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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PTGES3
Full Name:
Prostaglandin E synthase 3
Alias:
CPGES; Cytosolic prostaglandin E2 synthase; TEBP
Type:
Chaperone protein
Mass (Da):
18697
Number AA:
160
UniProt ID:
Q15185
International Prot ID:
IPI00015029
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0000781
GO:0005697
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0003720
GO:0003824
GO:0003964
PhosphoSite+
KinaseNET
Biological Process:
GO:0000723
GO:0001516
GO:0006082
Phosida
TranscriptoNet
STRING
Kinexus Products
Prostaglandin E synthase 3 pan-specific antibody AB-NN309-1#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN309-1
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y9
Q
P
A
S
A
K
W
Y
D
R
R
D
Y
V
F
Site 2
Y14
K
W
Y
D
R
R
D
Y
V
F
I
E
F
C
V
Site 3
T37
N
F
E
K
S
K
L
T
F
S
C
L
G
G
S
Site 4
S39
E
K
S
K
L
T
F
S
C
L
G
G
S
D
N
Site 5
S44
T
F
S
C
L
G
G
S
D
N
F
K
H
L
N
Site 6
T69
N
D
S
K
H
K
R
T
D
R
S
I
L
C
C
Site 7
S72
K
H
K
R
T
D
R
S
I
L
C
C
L
R
K
Site 8
S82
C
C
L
R
K
G
E
S
G
Q
S
W
P
R
L
Site 9
S85
R
K
G
E
S
G
Q
S
W
P
R
L
T
K
E
Site 10
T90
G
Q
S
W
P
R
L
T
K
E
R
A
K
L
N
Site 11
S100
R
A
K
L
N
W
L
S
V
D
F
N
N
W
K
Site 12
S113
W
K
D
W
E
D
D
S
D
E
D
M
S
N
F
Site 13
S118
D
D
S
D
E
D
M
S
N
F
D
R
F
S
E
Site 14
S124
M
S
N
F
D
R
F
S
E
M
M
N
N
M
G
Site 15
S148
V
D
G
A
D
D
D
S
Q
D
S
D
D
E
K
Site 16
S151
A
D
D
D
S
Q
D
S
D
D
E
K
M
P
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation