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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TEAD4
Full Name:
Transcriptional enhancer factor TEF-3
Alias:
EFTR-2; RTEF1; RTEF-1; TCF13L1; TEA domain family member 4; TEAD-4; TEF3; TEF-3; TEFR-1; Transcription factor RTEF-1
Type:
Transcription protein
Mass (Da):
48329
Number AA:
434
UniProt ID:
Q15561
International Prot ID:
IPI00216204
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0003702
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0007517
GO:0001501
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
G
T
A
G
T
I
T
S
N
E
W
S
S
P
T
Site 2
S14
T
I
T
S
N
E
W
S
S
P
T
S
P
E
G
Site 3
S15
I
T
S
N
E
W
S
S
P
T
S
P
E
G
S
Site 4
S18
N
E
W
S
S
P
T
S
P
E
G
S
T
A
S
Site 5
S22
S
P
T
S
P
E
G
S
T
A
S
G
G
S
Q
Site 6
S25
S
P
E
G
S
T
A
S
G
G
S
Q
A
L
D
Site 7
S44
N
D
A
E
G
V
W
S
P
D
I
E
Q
S
F
Site 8
S50
W
S
P
D
I
E
Q
S
F
Q
E
A
L
A
I
Site 9
Y58
F
Q
E
A
L
A
I
Y
P
P
C
G
R
R
K
Site 10
S69
G
R
R
K
I
I
L
S
D
E
G
K
M
Y
G
Site 11
Y75
L
S
D
E
G
K
M
Y
G
R
N
E
L
I
A
Site 12
Y84
R
N
E
L
I
A
R
Y
I
K
L
R
T
G
K
Site 13
T92
I
K
L
R
T
G
K
T
R
T
R
K
Q
V
S
Site 14
S100
R
T
R
K
Q
V
S
S
H
I
Q
V
L
A
R
Site 15
S129
A
K
D
K
A
L
Q
S
M
A
A
M
S
S
A
Site 16
S160
G
P
G
R
P
A
V
S
G
F
W
Q
G
A
L
Site 17
S181
S
H
D
V
K
P
F
S
Q
Q
T
Y
A
V
Q
Site 18
Y185
K
P
F
S
Q
Q
T
Y
A
V
Q
P
P
L
P
Site 19
S198
L
P
L
P
G
F
E
S
P
A
G
P
A
P
S
Site 20
S205
S
P
A
G
P
A
P
S
P
S
A
P
P
A
P
Site 21
S207
A
G
P
A
P
S
P
S
A
P
P
A
P
P
W
Site 22
S218
A
P
P
W
Q
G
R
S
V
A
S
S
K
L
W
Site 23
S222
Q
G
R
S
V
A
S
S
K
L
W
M
L
E
F
Site 24
T241
E
Q
Q
Q
D
P
D
T
Y
N
K
H
L
F
V
Site 25
Y242
Q
Q
Q
D
P
D
T
Y
N
K
H
L
F
V
H
Site 26
S253
L
F
V
H
I
G
Q
S
S
P
S
Y
S
D
P
Site 27
S254
F
V
H
I
G
Q
S
S
P
S
Y
S
D
P
Y
Site 28
S256
H
I
G
Q
S
S
P
S
Y
S
D
P
Y
L
E
Site 29
Y257
I
G
Q
S
S
P
S
Y
S
D
P
Y
L
E
A
Site 30
S258
G
Q
S
S
P
S
Y
S
D
P
Y
L
E
A
V
Site 31
Y261
S
P
S
Y
S
D
P
Y
L
E
A
V
D
I
R
Site 32
Y271
A
V
D
I
R
Q
I
Y
D
K
F
P
E
K
K
Site 33
S290
D
L
F
E
R
G
P
S
N
A
F
F
L
V
K
Site 34
S311
T
N
I
E
D
E
G
S
S
F
Y
G
V
S
S
Site 35
S312
N
I
E
D
E
G
S
S
F
Y
G
V
S
S
Q
Site 36
Y314
E
D
E
G
S
S
F
Y
G
V
S
S
Q
Y
E
Site 37
S317
G
S
S
F
Y
G
V
S
S
Q
Y
E
S
P
E
Site 38
S318
S
S
F
Y
G
V
S
S
Q
Y
E
S
P
E
N
Site 39
Y320
F
Y
G
V
S
S
Q
Y
E
S
P
E
N
M
I
Site 40
S322
G
V
S
S
Q
Y
E
S
P
E
N
M
I
I
T
Site 41
T347
Q
V
V
E
K
V
E
T
E
Y
A
R
Y
E
N
Site 42
Y349
V
E
K
V
E
T
E
Y
A
R
Y
E
N
G
H
Site 43
Y352
V
E
T
E
Y
A
R
Y
E
N
G
H
Y
S
Y
Site 44
Y357
A
R
Y
E
N
G
H
Y
S
Y
R
I
H
R
S
Site 45
Y384
L
K
H
L
P
E
K
Y
M
M
N
S
V
L
E
Site 46
T404
Q
V
V
T
N
R
D
T
Q
E
T
L
L
C
I
Site 47
T407
T
N
R
D
T
Q
E
T
L
L
C
I
A
Y
V
Site 48
S420
Y
V
F
E
V
S
A
S
E
H
G
A
Q
H
H
Site 49
Y429
H
G
A
Q
H
H
I
Y
R
L
V
K
E
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation