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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SF1
Full Name:
Splicing factor 1
Alias:
BBP; CW17; mammalian branch point binding protein mBBP; mZFM; SF01; splicing factor SF1; transcription factor ZFM1; ZFM1; ZFP162; zinc finger gene in MEN1 locus; zinc finger protein 162; ZNF162
Type:
RNA binding protein
Mass (Da):
68330
Number AA:
639
UniProt ID:
Q15637
International Prot ID:
IPI00386114
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005840
GO:0005681
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0003702
GO:0003714
PhosphoSite+
KinaseNET
Biological Process:
GO:0000389
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
A
T
G
A
N
A
T
P
L
D
F
P
S
K
Site 2
S14
A
T
P
L
D
F
P
S
K
K
R
K
R
S
R
Site 3
S20
P
S
K
K
R
K
R
S
R
W
N
Q
D
T
M
Site 4
T26
R
S
R
W
N
Q
D
T
M
E
Q
K
T
V
I
Site 5
T31
Q
D
T
M
E
Q
K
T
V
I
P
G
M
P
T
Site 6
Y52
T
R
E
Q
E
R
A
Y
I
V
Q
L
Q
I
E
Site 7
T62
Q
L
Q
I
E
D
L
T
R
K
L
R
T
G
D
Site 8
T67
D
L
T
R
K
L
R
T
G
D
L
G
I
P
P
Site 9
S80
P
P
N
P
E
D
R
S
P
S
P
E
P
I
Y
Site 10
S82
N
P
E
D
R
S
P
S
P
E
P
I
Y
N
S
Site 11
Y87
S
P
S
P
E
P
I
Y
N
S
E
G
K
R
L
Site 12
S89
S
P
E
P
I
Y
N
S
E
G
K
R
L
N
T
Site 13
T96
S
E
G
K
R
L
N
T
R
E
F
R
T
R
K
Site 14
T114
E
E
R
H
N
L
I
T
E
M
V
A
L
N
P
Site 15
Y129
D
F
K
P
P
A
D
Y
K
P
P
A
T
R
V
Site 16
S137
K
P
P
A
T
R
V
S
D
K
V
M
I
P
Q
Site 17
Y147
V
M
I
P
Q
D
E
Y
P
E
I
N
F
V
G
Site 18
T163
L
I
G
P
R
G
N
T
L
K
N
I
E
K
E
Site 19
S182
I
M
I
R
G
K
G
S
V
K
E
G
K
V
G
Site 20
T232
I
L
K
Q
G
I
E
T
P
E
D
Q
N
D
L
Site 21
T253
E
L
A
R
L
N
G
T
L
R
E
D
D
N
R
Site 22
S267
R
I
L
R
P
W
Q
S
S
E
T
R
S
I
T
Site 23
S268
I
L
R
P
W
Q
S
S
E
T
R
S
I
T
N
Site 24
S272
W
Q
S
S
E
T
R
S
I
T
N
T
T
V
C
Site 25
T274
S
S
E
T
R
S
I
T
N
T
T
V
C
T
K
Site 26
T276
E
T
R
S
I
T
N
T
T
V
C
T
K
C
G
Site 27
T277
T
R
S
I
T
N
T
T
V
C
T
K
C
G
G
Site 28
S290
G
G
A
G
H
I
A
S
D
C
K
F
Q
R
P
Site 29
S302
Q
R
P
G
D
P
Q
S
A
Q
D
K
A
R
M
Site 30
Y313
K
A
R
M
D
K
E
Y
L
S
L
M
A
E
L
Site 31
S315
R
M
D
K
E
Y
L
S
L
M
A
E
L
G
E
Site 32
S328
G
E
A
P
V
P
A
S
V
G
S
T
S
G
P
Site 33
T332
V
P
A
S
V
G
S
T
S
G
P
A
T
T
P
Site 34
S333
P
A
S
V
G
S
T
S
G
P
A
T
T
P
L
Site 35
T337
G
S
T
S
G
P
A
T
T
P
L
A
S
A
P
Site 36
T338
S
T
S
G
P
A
T
T
P
L
A
S
A
P
R
Site 37
S342
P
A
T
T
P
L
A
S
A
P
R
P
A
A
P
Site 38
S357
A
N
N
P
P
P
P
S
L
M
S
T
T
Q
S
Site 39
S360
P
P
P
P
S
L
M
S
T
T
Q
S
R
P
P
Site 40
T361
P
P
P
S
L
M
S
T
T
Q
S
R
P
P
W
Site 41
T362
P
P
S
L
M
S
T
T
Q
S
R
P
P
W
M
Site 42
S364
S
L
M
S
T
T
Q
S
R
P
P
W
M
N
S
Site 43
S371
S
R
P
P
W
M
N
S
G
P
S
E
S
R
P
Site 44
S374
P
W
M
N
S
G
P
S
E
S
R
P
Y
H
G
Site 45
S376
M
N
S
G
P
S
E
S
R
P
Y
H
G
M
H
Site 46
Y379
G
P
S
E
S
R
P
Y
H
G
M
H
G
G
G
Site 47
S396
G
P
G
G
G
P
H
S
F
P
H
P
L
P
S
Site 48
S403
S
F
P
H
P
L
P
S
L
T
G
G
H
G
G
Site 49
T405
P
H
P
L
P
S
L
T
G
G
H
G
G
H
P
Site 50
Y450
G
P
P
P
M
D
Q
Y
L
G
S
T
P
V
G
Site 51
S453
P
M
D
Q
Y
L
G
S
T
P
V
G
S
G
V
Site 52
T454
M
D
Q
Y
L
G
S
T
P
V
G
S
G
V
Y
Site 53
S458
L
G
S
T
P
V
G
S
G
V
Y
R
L
H
Q
Site 54
S486
P
P
P
P
P
P
P
S
G
Q
P
P
P
P
P
Site 55
S494
G
Q
P
P
P
P
P
S
G
P
L
P
P
W
Q
Site 56
S514
P
P
P
P
P
P
P
S
S
S
M
A
S
S
T
Site 57
S515
P
P
P
P
P
P
S
S
S
M
A
S
S
T
P
Site 58
S516
P
P
P
P
P
S
S
S
M
A
S
S
T
P
L
Site 59
S519
P
P
S
S
S
M
A
S
S
T
P
L
P
W
Q
Site 60
S520
P
S
S
S
M
A
S
S
T
P
L
P
W
Q
Q
Site 61
T521
S
S
S
M
A
S
S
T
P
L
P
W
Q
Q
N
Site 62
T531
P
W
Q
Q
N
T
T
T
T
T
T
S
A
G
T
Site 63
S535
N
T
T
T
T
T
T
S
A
G
T
G
S
I
P
Site 64
S540
T
T
S
A
G
T
G
S
I
P
P
W
Q
Q
Q
Site 65
S554
Q
Q
A
A
A
A
A
S
P
G
A
P
Q
M
Q
Site 66
T565
P
Q
M
Q
G
N
P
T
M
V
P
L
P
P
G
Site 67
S592
P
P
P
P
P
P
G
S
A
G
M
M
Y
A
P
Site 68
Y597
P
G
S
A
G
M
M
Y
A
P
P
P
P
P
P
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation