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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NONO
Full Name:
Non-POU domain-containing octamer-binding protein
Alias:
54 kDa nuclear RNA-and DNA-binding protein; 55 kDa nuclear protein; DNA-binding p52/p100 complex, 52 kDa subunit; NMT55; Non-POU domain containing, octamer-binding; Non-Pou domain-containing octamer (ATGCAAAT) binding protein; Non-POU-domain-containing, octamer-binding; Nrb; NRB54; Nuclear RNA-binding protein, 54-kD; P54; P54nrb
Type:
Nuclear receptor co-regulator; RNA binding protein
Mass (Da):
54232
Number AA:
471
UniProt ID:
Q15233
International Prot ID:
IPI00304596
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0003723
GO:0042802
PhosphoSite+
KinaseNET
Biological Process:
GO:0006310
GO:0006281
GO:0008380
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T15
N
L
E
K
Q
N
H
T
P
R
K
H
H
Q
H
Site 2
S50
A
N
G
Q
Q
A
S
S
Q
N
E
G
L
T
I
Site 3
T69
F
R
K
P
G
E
K
T
F
T
Q
R
S
R
L
Site 4
T71
K
P
G
E
K
T
F
T
Q
R
S
R
L
F
V
Site 5
T86
G
N
L
P
P
D
I
T
E
E
E
M
R
K
L
Site 6
Y97
M
R
K
L
F
E
K
Y
G
K
A
G
E
V
F
Site 7
S147
R
V
R
F
A
C
H
S
A
S
L
T
V
R
N
Site 8
S149
R
F
A
C
H
S
A
S
L
T
V
R
N
L
P
Site 9
T151
A
C
H
S
A
S
L
T
V
R
N
L
P
Q
Y
Site 10
Y158
T
V
R
N
L
P
Q
Y
V
S
N
E
L
L
E
Site 11
S160
R
N
L
P
Q
Y
V
S
N
E
L
L
E
E
A
Site 12
S169
E
L
L
E
E
A
F
S
V
F
G
Q
V
E
R
Site 13
S188
V
D
D
R
G
R
P
S
G
K
G
I
V
E
F
Site 14
S209
R
K
A
L
D
R
C
S
E
G
S
F
L
L
T
Site 15
T216
S
E
G
S
F
L
L
T
T
F
P
R
P
V
T
Site 16
T223
T
T
F
P
R
P
V
T
V
E
P
M
D
Q
L
Site 17
S262
P
R
F
A
Q
P
G
S
F
E
Y
E
Y
A
M
Site 18
Y265
A
Q
P
G
S
F
E
Y
E
Y
A
M
R
W
K
Site 19
Y267
P
G
S
F
E
Y
E
Y
A
M
R
W
K
A
L
Site 20
T410
P
A
P
V
P
A
G
T
P
A
P
P
G
P
A
Site 21
T418
P
A
P
P
G
P
A
T
M
M
P
D
G
T
L
Site 22
T424
A
T
M
M
P
D
G
T
L
G
L
T
P
P
T
Site 23
T428
P
D
G
T
L
G
L
T
P
P
T
T
E
R
F
Site 24
T431
T
L
G
L
T
P
P
T
T
E
R
F
G
Q
A
Site 25
T432
L
G
L
T
P
P
T
T
E
R
F
G
Q
A
A
Site 26
T440
E
R
F
G
Q
A
A
T
M
E
G
I
G
A
I
Site 27
T450
G
I
G
A
I
G
G
T
P
P
A
F
N
R
A
Site 28
Y471
A
P
N
K
R
R
R
Y
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation