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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TRBP
Full Name:
RISC-loading complex subunit TARBP2
Alias:
TAR (HIV) RNA binding 2; TAR (HIV-1) RNA binding protein 2; TAR RNA binding 2; TARBP2; trans-activation responsive RNA-binding protein; TRBP1; TRBP2
Type:
RNA processing; RNA binding protein
Mass (Da):
39070
Number AA:
UniProt ID:
Q15633
International Prot ID:
IPI00386114
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016442
GO:0005634
GO:0048471
Uniprot
OncoNet
Molecular Function:
GO:0003725
GO:0042803
GO:0035197
PhosphoSite+
KinaseNET
Biological Process:
GO:0035280
GO:0050689
GO:0006469
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
S
E
E
E
Q
G
S
G
T
T
T
G
C
G
Site 2
T12
E
Q
G
S
G
T
T
T
G
C
G
L
P
S
I
Site 3
T30
L
A
A
N
P
G
K
T
P
I
S
L
L
Q
E
Site 4
S33
N
P
G
K
T
P
I
S
L
L
Q
E
Y
G
T
Site 5
Y38
P
I
S
L
L
Q
E
Y
G
T
R
I
G
K
T
Site 6
T45
Y
G
T
R
I
G
K
T
P
V
Y
D
L
L
K
Site 7
Y48
R
I
G
K
T
P
V
Y
D
L
L
K
A
E
G
Site 8
T63
Q
A
H
Q
P
N
F
T
F
R
V
T
V
G
D
Site 9
T67
P
N
F
T
F
R
V
T
V
G
D
T
S
C
T
Site 10
T71
F
R
V
T
V
G
D
T
S
C
T
G
Q
G
P
Site 11
S72
R
V
T
V
G
D
T
S
C
T
G
Q
G
P
S
Site 12
S79
S
C
T
G
Q
G
P
S
K
K
A
A
K
H
K
Site 13
S108
L
E
P
A
L
E
D
S
S
S
F
S
P
L
D
Site 14
S109
E
P
A
L
E
D
S
S
S
F
S
P
L
D
S
Site 15
S110
P
A
L
E
D
S
S
S
F
S
P
L
D
S
S
Site 16
S112
L
E
D
S
S
S
F
S
P
L
D
S
S
L
P
Site 17
S116
S
S
F
S
P
L
D
S
S
L
P
E
D
I
P
Site 18
S117
S
F
S
P
L
D
S
S
L
P
E
D
I
P
V
Site 19
S142
P
S
V
V
L
T
R
S
P
P
M
E
L
Q
P
Site 20
S152
M
E
L
Q
P
P
V
S
P
Q
Q
S
E
C
N
Site 21
S156
P
P
V
S
P
Q
Q
S
E
C
N
P
V
G
A
Site 22
Y178
K
G
W
R
L
P
E
Y
T
V
T
Q
E
S
G
Site 23
T179
G
W
R
L
P
E
Y
T
V
T
Q
E
S
G
P
Site 24
T181
R
L
P
E
Y
T
V
T
Q
E
S
G
P
A
H
Site 25
S184
E
Y
T
V
T
Q
E
S
G
P
A
H
R
K
E
Site 26
T227
K
M
L
L
R
V
H
T
V
P
L
D
A
R
D
Site 27
S246
E
P
D
D
D
H
F
S
I
G
V
G
S
R
L
Site 28
T264
R
N
R
G
P
G
C
T
W
D
S
L
R
N
S
Site 29
S267
G
P
G
C
T
W
D
S
L
R
N
S
V
G
E
Site 30
S271
T
W
D
S
L
R
N
S
V
G
E
K
I
L
S
Site 31
S299
P
A
C
C
R
V
L
S
E
L
S
E
E
Q
A
Site 32
S302
C
R
V
L
S
E
L
S
E
E
Q
A
F
H
V
Site 33
Y311
E
Q
A
F
H
V
S
Y
L
D
I
E
E
L
S
Site 34
T335
E
L
S
T
Q
P
A
T
V
C
H
G
S
A
T
Site 35
S340
P
A
T
V
C
H
G
S
A
T
T
R
E
A
A
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation