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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RABEP1
Full Name:
Rab GTPase-binding effector protein 1
Alias:
Neurocrescin; Rab GTPase binding effector protein 1; Rab5ep; Rabaptin, RAB GTPase binding effector protein 1; Rabaptin, RAB GTPase binding effector protein 1 (RABPT5); Rabaptin-4; Rabaptin-5; Rabaptin-5alpha; Rabe1; Rabep1; Rabpt5; Rabpt5a; Renal carcinoma antigen NY-REN-17
Type:
Vesicle protein
Mass (Da):
99290
Number AA:
862
UniProt ID:
Q15276
International Prot ID:
IPI00293009
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005769
GO:0055037
GO:0005769
Uniprot
OncoNet
Molecular Function:
GO:0005096
GO:0008083
GO:0005488
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
GO:0006897
GO:0006944
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
A
Q
P
G
P
A
S
Q
P
D
V
S
L
Q
Site 2
S13
P
A
S
Q
P
D
V
S
L
Q
Q
R
V
A
E
Site 3
Y50
R
A
K
F
K
E
L
Y
L
A
K
E
E
D
L
Site 4
T76
D
D
L
G
H
L
R
T
Q
L
W
E
A
Q
A
Site 5
S95
I
K
A
I
A
T
V
S
E
N
T
K
Q
E
A
Site 6
S116
Q
W
R
E
E
V
A
S
L
Q
A
V
M
K
E
Site 7
T124
L
Q
A
V
M
K
E
T
V
R
D
Y
E
H
Q
Site 8
Y128
M
K
E
T
V
R
D
Y
E
H
Q
F
H
L
R
Site 9
T141
L
R
L
E
Q
E
R
T
Q
W
A
Q
Y
R
E
Site 10
S149
Q
W
A
Q
Y
R
E
S
A
E
R
E
I
A
D
Site 11
S162
A
D
L
R
R
R
L
S
E
G
Q
E
E
E
N
Site 12
S186
E
D
A
E
K
L
R
S
V
V
M
P
M
E
K
Site 13
T203
A
A
L
K
D
K
L
T
E
A
E
D
K
I
K
Site 14
S215
K
I
K
E
L
E
A
S
K
V
K
E
L
N
H
Site 15
Y223
K
V
K
E
L
N
H
Y
L
E
A
E
K
S
C
Site 16
S229
H
Y
L
E
A
E
K
S
C
R
T
D
L
E
M
Site 17
S246
A
V
L
N
T
Q
K
S
V
L
Q
E
D
A
E
Site 18
S290
A
N
D
Q
F
L
E
S
Q
R
L
L
M
R
D
Site 19
T306
Q
R
M
E
I
V
L
T
S
E
Q
L
R
Q
V
Site 20
S357
C
A
L
T
Q
E
E
S
S
A
Q
L
S
N
E
Site 21
S362
E
E
S
S
A
Q
L
S
N
E
E
E
H
L
D
Site 22
S370
N
E
E
E
H
L
D
S
T
R
G
S
V
H
S
Site 23
T371
E
E
E
H
L
D
S
T
R
G
S
V
H
S
L
Site 24
S374
H
L
D
S
T
R
G
S
V
H
S
L
D
A
G
Site 25
S377
S
T
R
G
S
V
H
S
L
D
A
G
L
L
L
Site 26
S386
D
A
G
L
L
L
P
S
G
D
P
F
S
K
S
Site 27
S391
L
P
S
G
D
P
F
S
K
S
D
N
D
M
F
Site 28
S393
S
G
D
P
F
S
K
S
D
N
D
M
F
K
D
Site 29
S407
D
G
L
R
R
A
Q
S
T
D
S
L
G
T
S
Site 30
T408
G
L
R
R
A
Q
S
T
D
S
L
G
T
S
G
Site 31
S410
R
R
A
Q
S
T
D
S
L
G
T
S
G
S
L
Site 32
T413
Q
S
T
D
S
L
G
T
S
G
S
L
Q
S
K
Site 33
S414
S
T
D
S
L
G
T
S
G
S
L
Q
S
K
A
Site 34
S416
D
S
L
G
T
S
G
S
L
Q
S
K
A
L
G
Site 35
S419
G
T
S
G
S
L
Q
S
K
A
L
G
Y
N
Y
Site 36
Y426
S
K
A
L
G
Y
N
Y
K
A
K
S
A
G
N
Site 37
S430
G
Y
N
Y
K
A
K
S
A
G
N
L
D
E
S
Site 38
S437
S
A
G
N
L
D
E
S
D
F
G
P
L
V
G
Site 39
S447
G
P
L
V
G
A
D
S
V
S
E
N
F
D
T
Site 40
S449
L
V
G
A
D
S
V
S
E
N
F
D
T
A
S
Site 41
T454
S
V
S
E
N
F
D
T
A
S
L
G
S
L
Q
Site 42
S456
S
E
N
F
D
T
A
S
L
G
S
L
Q
M
P
Site 43
T480
E
R
A
I
K
A
M
T
P
E
Q
E
E
T
A
Site 44
T486
M
T
P
E
Q
E
E
T
A
S
L
L
S
S
V
Site 45
S488
P
E
Q
E
E
T
A
S
L
L
S
S
V
T
Q
Site 46
S492
E
T
A
S
L
L
S
S
V
T
Q
G
M
E
S
Site 47
S499
S
V
T
Q
G
M
E
S
A
Y
V
S
P
S
G
Site 48
Y501
T
Q
G
M
E
S
A
Y
V
S
P
S
G
Y
R
Site 49
S503
G
M
E
S
A
Y
V
S
P
S
G
Y
R
L
V
Site 50
S505
E
S
A
Y
V
S
P
S
G
Y
R
L
V
S
E
Site 51
Y507
A
Y
V
S
P
S
G
Y
R
L
V
S
E
T
E
Site 52
S511
P
S
G
Y
R
L
V
S
E
T
E
W
N
L
L
Site 53
T513
G
Y
R
L
V
S
E
T
E
W
N
L
L
Q
K
Site 54
Y539
R
C
D
M
C
S
N
Y
E
K
Q
L
Q
G
I
Site 55
T553
I
Q
I
Q
E
A
E
T
R
D
Q
V
K
K
L
Site 56
T574
A
N
D
Q
L
E
K
T
M
K
D
K
Q
E
L
Site 57
S588
L
E
D
F
I
K
Q
S
S
E
D
S
S
H
Q
Site 58
S589
E
D
F
I
K
Q
S
S
E
D
S
S
H
Q
I
Site 59
S592
I
K
Q
S
S
E
D
S
S
H
Q
I
S
A
L
Site 60
S593
K
Q
S
S
E
D
S
S
H
Q
I
S
A
L
V
Site 61
S597
E
D
S
S
H
Q
I
S
A
L
V
L
R
A
Q
Site 62
S618
E
E
L
Q
Q
G
L
S
Q
A
K
R
D
V
Q
Site 63
S651
R
L
Q
K
D
N
D
S
L
Q
G
K
H
S
L
Site 64
S657
D
S
L
Q
G
K
H
S
L
H
V
S
L
Q
Q
Site 65
S661
G
K
H
S
L
H
V
S
L
Q
Q
A
E
D
F
Site 66
T673
E
D
F
I
L
P
D
T
T
E
A
L
R
E
L
Site 67
S740
N
C
K
E
E
I
A
S
I
S
S
L
K
A
E
Site 68
S743
E
E
I
A
S
I
S
S
L
K
A
E
L
E
R
Site 69
S760
V
E
K
G
Q
L
E
S
T
L
R
E
K
S
Q
Site 70
T761
E
K
G
Q
L
E
S
T
L
R
E
K
S
Q
Q
Site 71
S766
E
S
T
L
R
E
K
S
Q
Q
L
E
S
L
Q
Site 72
S778
S
L
Q
E
I
K
I
S
L
E
E
Q
L
K
K
Site 73
T792
K
E
T
A
A
K
A
T
V
E
Q
L
M
F
E
Site 74
T809
N
K
A
Q
R
L
Q
T
E
L
D
V
S
E
Q
Site 75
S814
L
Q
T
E
L
D
V
S
E
Q
V
Q
R
D
F
Site 76
S825
Q
R
D
F
V
K
L
S
Q
T
L
Q
V
Q
L
Site 77
T827
D
F
V
K
L
S
Q
T
L
Q
V
Q
L
E
R
Site 78
S840
E
R
I
R
Q
A
D
S
L
E
R
I
R
A
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation