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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PTPRR
Full Name:
Receptor-type tyrosine-protein phosphatase R
Alias:
Ch-1PTPase; EC 3.1.3.48; ECPTP; NC-PTPCOM1; PCPTP1; PTP-SL
Type:
Protein-tyrosine phosphatase, receptor
Mass (Da):
73834
Number AA:
657
UniProt ID:
Q15256
International Prot ID:
IPI00033560
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0009986
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0019901
GO:0005001
PhosphoSite+
KinaseNET
Biological Process:
GO:0001701
GO:0006470
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y44
S
G
K
P
V
F
I
Y
K
H
S
Q
D
I
E
Site 2
Y62
D
I
A
P
Q
K
I
Y
R
H
S
Y
H
S
S
Site 3
S258
L
K
E
R
F
Q
L
S
L
R
Q
D
K
E
K
Site 4
S272
K
N
Q
E
I
H
L
S
P
I
T
L
Q
P
A
Site 5
S281
I
T
L
Q
P
A
L
S
E
A
K
T
V
H
S
Site 6
T285
P
A
L
S
E
A
K
T
V
H
S
M
V
Q
P
Site 7
S324
T
A
T
S
V
C
P
S
P
F
K
M
K
P
I
Site 8
S339
G
L
Q
E
R
R
G
S
N
V
S
L
T
L
D
Site 9
S342
E
R
R
G
S
N
V
S
L
T
L
D
M
S
S
Site 10
T344
R
G
S
N
V
S
L
T
L
D
M
S
S
L
G
Site 11
S358
G
N
I
E
P
F
V
S
I
P
T
P
R
E
K
Site 12
T361
E
P
F
V
S
I
P
T
P
R
E
K
V
A
M
Site 13
Y370
R
E
K
V
A
M
E
Y
L
Q
S
A
S
R
I
Site 14
T379
Q
S
A
S
R
I
L
T
R
S
Q
L
R
D
V
Site 15
S381
A
S
R
I
L
T
R
S
Q
L
R
D
V
V
A
Site 16
S389
Q
L
R
D
V
V
A
S
S
H
L
L
Q
S
E
Site 17
S395
A
S
S
H
L
L
Q
S
E
F
M
E
I
P
M
Site 18
T417
I
D
I
P
R
H
G
T
K
N
R
Y
K
T
I
Site 19
Y421
R
H
G
T
K
N
R
Y
K
T
I
L
P
N
P
Site 20
T423
G
T
K
N
R
Y
K
T
I
L
P
N
P
L
S
Site 21
S430
T
I
L
P
N
P
L
S
R
V
C
L
R
P
K
Site 22
T440
C
L
R
P
K
N
V
T
D
S
L
S
T
Y
I
Site 23
S442
R
P
K
N
V
T
D
S
L
S
T
Y
I
N
A
Site 24
S444
K
N
V
T
D
S
L
S
T
Y
I
N
A
N
Y
Site 25
Y446
V
T
D
S
L
S
T
Y
I
N
A
N
Y
I
R
Site 26
Y451
S
T
Y
I
N
A
N
Y
I
R
G
Y
S
G
K
Site 27
Y455
N
A
N
Y
I
R
G
Y
S
G
K
E
K
A
F
Site 28
S456
A
N
Y
I
R
G
Y
S
G
K
E
K
A
F
I
Site 29
Y504
K
N
E
K
C
V
L
Y
W
P
E
K
R
G
I
Site 30
Y512
W
P
E
K
R
G
I
Y
G
K
V
E
V
L
V
Site 31
Y528
S
V
N
E
C
D
N
Y
T
I
R
N
L
V
L
Site 32
T529
V
N
E
C
D
N
Y
T
I
R
N
L
V
L
K
Site 33
T557
T
S
W
P
D
H
K
T
P
D
S
A
Q
P
L
Site 34
S560
P
D
H
K
T
P
D
S
A
Q
P
L
L
Q
L
Site 35
S578
V
E
E
D
R
L
A
S
Q
G
R
G
P
V
V
Site 36
Y647
V
H
H
A
L
C
L
Y
E
S
R
L
S
A
E
Site 37
S652
C
L
Y
E
S
R
L
S
A
E
T
V
Q
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation