G
H
G
Y
S
H
C
S
G
L
P
Site 30
T415
P
N
I
Y
V
N
F
T
P
S
C
T
F
E
G
Site 31
T419
V
N
F
T
P
S
C
T
F
E
G
E
N
T
V
Site 32
S438
T
A
R
F
L
M
K
S
Y
D
Q
V
H
S
G
Site 33
Y439
A
R
F
L
M
K
S
Y
D
Q
V
H
S
G
K
Site 34
S460
S
Y
L
N
D
L
P
S
Q
R
I
Q
P
Q
Q
Site 35
S479
P
T
M
V
D
I
N
S
P
E
S
L
T
E
A
Site 36
S482
V
D
I
N
S
P
E
S
L
T
E
A
Y
K
L
Site 37
Y487
P
E
S
L
T
E
A
Y
K
L
R
A
A
R
L
Site 38
S511
K
E
V
I
H
R
K
S
K
E
V
A
W
N
L
Site 39
S527
S
V
D
L
V
R
A
S
E
A
H
C
H
Y
V
Site 40
T586
I
M
T
E
P
Q
I
T
Q
V
N
Q
R
V
K
Site 41
T597
Q
R
V
K
E
L
L
T
L
I
R
S
D
A
V
Site 42
S619
F
Q
D
V
T
L
G
S
V
L
G
R
Y
D
G
Site 43
Y624
L
G
S
V
L
G
R
Y
D
G
N
V
Y
E
N
Site 44
Y629
G
R
Y
D
G
N
V
Y
E
N
L
F
E
W
A
Site 45
S639
L
F
E
W
A
K
N
S
P
L
N
K
A
E
V
Site 46
S649
N
K
A
E
V
H
E
S
Y
K
H
L
K
S
L
Site 47
S655
E
S
Y
K
H
L
K
S
L
Q
S
K
L
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation