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Updated November 2019
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Protein Info
Short Name:
SURF2
Full Name:
Surfeit locus protein 2
Alias:
Surf-2; Surfeit 2
Type:
Unknown function
Mass (Da):
29618
Number AA:
256
UniProt ID:
Q15527
International Prot ID:
IPI00018037
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S17
A
F
L
R
E
H
P
S
L
R
L
Q
T
D
A
Site 2
T22
H
P
S
L
R
L
Q
T
D
A
R
K
V
R
C
Site 3
T32
R
K
V
R
C
I
L
T
G
H
E
L
P
C
R
Site 4
Y46
R
L
P
E
L
Q
V
Y
T
R
G
K
K
Y
Q
Site 5
Y52
V
Y
T
R
G
K
K
Y
Q
R
L
V
R
A
S
Site 6
S59
Y
Q
R
L
V
R
A
S
P
A
F
D
Y
A
E
Site 7
Y64
R
A
S
P
A
F
D
Y
A
E
F
E
P
H
I
Site 8
T75
E
P
H
I
V
P
S
T
K
N
P
H
Q
L
F
Site 9
T101
P
E
H
V
L
R
H
T
Q
G
R
R
Y
Q
R
Site 10
Y106
R
H
T
Q
G
R
R
Y
Q
R
A
L
C
K
Y
Site 11
Y113
Y
Q
R
A
L
C
K
Y
E
E
C
Q
K
Q
G
Site 12
T154
R
E
A
F
W
E
P
T
S
S
D
E
G
G
A
Site 13
S155
E
A
F
W
E
P
T
S
S
D
E
G
G
A
A
Site 14
S156
A
F
W
E
P
T
S
S
D
E
G
G
A
A
S
Site 15
S163
S
D
E
G
G
A
A
S
D
D
S
M
T
D
L
Site 16
S166
G
G
A
A
S
D
D
S
M
T
D
L
Y
P
P
Site 17
T168
A
A
S
D
D
S
M
T
D
L
Y
P
P
E
L
Site 18
Y171
D
D
S
M
T
D
L
Y
P
P
E
L
F
T
R
Site 19
S183
F
T
R
K
D
L
G
S
T
E
D
G
D
G
T
Site 20
T184
T
R
K
D
L
G
S
T
E
D
G
D
G
T
D
Site 21
T190
S
T
E
D
G
D
G
T
D
D
F
L
T
D
K
Site 22
T195
D
G
T
D
D
F
L
T
D
K
E
D
E
K
A
Site 23
T217
T
D
E
G
R
R
E
T
T
V
Y
R
G
L
V
Site 24
T218
D
E
G
R
R
E
T
T
V
Y
R
G
L
V
Q
Site 25
Y220
G
R
R
E
T
T
V
Y
R
G
L
V
Q
K
R
Site 26
S234
R
G
K
K
Q
L
G
S
L
K
K
K
F
K
S
Site 27
S241
S
L
K
K
K
F
K
S
H
H
R
K
P
K
S
Site 28
S248
S
H
H
R
K
P
K
S
F
S
S
C
K
Q
P
Site 29
S250
H
R
K
P
K
S
F
S
S
C
K
Q
P
G
_
Site 30
S251
R
K
P
K
S
F
S
S
C
K
Q
P
G
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation