PhosphoNET

           
Protein Info 
   
Short Name:  PPP2R5B
Full Name:  Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform
Alias:  2A5B; B56B; B56beta; Beta isoform of regulatory subunit B56, protein phosphatase 2A; FLJ35411; PP2A B subunit B' beta; PP2A B subunit B56 beta; PP2A, B subunit, B' beta; PP2A, B subunit, B56 beta; PP2A, B subunit, B56 beta isoform; PP2A, B subunit, PR61 beta; PP2A, B subunit, PR61 beta isoform; PP2A, B subunit, R5 beta; PP2A, B subunit, R5 beta isoform; PP2A, B, B' beta; PR61B; Protein phosphatase 2, regulatory subunit B (B56), beta; Serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, beta; Serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, beta isoform; Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta
Type:  Protein phosphatase, regulatory subunit
Mass (Da):  57393
Number AA:  497
UniProt ID:  Q15173
International Prot ID:  IPI00014980
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0000159   Uniprot OncoNet
Molecular Function:  GO:0005515  GO:0008601   PhosphoSite+ KinaseNET
Biological Process:  GO:0007165     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S9ETKLPPASTPTSPSS
Site 2T10TKLPPASTPTSPSSP
Site 3T12LPPASTPTSPSSPGL
Site 4S13PPASTPTSPSSPGLS
Site 5S15ASTPTSPSSPGLSPV
Site 6S16STPTSPSSPGLSPVP
Site 7S20SPSSPGLSPVPPPDK
Site 8S32PDKVDGFSRRSLRRA
Site 9S35VDGFSRRSLRRARPR
Site 10S44RRARPRRSHSSSQFR
Site 11S46ARPRRSHSSSQFRYQ
Site 12S47RPRRSHSSSQFRYQS
Site 13S48PRRSHSSSQFRYQSN
Site 14Y52HSSSQFRYQSNQQEL
Site 15S54SSQFRYQSNQQELTP
Site 16T60QSNQQELTPLPLLKD
Site 17S78SELHELLSRKLAQCG
Site 18Y126GVLIEPVYPDIIRMI
Site 19T140ISVNIFRTLPPSENP
Site 20S144IFRTLPPSENPEFDP
Site 21S161DEPNLEPSWPHLQLV
Site 22S184ESPDFQPSVAKRYVD
Site 23Y189QPSVAKRYVDQKFVL
Site 24S204MLLELFDSEDPRERE
Site 25Y212EDPREREYLKTILHR
Site 26T215REREYLKTILHRVYG
Site 27Y221KTILHRVYGKFLGLR
Site 28Y230KFLGLRAYIRKQCNH
Site 29Y244HIFLRFIYEFEHFNG
Site 30T311QFLEKDATLTEHVIR
Site 31Y323VIRGLLKYWPKTCTQ
Site 32S367KQVARCVSSPHFQVA
Site 33S368QVARCVSSPHFQVAE
Site 34Y379QVAERALYFWNNEYI
Site 35Y406PAVFGTLYQVSKEHW
Site 36T440GKLFDELTASYKLEK
Site 37S442LFDELTASYKLEKQQ
Site 38T475RLRRLQGTQGAKEAP
Site 39T487EAPLQRLTPQVAASG
Site 40S493LTPQVAASGGQS___
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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