PhosphoNET

           
Protein Info 
   
Short Name:  NKX1-1
Full Name:  NK1 transcription factor-related protein 1
Alias:  Homeobox protein 153;Homeobox protein SAX-2;NKX-1.1
Type: 
Mass (Da):  40659
Number AA:  411
UniProt ID:  Q15270
International Prot ID: 
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:      Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1T23PPLAASDTVPAAPEG
Site 2S58LDPNKFNSRRRRCVL
Site 3S89CAPAPAASGRPPRAE
Site 4T133GEAETNDTNGYSSGG
Site 5Y136ETNDTNGYSSGGGGH
Site 6S137TNDTNGYSSGGGGHS
Site 7S138NDTNGYSSGGGGHSP
Site 8S144SSGGGGHSPSADSGD
Site 9S146GGGGHSPSADSGDEV
Site 10S149GHSPSADSGDEVPDD
Site 11T167DEDEAPETEAARGAE
Site 12S188GGLGARGSGCQGAAE
Site 13S199GAAETDASPGATVDE
Site 14T203TDASPGATVDEAAAP
Site 15S216APGPRENSPVAQGPP
Site 16T235APGGAGTTPQGTATA
Site 17T250AKPKRKRTGSDSKSG
Site 18S252PKRKRTGSDSKSGKP
Site 19S254RKRTGSDSKSGKPRR
Site 20S256RTGSDSKSGKPRRAR
Site 21T264GKPRRARTAFTYEQL
Site 22Y268RARTAFTYEQLVALE
Site 23Y283NKFKATRYLSVCERL
Site 24S285FKATRYLSVCERLNL
Site 25S295ERLNLALSLSLTETQ
Site 26T323KQNPGADTSAPTGGG
Site 27S324QNPGADTSAPTGGGG
Site 28T341GPGAGPGTGLPGGLS
Site 29S348TGLPGGLSPLSPSPP
Site 30S351PGGLSPLSPSPPMGA
Site 31Y368GMHGPAGYPAHGPGG
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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