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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RBBP5
Full Name:
Retinoblastoma-binding protein 5
Alias:
RBBP-5; RBQ3; Retinoblastoma binding protein 5; Retinoblastoma-binding protein RBQ-3; SWD1; SWD1, Set1c WD40 repeat protein
Type:
Transcription, coactivator/corepressor
Mass (Da):
59153
Number AA:
538
UniProt ID:
Q15291
International Prot ID:
IPI00021035
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0035097
Uniprot
OncoNet
Molecular Function:
GO:0010843
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0051568
GO:0043627
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
N
L
E
L
L
E
S
F
G
Q
N
Y
P
E
Site 2
Y13
L
E
S
F
G
Q
N
Y
P
E
E
A
D
G
T
Site 3
T20
Y
P
E
E
A
D
G
T
L
D
C
I
S
M
A
Site 4
S91
A
S
T
D
N
I
V
S
Q
W
D
V
L
S
G
Site 5
S108
D
Q
R
F
R
F
P
S
P
I
L
K
V
Q
Y
Site 6
Y115
S
P
I
L
K
V
Q
Y
H
P
R
D
Q
N
K
Site 7
S130
V
L
V
C
P
M
K
S
A
P
V
M
L
T
L
Site 8
T136
K
S
A
P
V
M
L
T
L
S
D
S
K
H
V
Site 9
S138
A
P
V
M
L
T
L
S
D
S
K
H
V
V
L
Site 10
S158
S
D
L
N
V
V
A
S
F
D
R
R
G
E
Y
Site 11
Y165
S
F
D
R
R
G
E
Y
I
Y
T
G
N
A
K
Site 12
Y167
D
R
R
G
E
Y
I
Y
T
G
N
A
K
G
K
Site 13
T168
R
R
G
E
Y
I
Y
T
G
N
A
K
G
K
I
Site 14
S182
I
L
V
L
K
T
D
S
Q
D
L
V
A
S
F
Site 15
S188
D
S
Q
D
L
V
A
S
F
R
V
T
T
G
T
Site 16
T193
V
A
S
F
R
V
T
T
G
T
S
N
T
T
A
Site 17
T195
S
F
R
V
T
T
G
T
S
N
T
T
A
I
K
Site 18
T198
V
T
T
G
T
S
N
T
T
A
I
K
S
I
E
Site 19
S203
S
N
T
T
A
I
K
S
I
E
F
A
R
K
G
Site 20
Y225
A
D
R
I
I
R
V
Y
D
G
R
E
I
L
T
Site 21
Y265
C
F
S
G
D
G
E
Y
I
V
A
G
S
A
R
Site 22
S270
G
E
Y
I
V
A
G
S
A
R
Q
H
A
L
Y
Site 23
Y277
S
A
R
Q
H
A
L
Y
I
W
E
K
S
I
G
Site 24
Y345
E
L
D
E
N
V
E
Y
E
E
R
E
S
E
F
Site 25
S350
V
E
Y
E
E
R
E
S
E
F
D
I
E
D
E
Site 26
S360
D
I
E
D
E
D
K
S
E
P
E
Q
T
G
A
Site 27
T378
E
D
E
E
V
D
V
T
S
V
D
P
I
A
A
Site 28
S388
D
P
I
A
A
F
C
S
S
D
E
E
L
E
D
Site 29
S389
P
I
A
A
F
C
S
S
D
E
E
L
E
D
S
Site 30
S396
S
D
E
E
L
E
D
S
K
A
L
L
Y
L
P
Site 31
Y416
E
D
P
E
E
N
P
Y
G
P
P
P
D
A
V
Site 32
S426
P
P
D
A
V
Q
T
S
L
M
D
E
G
A
S
Site 33
S434
L
M
D
E
G
A
S
S
E
K
K
R
Q
S
S
Site 34
S440
S
S
E
K
K
R
Q
S
S
A
D
G
S
Q
P
Site 35
S441
S
E
K
K
R
Q
S
S
A
D
G
S
Q
P
P
Site 36
S445
R
Q
S
S
A
D
G
S
Q
P
P
K
K
K
P
Site 37
T454
P
P
K
K
K
P
K
T
T
N
I
E
L
Q
G
Site 38
S479
G
V
K
G
D
G
K
S
K
K
K
Q
A
G
R
Site 39
S490
Q
A
G
R
P
K
G
S
K
G
K
E
K
D
S
Site 40
S497
S
K
G
K
E
K
D
S
P
F
K
P
K
L
Y
Site 41
Y504
S
P
F
K
P
K
L
Y
K
G
D
R
G
L
P
Site 42
S515
R
G
L
P
L
E
G
S
A
K
G
K
V
Q
A
Site 43
S525
G
K
V
Q
A
E
L
S
Q
P
L
T
A
G
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation