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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MTFR1
Full Name:
Mitochondrial fission regulator 1
Alias:
Chondrocyte protein with a poly-proline region; CHPPR;
Type:
Mitochondrial
Mass (Da):
37000
Number AA:
333
UniProt ID:
Q15390
International Prot ID:
IPI00016699
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005739
GO:0005886
GO:0016020
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S22
Q
V
G
V
S
M
Q
S
V
L
W
S
R
K
P
Site 2
S26
S
M
Q
S
V
L
W
S
R
K
P
Y
G
S
S
Site 3
Y30
V
L
W
S
R
K
P
Y
G
S
S
R
S
I
V
Site 4
S32
W
S
R
K
P
Y
G
S
S
R
S
I
V
R
K
Site 5
S35
K
P
Y
G
S
S
R
S
I
V
R
K
I
G
T
Site 6
S45
R
K
I
G
T
N
L
S
L
I
Q
C
P
R
V
Site 7
S64
N
S
H
A
T
E
W
S
P
S
H
P
G
E
D
Site 8
S66
H
A
T
E
W
S
P
S
H
P
G
E
D
A
V
Site 9
S90
A
K
E
E
G
E
C
S
A
R
L
R
T
E
V
Site 10
T95
E
C
S
A
R
L
R
T
E
V
R
S
R
P
P
Site 11
S99
R
L
R
T
E
V
R
S
R
P
P
L
Q
D
D
Site 12
S115
L
F
F
E
K
A
P
S
R
Q
I
S
L
P
D
Site 13
S119
K
A
P
S
R
Q
I
S
L
P
D
L
S
Q
E
Site 14
S124
Q
I
S
L
P
D
L
S
Q
E
E
P
Q
L
K
Site 15
T132
Q
E
E
P
Q
L
K
T
P
A
L
A
N
E
E
Site 16
T178
T
A
G
D
L
D
S
T
T
F
G
T
I
P
P
Site 17
T179
A
G
D
L
D
S
T
T
F
G
T
I
P
P
H
Site 18
T182
L
D
S
T
T
F
G
T
I
P
P
H
P
P
P
Site 19
S206
L
G
L
H
Q
S
T
S
A
V
D
L
I
K
E
Site 20
T224
K
R
A
N
A
G
K
T
L
V
K
N
N
P
K
Site 21
S247
E
I
L
K
E
M
N
S
V
K
L
R
S
V
K
Site 22
S252
M
N
S
V
K
L
R
S
V
K
R
S
E
Q
D
Site 23
S256
K
L
R
S
V
K
R
S
E
Q
D
V
K
P
K
Site 24
Y284
A
L
K
K
K
F
A
Y
R
Y
R
S
D
S
Q
Site 25
Y286
K
K
K
F
A
Y
R
Y
R
S
D
S
Q
D
E
Site 26
S288
K
F
A
Y
R
Y
R
S
D
S
Q
D
E
V
E
Site 27
S290
A
Y
R
Y
R
S
D
S
Q
D
E
V
E
K
G
Site 28
S301
V
E
K
G
I
P
K
S
E
S
E
A
T
S
E
Site 29
S303
K
G
I
P
K
S
E
S
E
A
T
S
E
R
V
Site 30
T306
P
K
S
E
S
E
A
T
S
E
R
V
L
F
G
Site 31
S307
K
S
E
S
E
A
T
S
E
R
V
L
F
G
P
Site 32
T320
G
P
H
M
L
K
P
T
G
K
M
K
A
L
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation