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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MAPRE2
Full Name:
Microtubule-associated protein RP/EB family member 2
Alias:
APC-binding protein EB1; APC-binding protein EB2; EB1; End-binding protein 2; MARE2; Microtubule-associated protein, RP/EB family, member 2; RP1; T-cell activation protein
Type:
Cytoskeletal protein
Mass (Da):
37031
Number AA:
327
UniProt ID:
Q15555
International Prot ID:
IPI00003420
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005874
Uniprot
OncoNet
Molecular Function:
GO:0008017
PhosphoSite+
KinaseNET
Biological Process:
GO:0051301
GO:0008283
GO:0007067
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T5
_
_
_
M
P
G
P
T
Q
T
L
S
P
N
G
Site 2
T7
_
M
P
G
P
T
Q
T
L
S
P
N
G
E
N
Site 3
S9
P
G
P
T
Q
T
L
S
P
N
G
E
N
N
N
Site 4
T25
I
I
Q
D
N
N
G
T
I
I
P
F
R
K
H
Site 5
T33
I
I
P
F
R
K
H
T
V
R
G
E
R
S
Y
Site 6
Y40
T
V
R
G
E
R
S
Y
S
W
G
M
A
V
N
Site 7
S41
V
R
G
E
R
S
Y
S
W
G
M
A
V
N
V
Site 8
T54
N
V
Y
S
T
S
I
T
Q
E
T
M
S
R
H
Site 9
T57
S
T
S
I
T
Q
E
T
M
S
R
H
D
I
I
Site 10
T76
D
I
V
S
L
N
Y
T
K
V
E
Q
L
C
S
Site 11
Y114
Q
A
K
L
E
H
E
Y
I
H
N
F
K
L
L
Site 12
S124
N
F
K
L
L
Q
A
S
F
K
R
M
N
V
D
Site 13
Y158
I
Q
W
F
K
K
F
Y
D
A
N
Y
D
G
K
Site 14
Y162
K
K
F
Y
D
A
N
Y
D
G
K
E
Y
D
P
Site 15
Y167
A
N
Y
D
G
K
E
Y
D
P
V
E
A
R
Q
Site 16
S195
I
F
N
L
P
K
K
S
H
H
A
N
S
P
T
Site 17
S200
K
K
S
H
H
A
N
S
P
T
A
G
A
A
K
Site 18
S208
P
T
A
G
A
A
K
S
S
P
A
A
K
P
G
Site 19
S209
T
A
G
A
A
K
S
S
P
A
A
K
P
G
S
Site 20
S216
S
P
A
A
K
P
G
S
T
P
S
R
P
S
S
Site 21
T217
P
A
A
K
P
G
S
T
P
S
R
P
S
S
A
Site 22
S219
A
K
P
G
S
T
P
S
R
P
S
S
A
K
R
Site 23
S222
G
S
T
P
S
R
P
S
S
A
K
R
A
S
S
Site 24
S223
S
T
P
S
R
P
S
S
A
K
R
A
S
S
S
Site 25
S228
P
S
S
A
K
R
A
S
S
S
G
S
A
S
K
Site 26
S229
S
S
A
K
R
A
S
S
S
G
S
A
S
K
S
Site 27
S230
S
A
K
R
A
S
S
S
G
S
A
S
K
S
D
Site 28
S232
K
R
A
S
S
S
G
S
A
S
K
S
D
K
D
Site 29
S234
A
S
S
S
G
S
A
S
K
S
D
K
D
L
E
Site 30
S236
S
S
G
S
A
S
K
S
D
K
D
L
E
T
Q
Site 31
T242
K
S
D
K
D
L
E
T
Q
V
I
Q
L
N
E
Site 32
S253
Q
L
N
E
Q
V
H
S
L
K
L
A
L
E
G
Site 33
Y268
V
E
K
E
R
D
F
Y
F
G
K
L
R
E
I
Site 34
Y298
Q
R
L
M
D
I
L
Y
A
S
E
E
H
E
G
Site 35
S300
L
M
D
I
L
Y
A
S
E
E
H
E
G
H
T
Site 36
Y327
Q
P
P
Q
Q
E
E
Y
_
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation