KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
SEC23A
Full Name:
Protein transport protein Sec23A
Alias:
CLSD; Sec23 A
Type:
Mass (Da):
86160
Number AA:
UniProt ID:
Q15436
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030127
GO:0005829
GO:0005783
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006888
GO:0006886
GO:0016044
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S20
E
R
D
G
V
R
F
S
W
N
V
W
P
S
S
Site 2
S27
S
W
N
V
W
P
S
S
R
L
E
A
T
R
M
Site 3
T43
V
P
V
A
A
L
F
T
P
L
K
E
R
P
D
Site 4
Y56
P
D
L
P
P
I
Q
Y
E
P
V
L
C
S
R
Site 5
S62
Q
Y
E
P
V
L
C
S
R
T
T
C
R
A
V
Site 6
Y78
N
P
L
C
Q
V
D
Y
R
A
K
L
W
A
C
Site 7
S97
Q
R
N
Q
F
P
P
S
Y
A
G
I
S
E
L
Site 8
Y98
R
N
Q
F
P
P
S
Y
A
G
I
S
E
L
N
Site 9
S102
P
P
S
Y
A
G
I
S
E
L
N
Q
P
A
E
Site 10
Y119
P
Q
F
S
S
I
E
Y
V
V
L
R
G
P
Q
Site 11
S150
D
L
Q
A
L
K
E
S
M
Q
M
S
L
S
L
Site 12
S154
L
K
E
S
M
Q
M
S
L
S
L
L
P
P
T
Site 13
S186
G
C
E
G
I
S
K
S
Y
V
F
R
G
T
K
Site 14
Y187
C
E
G
I
S
K
S
Y
V
F
R
G
T
K
D
Site 15
T192
K
S
Y
V
F
R
G
T
K
D
L
S
A
K
Q
Site 16
T212
G
L
S
K
V
P
L
T
Q
A
T
R
G
P
Q
Site 17
S226
Q
V
Q
Q
P
P
P
S
N
R
F
L
Q
P
V
Site 18
S263
Q
G
K
R
P
L
R
S
S
G
V
A
L
S
I
Site 19
S264
G
K
R
P
L
R
S
S
G
V
A
L
S
I
A
Site 20
T308
V
V
G
D
E
L
K
T
P
I
R
S
W
H
D
Site 21
Y323
I
D
K
D
N
A
K
Y
V
K
K
G
T
K
H
Site 22
S376
G
Y
M
V
M
G
D
S
F
N
T
S
L
F
K
Site 23
S380
M
G
D
S
F
N
T
S
L
F
K
Q
T
F
Q
Site 24
T385
N
T
S
L
F
K
Q
T
F
Q
R
V
F
T
K
Site 25
T405
F
K
M
G
F
G
G
T
L
E
I
K
T
S
R
Site 26
T410
G
G
T
L
E
I
K
T
S
R
E
I
K
I
S
Site 27
S411
G
T
L
E
I
K
T
S
R
E
I
K
I
S
G
Site 28
S428
G
P
C
V
S
L
N
S
K
G
P
C
V
S
E
Site 29
S434
N
S
K
G
P
C
V
S
E
N
E
I
G
T
G
Site 30
T483
R
G
A
I
Q
F
V
T
Q
Y
Q
H
S
S
G
Site 31
Y485
A
I
Q
F
V
T
Q
Y
Q
H
S
S
G
Q
R
Site 32
S489
V
T
Q
Y
Q
H
S
S
G
Q
R
R
I
R
V
Site 33
T497
G
Q
R
R
I
R
V
T
T
I
A
R
N
W
A
Site 34
T498
Q
R
R
I
R
V
T
T
I
A
R
N
W
A
D
Site 35
S516
Q
I
Q
N
I
A
A
S
F
D
Q
E
A
A
A
Site 36
T536
L
A
I
Y
R
A
E
T
E
E
G
P
D
V
L
Site 37
Y560
L
C
Q
K
F
G
E
Y
H
K
D
D
P
S
S
Site 38
S566
E
Y
H
K
D
D
P
S
S
F
R
F
S
E
T
Site 39
S567
Y
H
K
D
D
P
S
S
F
R
F
S
E
T
F
Site 40
S571
D
P
S
S
F
R
F
S
E
T
F
S
L
Y
P
Site 41
T573
S
S
F
R
F
S
E
T
F
S
L
Y
P
Q
F
Site 42
S588
M
F
H
L
R
R
S
S
F
L
Q
V
F
N
N
Site 43
S596
F
L
Q
V
F
N
N
S
P
D
E
S
S
Y
Y
Site 44
Y602
N
S
P
D
E
S
S
Y
Y
R
H
H
F
M
R
Site 45
Y603
S
P
D
E
S
S
Y
Y
R
H
H
F
M
R
Q
Site 46
Y626
I
Q
P
I
L
Y
A
Y
S
F
S
G
P
P
E
Site 47
S627
Q
P
I
L
Y
A
Y
S
F
S
G
P
P
E
P
Site 48
S639
P
E
P
V
L
L
D
S
S
S
I
L
A
D
R
Site 49
Y678
G
Y
Q
D
M
P
E
Y
E
N
F
R
H
L
L
Site 50
S698
D
A
Q
E
I
L
H
S
R
F
P
M
P
R
Y
Site 51
Y705
S
R
F
P
M
P
R
Y
I
D
T
E
H
G
G
Site 52
T708
P
M
P
R
Y
I
D
T
E
H
G
G
S
Q
A
Site 53
S713
I
D
T
E
H
G
G
S
Q
A
R
F
L
L
S
Site 54
S720
S
Q
A
R
F
L
L
S
K
V
N
P
S
Q
T
Site 55
S725
L
L
S
K
V
N
P
S
Q
T
H
N
N
M
Y
Site 56
Y732
S
Q
T
H
N
N
M
Y
A
W
G
Q
E
S
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation