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Updated November 2019
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Protein Info
Short Name:
MUF1
Full Name:
Leucine-rich repeat-containing protein 41
Alias:
Elongin BC-interacting leucine-rich repeat protein; Leucine rich repeat containing 41; LRC41; LRRC41
Type:
Ubiquitin conjugating system
Mass (Da):
88650
Number AA:
812
UniProt ID:
Q15345
International Prot ID:
IPI00397575
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0019941
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S36
E
A
A
P
A
K
S
S
A
S
G
P
N
A
P
Site 2
S38
A
P
A
K
S
S
A
S
G
P
N
A
P
P
A
Site 3
S98
T
A
L
K
K
G
L
S
T
Q
A
I
W
R
R
Site 4
T113
L
W
D
E
L
M
K
T
R
P
S
S
L
E
S
Site 5
S116
E
L
M
K
T
R
P
S
S
L
E
S
V
T
C
Site 6
S117
L
M
K
T
R
P
S
S
L
E
S
V
T
C
W
Site 7
S120
T
R
P
S
S
L
E
S
V
T
C
W
R
A
K
Site 8
T140
F
S
H
V
L
R
G
T
I
D
V
S
S
D
R
Site 9
S144
L
R
G
T
I
D
V
S
S
D
R
R
L
C
D
Site 10
S145
R
G
T
I
D
V
S
S
D
R
R
L
C
D
Q
Site 11
S155
R
L
C
D
Q
R
F
S
P
L
L
H
S
S
R
Site 12
S160
R
F
S
P
L
L
H
S
S
R
H
V
R
Q
L
Site 13
T168
S
R
H
V
R
Q
L
T
I
C
N
M
L
Q
G
Site 14
T190
P
N
R
R
V
L
E
T
L
A
S
S
L
H
T
Site 15
S206
K
F
R
H
L
L
F
S
D
V
A
A
Q
Q
S
Site 16
S213
S
D
V
A
A
Q
Q
S
L
R
Q
L
L
H
Q
Site 17
Y233
A
V
S
Q
V
S
L
Y
S
W
P
V
P
E
S
Site 18
S234
V
S
Q
V
S
L
Y
S
W
P
V
P
E
S
A
Site 19
S270
C
R
L
C
G
E
A
S
R
G
R
A
P
S
R
Site 20
S276
A
S
R
G
R
A
P
S
R
D
E
G
S
L
L
Site 21
S281
A
P
S
R
D
E
G
S
L
L
L
G
S
R
R
Site 22
S286
E
G
S
L
L
L
G
S
R
R
P
R
R
D
A
Site 23
S304
C
A
A
A
L
M
A
S
R
R
K
S
E
A
K
Site 24
S308
L
M
A
S
R
R
K
S
E
A
K
Q
M
P
R
Site 25
T320
M
P
R
A
A
P
A
T
R
V
T
R
R
S
T
Site 26
T323
A
A
P
A
T
R
V
T
R
R
S
T
Q
E
S
Site 27
S326
A
T
R
V
T
R
R
S
T
Q
E
S
L
T
A
Site 28
T327
T
R
V
T
R
R
S
T
Q
E
S
L
T
A
G
Site 29
S330
T
R
R
S
T
Q
E
S
L
T
A
G
G
T
D
Site 30
T347
R
E
L
H
P
P
A
T
S
H
E
A
P
G
T
Site 31
S348
E
L
H
P
P
A
T
S
H
E
A
P
G
T
K
Site 32
T354
T
S
H
E
A
P
G
T
K
R
S
P
S
A
P
Site 33
S357
E
A
P
G
T
K
R
S
P
S
A
P
A
A
T
Site 34
S359
P
G
T
K
R
S
P
S
A
P
A
A
T
S
S
Site 35
T364
S
P
S
A
P
A
A
T
S
S
A
S
S
S
T
Site 36
S365
P
S
A
P
A
A
T
S
S
A
S
S
S
T
S
Site 37
S366
S
A
P
A
A
T
S
S
A
S
S
S
T
S
S
Site 38
S368
P
A
A
T
S
S
A
S
S
S
T
S
S
Y
K
Site 39
S369
A
A
T
S
S
A
S
S
S
T
S
S
Y
K
R
Site 40
S370
A
T
S
S
A
S
S
S
T
S
S
Y
K
R
A
Site 41
S372
S
S
A
S
S
S
T
S
S
Y
K
R
A
P
A
Site 42
S373
S
A
S
S
S
T
S
S
Y
K
R
A
P
A
S
Site 43
Y374
A
S
S
S
T
S
S
Y
K
R
A
P
A
S
S
Site 44
S380
S
Y
K
R
A
P
A
S
S
A
P
Q
P
K
P
Site 45
S381
Y
K
R
A
P
A
S
S
A
P
Q
P
K
P
L
Site 46
S456
G
L
P
A
L
E
A
S
Q
R
F
R
S
I
S
Site 47
S461
E
A
S
Q
R
F
R
S
I
S
T
L
E
L
F
Site 48
S463
S
Q
R
F
R
S
I
S
T
L
E
L
F
T
V
Site 49
S492
S
S
W
V
S
L
E
S
L
T
L
S
Y
N
G
Site 50
S496
S
L
E
S
L
T
L
S
Y
N
G
L
G
S
N
Site 51
S561
S
I
R
V
D
H
P
S
Q
R
D
N
P
G
V
Site 52
S576
P
G
N
A
G
P
P
S
H
I
I
G
D
E
E
Site 53
S615
S
V
L
K
A
S
G
S
L
Q
Q
L
S
L
D
Site 54
S620
S
G
S
L
Q
Q
L
S
L
D
S
A
T
F
A
Site 55
S623
L
Q
Q
L
S
L
D
S
A
T
F
A
S
P
Q
Site 56
T625
Q
L
S
L
D
S
A
T
F
A
S
P
Q
D
F
Site 57
S650
N
L
A
L
K
R
L
S
F
H
D
M
N
L
A
Site 58
S730
A
D
V
F
S
E
D
S
S
S
S
L
C
Q
L
Site 59
S731
D
V
F
S
E
D
S
S
S
S
L
C
Q
L
D
Site 60
S732
V
F
S
E
D
S
S
S
S
L
C
Q
L
D
I
Site 61
S733
F
S
E
D
S
S
S
S
L
C
Q
L
D
I
S
Site 62
S740
S
L
C
Q
L
D
I
S
S
N
C
I
K
P
D
Site 63
S741
L
C
Q
L
D
I
S
S
N
C
I
K
P
D
G
Site 64
T780
W
L
D
Q
D
A
V
T
A
R
E
A
I
R
R
Site 65
T791
A
I
R
R
L
R
A
T
C
H
V
V
S
D
S
Site 66
S796
R
A
T
C
H
V
V
S
D
S
W
D
S
S
Q
Site 67
S798
T
C
H
V
V
S
D
S
W
D
S
S
Q
A
F
Site 68
S802
V
S
D
S
W
D
S
S
Q
A
F
A
D
Y
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation