PhosphoNET

           
Protein Info 
   
Short Name:  NFKBIB
Full Name:  NF-kappa-B inhibitor beta
Alias:  IkappaBbeta; I-kappa-B-beta; IKBB; IKB-B; NF-kappaB inhibitor beta; NF-kappa-BIB; Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta; Thyroid receptor interacting protein 9; TR- interacting protein 9; TRIP9
Type:  Inhibitor protein
Mass (Da):  37771
Number AA:  356
UniProt ID:  Q15653
International Prot ID:  IPI00161119
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005829  GO:0005634   Uniprot OncoNet
Molecular Function:  GO:0004871  GO:0003713   PhosphoSite+ KinaseNET
Biological Process:  GO:0006350     Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S19DADEWCDSGLGSLGP
Site 2S23WCDSGLGSLGPDAAA
Site 3Y53WAPLVFGYVTEDGDT
Site 4T129VAERRGHTALHLACR
Site 5T160RPREAPDTYLAQGPD
Site 6Y161PREAPDTYLAQGPDR
Site 7T169LAQGPDRTPDTNHTP
Site 8T172GPDRTPDTNHTPVAL
Site 9T175RTPDTNHTPVALYPD
Site 10Y180NHTPVALYPDSDLEK
Site 11S183PVALYPDSDLEKEEE
Site 12S192LEKEEEESEEDWKLQ
Site 13Y205LQLEAENYEGHTPLH
Site 14T209AENYEGHTPLHVAVI
Site 15T239DLDKPEPTCGRSPLH
Site 16S243PEPTCGRSPLHLAVE
Site 17Y272ANPAARMYGGRTPLG
Site 18T276ARMYGGRTPLGSAML
Site 19S280GGRTPLGSAMLRPNP
Site 20S308PEGEDEKSGPCSSSS
Site 21S312DEKSGPCSSSSDSDS
Site 22S313EKSGPCSSSSDSDSG
Site 23S314KSGPCSSSSDSDSGD
Site 24S315SGPCSSSSDSDSGDE
Site 25S317PCSSSSDSDSGDEGD
Site 26S319SSSSDSDSGDEGDEY
Site 27Y326SGDEGDEYDDIVVHS
Site 28S333YDDIVVHSSRSQTRL
Site 29S336IVVHSSRSQTRLPPT
Site 30T338VHSSRSQTRLPPTPA
Site 31T343SQTRLPPTPASKPLP
Site 32S346RLPPTPASKPLPDDP
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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