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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TEAD2
Full Name:
Transcriptional enhancer factor TEF-4
Alias:
TEA domain family member 2
Type:
Mass (Da):
49243
Number AA:
447
UniProt ID:
Q15562
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
G
A
A
L
D
D
G
S
G
W
T
G
S
E
E
Site 2
S19
D
G
S
G
W
T
G
S
E
E
G
S
E
E
G
Site 3
S23
W
T
G
S
E
E
G
S
E
E
G
T
G
G
S
Site 4
T27
E
E
G
S
E
E
G
T
G
G
S
E
G
A
G
Site 5
S46
P
D
A
E
G
V
W
S
P
D
I
E
Q
S
F
Site 6
S52
W
S
P
D
I
E
Q
S
F
Q
E
A
L
A
I
Site 7
Y60
F
Q
E
A
L
A
I
Y
P
P
C
G
R
R
K
Site 8
S71
G
R
R
K
I
I
L
S
D
E
G
K
M
Y
G
Site 9
Y77
L
S
D
E
G
K
M
Y
G
R
N
E
L
I
A
Site 10
Y86
R
N
E
L
I
A
R
Y
I
K
L
R
T
G
K
Site 11
T94
I
K
L
R
T
G
K
T
R
T
R
K
Q
V
S
Site 12
S102
R
T
R
K
Q
V
S
S
H
I
Q
V
L
A
R
Site 13
S112
Q
V
L
A
R
R
K
S
R
E
I
Q
S
K
L
Site 14
S124
S
K
L
K
D
Q
V
S
K
D
K
A
F
Q
T
Site 15
T131
S
K
D
K
A
F
Q
T
M
A
T
M
S
S
A
Site 16
S142
M
S
S
A
Q
L
I
S
A
P
S
L
Q
A
K
Site 17
S158
G
P
T
G
P
Q
A
S
E
L
F
Q
F
W
S
Site 18
S165
S
E
L
F
Q
F
W
S
G
G
S
G
P
P
W
Site 19
S181
V
P
D
V
K
P
F
S
Q
T
P
F
T
L
S
Site 20
T183
D
V
K
P
F
S
Q
T
P
F
T
L
S
L
T
Site 21
T186
P
F
S
Q
T
P
F
T
L
S
L
T
P
P
S
Site 22
S188
S
Q
T
P
F
T
L
S
L
T
P
P
S
T
D
Site 23
T190
T
P
F
T
L
S
L
T
P
P
S
T
D
L
P
Site 24
S193
T
L
S
L
T
P
P
S
T
D
L
P
G
Y
E
Site 25
T194
L
S
L
T
P
P
S
T
D
L
P
G
Y
E
P
Site 26
Y199
P
S
T
D
L
P
G
Y
E
P
P
Q
A
L
S
Site 27
S206
Y
E
P
P
Q
A
L
S
P
L
P
P
P
T
P
Site 28
T212
L
S
P
L
P
P
P
T
P
S
P
P
A
W
Q
Site 29
S214
P
L
P
P
P
T
P
S
P
P
A
W
Q
A
R
Site 30
S245
E
P
P
D
A
V
D
S
Y
Q
R
H
L
F
V
Site 31
Y246
P
P
D
A
V
D
S
Y
Q
R
H
L
F
V
H
Site 32
S260
H
I
S
Q
H
C
P
S
P
G
A
P
P
L
E
Site 33
S268
P
G
A
P
P
L
E
S
V
D
V
R
Q
I
Y
Site 34
Y275
S
V
D
V
R
Q
I
Y
D
K
F
P
E
K
K
Site 35
Y289
K
G
G
L
R
E
L
Y
D
R
G
P
P
H
A
Site 36
S311
A
D
L
N
W
G
P
S
G
E
E
A
G
A
G
Site 37
S320
E
E
A
G
A
G
G
S
I
S
S
G
G
F
Y
Site 38
Y327
S
I
S
S
G
G
F
Y
G
V
S
S
Q
Y
E
Site 39
S330
S
G
G
F
Y
G
V
S
S
Q
Y
E
S
L
E
Site 40
S331
G
G
F
Y
G
V
S
S
Q
Y
E
S
L
E
H
Site 41
Y333
F
Y
G
V
S
S
Q
Y
E
S
L
E
H
M
T
Site 42
S335
G
V
S
S
Q
Y
E
S
L
E
H
M
T
L
T
Site 43
T340
Y
E
S
L
E
H
M
T
L
T
C
S
S
K
V
Site 44
T342
S
L
E
H
M
T
L
T
C
S
S
K
V
C
S
Site 45
S349
T
C
S
S
K
V
C
S
F
G
K
Q
V
V
E
Site 46
T360
Q
V
V
E
K
V
E
T
E
R
A
Q
L
E
D
Site 47
Y372
L
E
D
G
R
F
V
Y
R
L
L
R
S
P
M
Site 48
Y382
L
R
S
P
M
C
E
Y
L
V
N
F
L
H
K
Site 49
T417
Q
V
V
T
N
R
D
T
Q
E
L
L
L
C
T
Site 50
S431
T
A
Y
V
F
E
V
S
T
S
E
R
G
A
Q
Site 51
S433
Y
V
F
E
V
S
T
S
E
R
G
A
Q
H
H
Site 52
Y442
R
G
A
Q
H
H
I
Y
R
L
V
R
D
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation