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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
OASL
Full Name:
59 kDa 2'-5'-oligoadenylate synthase-like protein
Alias:
Thyroid receptor-interacting protein 14;p59 OASL
Type:
Mass (Da):
59226
Number AA:
514
UniProt ID:
Q15646
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y8
M
A
L
M
Q
E
L
Y
S
T
P
A
S
R
L
Site 2
S9
A
L
M
Q
E
L
Y
S
T
P
A
S
R
L
D
Site 3
T10
L
M
Q
E
L
Y
S
T
P
A
S
R
L
D
S
Site 4
S13
E
L
Y
S
T
P
A
S
R
L
D
S
F
V
A
Site 5
S17
T
P
A
S
R
L
D
S
F
V
A
Q
W
L
Q
Site 6
T39
E
V
L
D
A
V
R
T
V
E
E
F
L
R
Q
Site 7
T74
V
G
S
F
G
N
G
T
V
L
R
S
T
R
E
Site 8
S78
G
N
G
T
V
L
R
S
T
R
E
V
E
L
V
Site 9
T79
N
G
T
V
L
R
S
T
R
E
V
E
L
V
A
Site 10
S93
A
F
L
S
C
F
H
S
F
Q
E
A
A
K
H
Site 11
S163
A
Y
R
A
L
G
P
S
L
P
N
S
Q
P
P
Site 12
S167
L
G
P
S
L
P
N
S
Q
P
P
P
E
V
Y
Site 13
S190
G
P
G
N
F
C
P
S
F
S
E
L
Q
R
N
Site 14
S192
G
N
F
C
P
S
F
S
E
L
Q
R
N
F
V
Site 15
T204
N
F
V
K
H
R
P
T
K
L
K
S
L
L
R
Site 16
S208
H
R
P
T
K
L
K
S
L
L
R
L
V
K
H
Site 17
Y217
L
R
L
V
K
H
W
Y
Q
Q
Y
V
K
A
R
Site 18
Y220
V
K
H
W
Y
Q
Q
Y
V
K
A
R
S
P
R
Site 19
S225
Q
Q
Y
V
K
A
R
S
P
R
A
N
L
P
P
Site 20
T310
I
L
D
P
A
D
P
T
L
N
V
A
E
G
Y
Site 21
S327
D
I
V
A
Q
R
A
S
Q
C
L
K
Q
D
C
Site 22
Y336
C
L
K
Q
D
C
C
Y
D
N
R
E
N
P
I
Site 23
S344
D
N
R
E
N
P
I
S
S
W
N
V
K
R
A
Site 24
T357
R
A
R
D
I
H
L
T
V
E
Q
R
G
Y
P
Site 25
Y363
L
T
V
E
Q
R
G
Y
P
D
F
N
L
I
V
Site 26
Y373
F
N
L
I
V
N
P
Y
E
P
I
R
K
V
K
Site 27
T386
V
K
E
K
I
R
R
T
R
G
Y
S
G
L
Q
Site 28
Y389
K
I
R
R
T
R
G
Y
S
G
L
Q
R
L
S
Site 29
S390
I
R
R
T
R
G
Y
S
G
L
Q
R
L
S
F
Site 30
S396
Y
S
G
L
Q
R
L
S
F
Q
V
P
G
S
E
Site 31
S402
L
S
F
Q
V
P
G
S
E
R
Q
L
L
S
S
Site 32
S408
G
S
E
R
Q
L
L
S
S
R
C
S
L
A
K
Site 33
S409
S
E
R
Q
L
L
S
S
R
C
S
L
A
K
Y
Site 34
Y416
S
R
C
S
L
A
K
Y
G
I
F
S
H
T
H
Site 35
Y492
D
W
L
G
L
G
I
Y
G
I
Q
D
S
D
T
Site 36
T499
Y
G
I
Q
D
S
D
T
L
I
L
S
K
K
K
Site 37
S503
D
S
D
T
L
I
L
S
K
K
K
G
E
A
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation