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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SYCP1
Full Name:
Synaptonemal complex protein 1
Alias:
Cancer/testis antigen 8; CT8; HOM-TES-14; SCP1
Type:
DNA binding protein
Mass (Da):
114192
Number AA:
976
UniProt ID:
Q15431
International Prot ID:
IPI00216137
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0003677
PhosphoSite+
KinaseNET
Biological Process:
GO:0051301
GO:0007131
GO:0007283
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S15
A
L
F
V
P
P
R
S
S
S
S
Q
V
S
A
Site 2
S17
F
V
P
P
R
S
S
S
S
Q
V
S
A
V
K
Site 3
S18
V
P
P
R
S
S
S
S
Q
V
S
A
V
K
P
Site 4
S21
R
S
S
S
S
Q
V
S
A
V
K
P
Q
T
L
Site 5
T27
V
S
A
V
K
P
Q
T
L
G
G
D
S
T
F
Site 6
T33
Q
T
L
G
G
D
S
T
F
F
K
S
F
N
K
Site 7
S37
G
D
S
T
F
F
K
S
F
N
K
C
T
E
D
Site 8
S56
P
F
A
K
T
N
L
S
K
N
G
E
N
I
D
Site 9
S64
K
N
G
E
N
I
D
S
D
P
A
L
Q
K
V
Site 10
Y87
V
G
N
S
D
C
H
Y
Q
E
G
L
K
D
S
Site 11
S94
Y
Q
E
G
L
K
D
S
D
L
E
N
S
E
G
Site 12
S99
K
D
S
D
L
E
N
S
E
G
L
S
R
V
Y
Site 13
S103
L
E
N
S
E
G
L
S
R
V
Y
S
K
L
Y
Site 14
Y106
S
E
G
L
S
R
V
Y
S
K
L
Y
K
E
A
Site 15
S107
E
G
L
S
R
V
Y
S
K
L
Y
K
E
A
E
Site 16
Y110
S
R
V
Y
S
K
L
Y
K
E
A
E
K
I
K
Site 17
T179
L
I
K
E
N
N
A
T
R
H
L
C
N
L
L
Site 18
T189
L
C
N
L
L
K
E
T
C
A
R
S
A
E
K
Site 19
T197
C
A
R
S
A
E
K
T
K
K
Y
E
Y
E
R
Site 20
Y200
S
A
E
K
T
K
K
Y
E
Y
E
R
E
E
T
Site 21
Y202
E
K
T
K
K
Y
E
Y
E
R
E
E
T
R
Q
Site 22
T207
Y
E
Y
E
R
E
E
T
R
Q
V
Y
M
D
L
Site 23
Y211
R
E
E
T
R
Q
V
Y
M
D
L
N
N
N
I
Site 24
T223
N
N
I
E
K
M
I
T
A
F
E
E
L
R
V
Site 25
Y247
H
F
K
L
K
E
D
Y
E
K
I
Q
H
L
E
Site 26
Y257
I
Q
H
L
E
Q
E
Y
K
K
E
I
N
D
K
Site 27
S269
N
D
K
E
K
Q
V
S
L
L
L
I
Q
I
T
Site 28
T286
E
N
K
M
K
D
L
T
F
L
L
E
E
S
R
Site 29
S313
Q
S
E
N
L
K
Q
S
I
E
K
Q
H
H
L
Site 30
S330
E
L
E
D
I
K
V
S
L
Q
R
S
V
S
T
Site 31
S334
I
K
V
S
L
Q
R
S
V
S
T
Q
K
A
L
Site 32
S336
V
S
L
Q
R
S
V
S
T
Q
K
A
L
E
E
Site 33
T351
D
L
Q
I
A
T
K
T
I
C
Q
L
T
E
E
Site 34
T361
Q
L
T
E
E
K
E
T
Q
M
E
E
S
N
K
Site 35
S374
N
K
A
R
A
A
H
S
F
V
V
T
E
F
E
Site 36
S386
E
F
E
T
T
V
C
S
L
E
E
L
L
R
T
Site 37
T393
S
L
E
E
L
L
R
T
E
Q
Q
R
L
E
K
Site 38
S417
M
E
L
Q
K
K
S
S
E
L
E
E
M
T
K
Site 39
Y448
G
E
K
E
T
L
L
Y
E
N
K
Q
F
E
K
Site 40
T463
I
A
E
E
L
K
G
T
E
Q
E
L
I
G
L
Site 41
T486
H
D
L
E
I
Q
L
T
A
I
T
T
S
E
Q
Site 42
S496
T
T
S
E
Q
Y
Y
S
K
E
V
K
D
L
K
Site 43
T504
K
E
V
K
D
L
K
T
E
L
E
N
E
K
L
Site 44
S518
L
K
N
T
E
L
T
S
H
C
N
K
L
S
L
Site 45
S524
T
S
H
C
N
K
L
S
L
E
N
K
E
L
T
Site 46
T531
S
L
E
N
K
E
L
T
Q
E
T
S
D
M
T
Site 47
S535
K
E
L
T
Q
E
T
S
D
M
T
L
E
L
K
Site 48
T538
T
Q
E
T
S
D
M
T
L
E
L
K
N
Q
Q
Site 49
Y578
Q
L
R
N
E
L
E
Y
V
R
E
E
L
K
Q
Site 50
S597
V
K
C
K
L
D
K
S
E
E
N
C
N
N
L
Site 51
Y639
E
S
K
Q
L
N
V
Y
E
I
K
V
N
K
L
Site 52
T663
K
F
G
E
I
T
D
T
Y
Q
K
E
I
E
D
Site 53
Y664
F
G
E
I
T
D
T
Y
Q
K
E
I
E
D
K
Site 54
S674
E
I
E
D
K
K
I
S
E
E
N
L
L
E
E
Site 55
S730
K
I
I
E
E
R
D
S
E
L
G
L
Y
K
S
Site 56
Y735
R
D
S
E
L
G
L
Y
K
S
K
E
Q
E
Q
Site 57
S737
S
E
L
G
L
Y
K
S
K
E
Q
E
Q
S
S
Site 58
S743
K
S
K
E
Q
E
Q
S
S
L
R
A
S
L
E
Site 59
S744
S
K
E
Q
E
Q
S
S
L
R
A
S
L
E
I
Site 60
S748
E
Q
S
S
L
R
A
S
L
E
I
E
L
S
N
Site 61
T785
K
R
E
A
K
E
N
T
A
T
L
K
E
K
K
Site 62
T787
E
A
K
E
N
T
A
T
L
K
E
K
K
D
K
Site 63
T796
K
E
K
K
D
K
K
T
Q
T
F
L
L
E
T
Site 64
T798
K
K
D
K
K
T
Q
T
F
L
L
E
T
P
E
Site 65
T803
T
Q
T
F
L
L
E
T
P
E
I
Y
W
K
L
Site 66
Y807
L
L
E
T
P
E
I
Y
W
K
L
D
S
K
A
Site 67
S812
E
I
Y
W
K
L
D
S
K
A
V
P
S
Q
T
Site 68
S817
L
D
S
K
A
V
P
S
Q
T
V
S
R
N
F
Site 69
T819
S
K
A
V
P
S
Q
T
V
S
R
N
F
T
S
Site 70
S821
A
V
P
S
Q
T
V
S
R
N
F
T
S
V
D
Site 71
T825
Q
T
V
S
R
N
F
T
S
V
D
H
G
I
S
Site 72
Y838
I
S
K
D
K
R
D
Y
L
W
T
S
A
K
N
Site 73
T841
D
K
R
D
Y
L
W
T
S
A
K
N
T
L
S
Site 74
S842
K
R
D
Y
L
W
T
S
A
K
N
T
L
S
T
Site 75
T846
L
W
T
S
A
K
N
T
L
S
T
P
L
P
K
Site 76
S848
T
S
A
K
N
T
L
S
T
P
L
P
K
A
Y
Site 77
T849
S
A
K
N
T
L
S
T
P
L
P
K
A
Y
T
Site 78
Y855
S
T
P
L
P
K
A
Y
T
V
K
T
P
T
K
Site 79
T859
P
K
A
Y
T
V
K
T
P
T
K
P
K
L
Q
Site 80
S892
A
F
E
F
D
I
N
S
D
S
S
E
T
T
D
Site 81
S894
E
F
D
I
N
S
D
S
S
E
T
T
D
L
L
Site 82
T898
N
S
D
S
S
E
T
T
D
L
L
S
M
V
S
Site 83
S902
S
E
T
T
D
L
L
S
M
V
S
E
E
E
T
Site 84
S905
T
D
L
L
S
M
V
S
E
E
E
T
L
K
T
Site 85
T909
S
M
V
S
E
E
E
T
L
K
T
L
Y
R
N
Site 86
T912
S
E
E
E
T
L
K
T
L
Y
R
N
N
N
P
Site 87
Y914
E
E
T
L
K
T
L
Y
R
N
N
N
P
P
A
Site 88
S922
R
N
N
N
P
P
A
S
H
L
C
V
K
T
P
Site 89
T928
A
S
H
L
C
V
K
T
P
K
K
A
P
S
S
Site 90
S934
K
T
P
K
K
A
P
S
S
L
T
T
P
G
S
Site 91
S935
T
P
K
K
A
P
S
S
L
T
T
P
G
S
T
Site 92
T937
K
K
A
P
S
S
L
T
T
P
G
S
T
L
K
Site 93
T938
K
A
P
S
S
L
T
T
P
G
S
T
L
K
F
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation