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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
RGN
Full Name:
Regucalcin
Alias:
RC; Regucalcin; Senescence marker protein 30; Senescence marker protein-30; SMP30; SMP-30
Type:
Mass (Da):
33253
Number AA:
299
UniProt ID:
Q15493
International Prot ID:
IPI00017551
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0030234
PhosphoSite+
KinaseNET
Biological Process:
GO:0006874
GO:0032781
GO:0050848
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S19
E
N
C
R
C
G
E
S
P
V
W
E
E
V
S
Site 2
S44
K
K
V
C
R
W
D
S
F
T
K
Q
V
Q
R
Site 3
T46
V
C
R
W
D
S
F
T
K
Q
V
Q
R
V
T
Site 4
T53
T
K
Q
V
Q
R
V
T
M
D
A
P
V
S
S
Site 5
S60
T
M
D
A
P
V
S
S
V
A
L
R
Q
S
G
Site 6
Y69
A
L
R
Q
S
G
G
Y
V
A
T
I
G
T
K
Site 7
Y113
K
V
D
P
A
G
R
Y
F
A
G
T
M
A
E
Site 8
T117
A
G
R
Y
F
A
G
T
M
A
E
E
T
A
P
Site 9
Y135
E
R
H
Q
G
A
L
Y
S
L
F
P
D
H
H
Site 10
S136
R
H
Q
G
A
L
Y
S
L
F
P
D
H
H
V
Site 11
Y146
P
D
H
H
V
K
K
Y
F
D
Q
V
D
I
S
Site 12
Y166
S
L
D
H
K
I
F
Y
Y
I
D
S
L
S
Y
Site 13
Y167
L
D
H
K
I
F
Y
Y
I
D
S
L
S
Y
S
Site 14
S172
F
Y
Y
I
D
S
L
S
Y
S
V
D
A
F
D
Site 15
S174
Y
I
D
S
L
S
Y
S
V
D
A
F
D
Y
D
Site 16
Y180
Y
S
V
D
A
F
D
Y
D
L
Q
T
G
Q
I
Site 17
T184
A
F
D
Y
D
L
Q
T
G
Q
I
S
N
R
R
Site 18
S188
D
L
Q
T
G
Q
I
S
N
R
R
S
V
Y
K
Site 19
S192
G
Q
I
S
N
R
R
S
V
Y
K
L
E
K
E
Site 20
Y194
I
S
N
R
R
S
V
Y
K
L
E
K
E
E
Q
Site 21
T237
V
T
G
K
R
L
Q
T
V
K
L
P
V
D
K
Site 22
T246
K
L
P
V
D
K
T
T
S
C
C
F
G
G
K
Site 23
Y259
G
K
N
Y
S
E
M
Y
V
T
C
A
R
D
G
Site 24
S296
V
K
G
I
A
P
Y
S
Y
A
G
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation