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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PCBP2
Full Name:
Poly(rC)-binding protein 2
Alias:
Alpha-CP2; Heterogenous nuclear ribonucleoprotein E2; HnRNP-E2; HNRPE2; PCB2; Poly (rC) binding protein 2
Type:
RNA binding protein
Mass (Da):
38580
Number AA:
365
UniProt ID:
Q15366
International Prot ID:
IPI00216689
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
GO:0030529
Uniprot
OncoNet
Molecular Function:
GO:0003677
GO:0003723
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0000398
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T15
G
G
L
N
V
T
L
T
I
R
L
L
M
H
G
Site 2
S35
I
I
G
K
K
G
E
S
V
K
K
M
R
E
E
Site 3
S43
V
K
K
M
R
E
E
S
G
A
R
I
N
I
S
Site 4
S50
S
G
A
R
I
N
I
S
E
G
N
C
P
E
R
Site 5
T60
N
C
P
E
R
I
I
T
L
A
G
P
T
N
A
Site 6
S84
D
K
L
E
E
D
I
S
S
S
M
T
N
S
T
Site 7
S85
K
L
E
E
D
I
S
S
S
M
T
N
S
T
A
Site 8
S86
L
E
E
D
I
S
S
S
M
T
N
S
T
A
A
Site 9
T88
E
D
I
S
S
S
M
T
N
S
T
A
A
S
R
Site 10
S90
I
S
S
S
M
T
N
S
T
A
A
S
R
P
P
Site 11
T91
S
S
S
M
T
N
S
T
A
A
S
R
P
P
V
Site 12
S94
M
T
N
S
T
A
A
S
R
P
P
V
T
L
R
Site 13
S126
K
I
K
E
I
R
E
S
T
G
A
Q
V
Q
V
Site 14
T127
I
K
E
I
R
E
S
T
G
A
Q
V
Q
V
A
Site 15
S141
A
G
D
M
L
P
N
S
T
E
R
A
I
T
I
Site 16
T142
G
D
M
L
P
N
S
T
E
R
A
I
T
I
A
Site 17
T147
N
S
T
E
R
A
I
T
I
A
G
I
P
Q
S
Site 18
S173
M
L
E
T
L
S
Q
S
P
P
K
G
V
T
I
Site 19
T179
Q
S
P
P
K
G
V
T
I
P
Y
R
P
K
P
Site 20
Y182
P
K
G
V
T
I
P
Y
R
P
K
P
S
S
S
Site 21
S187
I
P
Y
R
P
K
P
S
S
S
P
V
I
F
A
Site 22
S188
P
Y
R
P
K
P
S
S
S
P
V
I
F
A
G
Site 23
S189
Y
R
P
K
P
S
S
S
P
V
I
F
A
G
G
Site 24
Y200
F
A
G
G
Q
D
R
Y
S
T
G
S
D
S
A
Site 25
S201
A
G
G
Q
D
R
Y
S
T
G
S
D
S
A
S
Site 26
T202
G
G
Q
D
R
Y
S
T
G
S
D
S
A
S
F
Site 27
S204
Q
D
R
Y
S
T
G
S
D
S
A
S
F
P
H
Site 28
S206
R
Y
S
T
G
S
D
S
A
S
F
P
H
T
T
Site 29
S208
S
T
G
S
D
S
A
S
F
P
H
T
T
P
S
Site 30
T212
D
S
A
S
F
P
H
T
T
P
S
M
C
L
N
Site 31
T213
S
A
S
F
P
H
T
T
P
S
M
C
L
N
P
Site 32
S215
S
F
P
H
T
T
P
S
M
C
L
N
P
D
L
Site 33
Y230
E
G
P
P
L
E
A
Y
T
I
Q
G
Q
Y
A
Site 34
T231
G
P
P
L
E
A
Y
T
I
Q
G
Q
Y
A
I
Site 35
Y236
A
Y
T
I
Q
G
Q
Y
A
I
P
Q
P
D
L
Site 36
T244
A
I
P
Q
P
D
L
T
K
L
H
Q
L
A
M
Site 37
S254
H
Q
L
A
M
Q
Q
S
H
F
P
M
T
H
G
Site 38
T259
Q
Q
S
H
F
P
M
T
H
G
N
T
G
F
S
Site 39
T263
F
P
M
T
H
G
N
T
G
F
S
G
I
E
S
Site 40
S266
T
H
G
N
T
G
F
S
G
I
E
S
S
S
P
Site 41
S270
T
G
F
S
G
I
E
S
S
S
P
E
V
K
G
Site 42
S271
G
F
S
G
I
E
S
S
S
P
E
V
K
G
Y
Site 43
S272
F
S
G
I
E
S
S
S
P
E
V
K
G
Y
W
Site 44
Y278
S
S
P
E
V
K
G
Y
W
G
L
D
A
S
A
Site 45
S284
G
Y
W
G
L
D
A
S
A
Q
T
T
S
H
E
Site 46
S289
D
A
S
A
Q
T
T
S
H
E
L
T
I
P
N
Site 47
T293
Q
T
T
S
H
E
L
T
I
P
N
D
L
I
G
Site 48
S317
I
N
E
I
R
Q
M
S
G
A
Q
I
K
I
A
Site 49
T336
G
S
T
D
R
Q
V
T
I
T
G
S
A
A
S
Site 50
T338
T
D
R
Q
V
T
I
T
G
S
A
A
S
I
S
Site 51
S356
Y
L
I
N
V
R
L
S
S
E
T
G
G
M
G
Site 52
S357
L
I
N
V
R
L
S
S
E
T
G
G
M
G
S
Site 53
T359
N
V
R
L
S
S
E
T
G
G
M
G
S
S
_
Site 54
S364
S
E
T
G
G
M
G
S
S
_
_
_
_
_
_
Site 55
S365
E
T
G
G
M
G
S
S
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation