PhosphoNET

           
Protein Info 
   
Short Name:  SF3B4
Full Name:  Splicing factor 3B subunit 4
Alias:  Pre-mRNA splicing factor SF3b 49 kDa subunit; SAP 49; SAP49; SF3b49; SF3b50; Spliceosome associated protein 49; Spliceosome-associated protein 49; Splicing factor 3b, subunit 4, 49kDa
Type:  RNA binding protein
Mass (Da):  44386
Number AA:  424
UniProt ID:  Q15427
International Prot ID:  IPI00017339
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005634  GO:0005681  GO:0030529 Uniprot OncoNet
Molecular Function:  GO:0000166  GO:0003676  GO:0003723 PhosphoSite+ KinaseNET
Biological Process:  GO:0000375  GO:0000377  GO:0000398 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S7_MAAGPISERNQDAT
Site 2T14SERNQDATVYVGGLD
Site 3Y16RNQDATVYVGGLDEK
Site 4S25GGLDEKVSEPLLWEL
Site 5T50HMPKDRVTGQHQGYG
Site 6Y56VTGQHQGYGFVEFLS
Site 7S63YGFVEFLSEEDADYA
Site 8Y69LSEEDADYAIKIMNM
Site 9S90PIRVNKASAHNKNLD
Site 10Y117EIDEKLLYDTFSAFG
Site 11T138KIMRDPDTGNSKGYA
Site 12S141RDPDTGNSKGYAFIN
Site 13Y166IEAMNGQYLCNRPIT
Site 14T173YLCNRPITVSYAFKK
Site 15S175CNRPITVSYAFKKDS
Site 16S189SKGERHGSAAERLLA
Site 17S202LAAQNPLSQADRPHQ
Site 18S219ADAPPPPSAPNPVVS
Site 19S242PGMPPPGSFPPPVPP
Site 20S277AAGHGPPSAGTPGAG
Site 21T280HGPPSAGTPGAGHPG
Site 22S291GHPGHGHSHPHPFPP
Site 23S329PHAGPPGSGGQPPPR
Site 24S360PRGPPFGSPMGHPGP
Site 25Y385PLMPPHGYTGPPRPP
Site 26T386LMPPHGYTGPPRPPP
Site 27Y394GPPRPPPYGYQRGPL
Site 28Y396PRPPPYGYQRGPLPP
Site 29T407PLPPPRPTPRPPVPP
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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