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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TGIF
Full Name:
Homeobox protein TGIF1
Alias:
5'-TG-3' interacting factor; Homeobox protein TGIF; HPE4; TALE homeobox TG-interacting factor; TGIF1
Type:
Uncharacterized protein
Mass (Da):
43013
Number AA:
401
UniProt ID:
Q15583
International Prot ID:
Isoform1 - IPI00297138
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0043565
GO:0003714
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0007275
GO:0000122
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S14
R
V
S
A
G
V
G
S
P
H
C
S
G
S
G
Site 2
S18
G
V
G
S
P
H
C
S
G
S
G
G
G
G
S
Site 3
S20
G
S
P
H
C
S
G
S
G
G
G
G
S
D
S
Site 4
S25
S
G
S
G
G
G
G
S
D
S
F
P
W
P
A
Site 5
S27
S
G
G
G
G
S
D
S
F
P
W
P
A
S
H
Site 6
S41
H
P
G
N
P
Q
C
S
F
S
T
A
F
L
A
Site 7
S43
G
N
P
Q
C
S
F
S
T
A
F
L
A
S
P
Site 8
S49
F
S
T
A
F
L
A
S
P
R
L
S
R
G
T
Site 9
T56
S
P
R
L
S
R
G
T
L
A
Y
L
P
P
A
Site 10
Y59
L
S
R
G
T
L
A
Y
L
P
P
A
P
W
S
Site 11
S66
Y
L
P
P
A
P
W
S
S
L
A
T
P
S
A
Site 12
S77
T
P
S
A
L
L
G
S
S
C
A
P
P
P
P
Site 13
S78
P
S
A
L
L
G
S
S
C
A
P
P
P
P
P
Site 14
S95
C
P
Q
P
R
A
L
S
P
E
L
G
T
K
A
Site 15
S115
H
R
W
E
L
P
R
S
P
S
Q
G
A
Q
G
Site 16
S117
W
E
L
P
R
S
P
S
Q
G
A
Q
G
P
A
Site 17
T132
P
R
R
R
L
L
E
T
M
K
G
I
V
A
A
Site 18
S140
M
K
G
I
V
A
A
S
G
S
E
T
E
D
E
Site 19
S142
G
I
V
A
A
S
G
S
E
T
E
D
E
D
S
Site 20
T144
V
A
A
S
G
S
E
T
E
D
E
D
S
M
D
Site 21
S149
S
E
T
E
D
E
D
S
M
D
I
P
L
D
L
Site 22
S157
M
D
I
P
L
D
L
S
S
S
A
G
S
G
K
Site 23
S158
D
I
P
L
D
L
S
S
S
A
G
S
G
K
R
Site 24
S159
I
P
L
D
L
S
S
S
A
G
S
G
K
R
R
Site 25
S162
D
L
S
S
S
A
G
S
G
K
R
R
R
R
G
Site 26
S175
R
G
N
L
P
K
E
S
V
Q
I
L
R
D
W
Site 27
Y184
Q
I
L
R
D
W
L
Y
E
H
R
Y
N
A
Y
Site 28
Y188
D
W
L
Y
E
H
R
Y
N
A
Y
P
S
E
Q
Site 29
Y191
Y
E
H
R
Y
N
A
Y
P
S
E
Q
E
K
A
Site 30
S201
E
Q
E
K
A
L
L
S
Q
Q
T
H
L
S
T
Site 31
T238
G
K
D
P
N
Q
F
T
I
S
R
R
G
A
K
Site 32
S240
D
P
N
Q
F
T
I
S
R
R
G
A
K
I
S
Site 33
S247
S
R
R
G
A
K
I
S
E
T
S
S
V
E
S
Site 34
T249
R
G
A
K
I
S
E
T
S
S
V
E
S
V
M
Site 35
S250
G
A
K
I
S
E
T
S
S
V
E
S
V
M
G
Site 36
S254
S
E
T
S
S
V
E
S
V
M
G
I
K
N
F
Site 37
S272
L
E
E
T
P
F
H
S
C
T
A
G
P
N
P
Site 38
T274
E
T
P
F
H
S
C
T
A
G
P
N
P
T
L
Site 39
T280
C
T
A
G
P
N
P
T
L
G
R
P
L
S
P
Site 40
S286
P
T
L
G
R
P
L
S
P
K
P
S
S
P
G
Site 41
S290
R
P
L
S
P
K
P
S
S
P
G
S
V
L
A
Site 42
S291
P
L
S
P
K
P
S
S
P
G
S
V
L
A
R
Site 43
S294
P
K
P
S
S
P
G
S
V
L
A
R
P
S
V
Site 44
T340
A
A
K
N
F
T
D
T
S
L
M
Y
P
E
D
Site 45
Y344
F
T
D
T
S
L
M
Y
P
E
D
T
C
K
S
Site 46
T348
S
L
M
Y
P
E
D
T
C
K
S
G
P
S
T
Site 47
S351
Y
P
E
D
T
C
K
S
G
P
S
T
N
T
Q
Site 48
T355
T
C
K
S
G
P
S
T
N
T
Q
S
G
L
F
Site 49
T364
T
Q
S
G
L
F
N
T
P
P
P
T
P
P
D
Site 50
T368
L
F
N
T
P
P
P
T
P
P
D
L
N
Q
D
Site 51
S377
P
D
L
N
Q
D
F
S
G
F
Q
L
L
V
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation