KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
CNN3
Full Name:
Calponin-3
Alias:
Calponin 3, acidic; Calponin, acidic isoform; CLP3
Type:
Cytoskeletal protein
Mass (Da):
36414
Number AA:
329
UniProt ID:
Q15417
International Prot ID:
IPI00216682
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0003779
GO:0005516
GO:0005523
PhosphoSite+
KinaseNET
Biological Process:
GO:0031032
GO:0006939
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T2
_
_
_
_
_
_
M
T
H
F
N
K
G
P
S
Site 2
Y10
H
F
N
K
G
P
S
Y
G
L
S
A
E
V
K
Site 3
S13
K
G
P
S
Y
G
L
S
A
E
V
K
N
K
I
Site 4
Y24
K
N
K
I
A
S
K
Y
D
H
Q
A
E
E
D
Site 5
T40
R
N
W
I
E
E
V
T
G
M
S
I
G
P
N
Site 6
S43
I
E
E
V
T
G
M
S
I
G
P
N
F
Q
L
Site 7
S69
I
N
K
L
Q
P
G
S
V
K
K
V
N
E
S
Site 8
S77
V
K
K
V
N
E
S
S
L
N
W
P
Q
L
E
Site 9
T137
K
T
K
G
F
H
T
T
I
D
I
G
V
K
Y
Site 10
Y144
T
I
D
I
G
V
K
Y
A
E
K
Q
T
R
R
Site 11
S162
G
K
L
K
A
G
Q
S
V
I
G
L
Q
M
G
Site 12
T170
V
I
G
L
Q
M
G
T
N
K
C
A
S
Q
A
Site 13
S175
M
G
T
N
K
C
A
S
Q
A
G
M
T
A
Y
Site 14
Y182
S
Q
A
G
M
T
A
Y
G
T
R
R
H
L
Y
Site 15
T184
A
G
M
T
A
Y
G
T
R
R
H
L
Y
D
P
Site 16
Y189
Y
G
T
R
R
H
L
Y
D
P
K
M
Q
T
D
Site 17
T195
L
Y
D
P
K
M
Q
T
D
K
P
F
D
Q
T
Site 18
T203
D
K
P
F
D
Q
T
T
I
S
L
Q
M
G
T
Site 19
S205
P
F
D
Q
T
T
I
S
L
Q
M
G
T
N
K
Site 20
S215
M
G
T
N
K
G
A
S
Q
A
G
M
L
A
P
Site 21
T224
A
G
M
L
A
P
G
T
R
R
D
I
Y
D
Q
Site 22
Y229
P
G
T
R
R
D
I
Y
D
Q
K
L
T
L
Q
Site 23
T234
D
I
Y
D
Q
K
L
T
L
Q
P
V
D
N
S
Site 24
S241
T
L
Q
P
V
D
N
S
T
I
S
L
Q
M
G
Site 25
T242
L
Q
P
V
D
N
S
T
I
S
L
Q
M
G
T
Site 26
S244
P
V
D
N
S
T
I
S
L
Q
M
G
T
N
K
Site 27
S254
M
G
T
N
K
V
A
S
Q
K
G
M
S
V
Y
Site 28
S259
V
A
S
Q
K
G
M
S
V
Y
G
L
G
R
Q
Site 29
Y261
S
Q
K
G
M
S
V
Y
G
L
G
R
Q
V
Y
Site 30
Y268
Y
G
L
G
R
Q
V
Y
D
P
K
Y
C
A
A
Site 31
Y272
R
Q
V
Y
D
P
K
Y
C
A
A
P
T
E
P
Site 32
S285
E
P
V
I
H
N
G
S
Q
G
T
G
T
N
G
Site 33
T290
N
G
S
Q
G
T
G
T
N
G
S
E
I
S
D
Site 34
S293
Q
G
T
G
T
N
G
S
E
I
S
D
S
D
Y
Site 35
S296
G
T
N
G
S
E
I
S
D
S
D
Y
Q
A
E
Site 36
S298
N
G
S
E
I
S
D
S
D
Y
Q
A
E
Y
P
Site 37
Y300
S
E
I
S
D
S
D
Y
Q
A
E
Y
P
D
E
Site 38
Y304
D
S
D
Y
Q
A
E
Y
P
D
E
Y
H
G
E
Site 39
Y308
Q
A
E
Y
P
D
E
Y
H
G
E
Y
Q
D
D
Site 40
Y312
P
D
E
Y
H
G
E
Y
Q
D
D
Y
P
R
D
Site 41
Y316
H
G
E
Y
Q
D
D
Y
P
R
D
Y
Q
Y
S
Site 42
Y320
Q
D
D
Y
P
R
D
Y
Q
Y
S
D
Q
G
I
Site 43
Y322
D
Y
P
R
D
Y
Q
Y
S
D
Q
G
I
D
Y
Site 44
S323
Y
P
R
D
Y
Q
Y
S
D
Q
G
I
D
Y
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation