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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TGFBI
Full Name:
Transforming growth factor-beta-induced protein ig-h3
Alias:
Kerato-epithelin;RGD-containing collagen-associated protein
Type:
Mass (Da):
74681
Number AA:
683
UniProt ID:
Q15582
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S28
T
L
A
G
P
A
K
S
P
Y
Q
L
V
L
Q
Site 2
Y30
A
G
P
A
K
S
P
Y
Q
L
V
L
Q
H
S
Site 3
S37
Y
Q
L
V
L
Q
H
S
R
L
R
G
R
Q
H
Site 4
Y82
G
K
S
T
V
I
S
Y
E
C
C
P
G
Y
E
Site 5
Y88
S
Y
E
C
C
P
G
Y
E
K
V
P
G
E
K
Site 6
Y121
G
S
T
T
T
Q
L
Y
T
D
R
T
E
K
L
Site 7
T122
S
T
T
T
Q
L
Y
T
D
R
T
E
K
L
R
Site 8
T125
T
Q
L
Y
T
D
R
T
E
K
L
R
P
E
M
Site 9
S137
P
E
M
E
G
P
G
S
F
T
I
F
A
P
S
Site 10
S150
P
S
N
E
A
W
A
S
L
P
A
E
V
L
D
Site 11
Y173
E
L
L
N
A
L
R
Y
H
M
V
G
R
R
V
Site 12
T182
M
V
G
R
R
V
L
T
D
E
L
K
H
G
M
Site 13
T192
L
K
H
G
M
T
L
T
S
M
Y
Q
N
S
N
Site 14
Y205
S
N
I
Q
I
H
H
Y
P
N
G
I
V
T
V
Site 15
T252
Q
I
I
E
I
E
D
T
F
E
T
L
R
A
A
Site 16
T267
V
A
A
S
G
L
N
T
M
L
E
G
N
G
Q
Site 17
S290
E
A
F
E
K
I
P
S
E
T
L
N
R
I
L
Site 18
T292
F
E
K
I
P
S
E
T
L
N
R
I
L
G
D
Site 19
T390
A
A
E
S
D
V
S
T
A
I
D
L
F
R
Q
Site 20
S405
A
G
L
G
N
H
L
S
G
S
E
R
L
T
L
Site 21
T424
N
S
V
F
K
D
G
T
P
P
I
D
A
H
T
Site 22
Y448
K
D
Q
L
A
S
K
Y
L
Y
H
G
Q
T
L
Site 23
Y450
Q
L
A
S
K
Y
L
Y
H
G
Q
T
L
E
T
Site 24
T454
K
Y
L
Y
H
G
Q
T
L
E
T
L
G
G
K
Site 25
T457
Y
H
G
Q
T
L
E
T
L
G
G
K
K
L
R
Site 26
Y468
K
K
L
R
V
F
V
Y
R
N
S
L
C
I
E
Site 27
Y488
A
H
D
K
R
G
R
Y
G
T
L
F
T
M
D
Site 28
T490
D
K
R
G
R
Y
G
T
L
F
T
M
D
R
V
Site 29
T493
G
R
Y
G
T
L
F
T
M
D
R
V
L
T
P
Site 30
T528
A
I
Q
S
A
G
L
T
E
T
L
N
R
E
G
Site 31
T530
Q
S
A
G
L
T
E
T
L
N
R
E
G
V
Y
Site 32
Y537
T
L
N
R
E
G
V
Y
T
V
F
A
P
T
N
Site 33
T538
L
N
R
E
G
V
Y
T
V
F
A
P
T
N
E
Site 34
S556
A
L
P
P
R
E
R
S
R
L
L
G
D
A
K
Site 35
S591
G
A
L
V
R
L
K
S
L
Q
G
D
K
L
E
Site 36
S600
Q
G
D
K
L
E
V
S
L
K
N
N
V
V
S
Site 37
S607
S
L
K
N
N
V
V
S
V
N
K
E
P
V
A
Site 38
S649
R
G
D
E
L
A
D
S
A
L
E
I
F
K
Q
Site 39
S658
L
E
I
F
K
Q
A
S
A
F
S
R
A
S
Q
Site 40
S664
A
S
A
F
S
R
A
S
Q
R
S
V
R
L
A
Site 41
S667
F
S
R
A
S
Q
R
S
V
R
L
A
P
V
Y
Site 42
Y674
S
V
R
L
A
P
V
Y
Q
K
L
L
E
R
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation