KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
ZRSR1
Full Name:
U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1
Alias:
CCCH type zinc finger, RNA-binding motif and serine/arginine rich 1; MGC142159; U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related 1; U2(RNU2) small nuclear RNA auxiliary factor 1-like 1; U2AF1L1; U2AF1P; U2AF1RS1; U2AF1-RS1; U2AFBPL; U2AFL; Zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 1
Type:
Ribonucleoprotein complex protein
Mass (Da):
57643
Number AA:
479
UniProt ID:
Q15695
International Prot ID:
IPI00018952
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0030529
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0000166
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
A
A
L
E
K
M
T
F
P
K
K
M
T
F
Site 2
T14
M
T
F
P
K
K
M
T
F
P
E
K
P
S
H
Site 3
Y24
E
K
P
S
H
K
K
Y
R
A
A
L
K
K
E
Site 4
S46
E
L
A
R
L
R
D
S
G
L
S
Q
E
E
E
Site 5
S49
R
L
R
D
S
G
L
S
Q
E
E
E
E
D
T
Site 6
T56
S
Q
E
E
E
E
D
T
F
I
E
E
Q
Q
L
Site 7
T157
N
D
L
E
N
S
T
T
W
Q
N
P
E
P
P
Site 8
Y180
D
R
A
N
C
P
F
Y
S
K
T
G
A
C
R
Site 9
T200
S
R
K
H
N
F
P
T
S
S
P
T
L
L
I
Site 10
S201
R
K
H
N
F
P
T
S
S
P
T
L
L
I
K
Site 11
S202
K
H
N
F
P
T
S
S
P
T
L
L
I
K
S
Site 12
Y224
E
Q
C
R
R
D
D
Y
D
P
D
A
S
L
E
Site 13
S229
D
D
Y
D
P
D
A
S
L
E
Y
S
E
E
E
Site 14
S233
P
D
A
S
L
E
Y
S
E
E
E
T
Y
Q
Q
Site 15
T237
L
E
Y
S
E
E
E
T
Y
Q
Q
F
L
D
F
Site 16
Y238
E
Y
S
E
E
E
T
Y
Q
Q
F
L
D
F
Y
Site 17
Y245
Y
Q
Q
F
L
D
F
Y
E
D
V
L
P
E
F
Site 18
Y276
P
H
L
R
G
N
V
Y
V
Q
Y
Q
S
E
E
Site 19
Y279
R
G
N
V
Y
V
Q
Y
Q
S
E
E
E
C
Q
Site 20
Y297
S
L
F
N
G
R
W
Y
A
G
R
Q
L
Q
C
Site 21
Y352
W
E
A
N
R
D
I
Y
L
S
S
D
Q
T
G
Site 22
S354
A
N
R
D
I
Y
L
S
S
D
Q
T
G
S
S
Site 23
S355
N
R
D
I
Y
L
S
S
D
Q
T
G
S
S
F
Site 24
T358
I
Y
L
S
S
D
Q
T
G
S
S
F
G
K
N
Site 25
S360
L
S
S
D
Q
T
G
S
S
F
G
K
N
S
E
Site 26
S361
S
S
D
Q
T
G
S
S
F
G
K
N
S
E
R
Site 27
S366
G
S
S
F
G
K
N
S
E
R
R
E
K
M
G
Site 28
Y378
K
M
G
H
H
D
H
Y
Y
S
R
Q
R
G
R
Site 29
Y379
M
G
H
H
D
H
Y
Y
S
R
Q
R
G
R
R
Site 30
S389
Q
R
G
R
R
N
P
S
P
D
H
T
Y
K
R
Site 31
T393
R
N
P
S
P
D
H
T
Y
K
R
N
G
E
S
Site 32
Y394
N
P
S
P
D
H
T
Y
K
R
N
G
E
S
E
Site 33
S400
T
Y
K
R
N
G
E
S
E
R
K
K
S
S
H
Site 34
S405
G
E
S
E
R
K
K
S
S
H
R
G
K
K
S
Site 35
S406
E
S
E
R
K
K
S
S
H
R
G
K
K
S
H
Site 36
S412
S
S
H
R
G
K
K
S
H
K
R
T
S
K
S
Site 37
T416
G
K
K
S
H
K
R
T
S
K
S
R
E
R
H
Site 38
S417
K
K
S
H
K
R
T
S
K
S
R
E
R
H
N
Site 39
S419
S
H
K
R
T
S
K
S
R
E
R
H
N
S
P
Site 40
S425
K
S
R
E
R
H
N
S
P
S
R
G
R
N
R
Site 41
S427
R
E
R
H
N
S
P
S
R
G
R
N
R
H
R
Site 42
S435
R
G
R
N
R
H
R
S
W
D
Q
G
R
R
S
Site 43
S442
S
W
D
Q
G
R
R
S
Q
S
R
R
S
H
R
Site 44
S444
D
Q
G
R
R
S
Q
S
R
R
S
H
R
S
R
Site 45
S447
R
R
S
Q
S
R
R
S
H
R
S
R
S
Q
S
Site 46
S450
Q
S
R
R
S
H
R
S
R
S
Q
S
S
S
R
Site 47
S452
R
R
S
H
R
S
R
S
Q
S
S
S
R
C
R
Site 48
S454
S
H
R
S
R
S
Q
S
S
S
R
C
R
S
R
Site 49
S455
H
R
S
R
S
Q
S
S
S
R
C
R
S
R
G
Site 50
S456
R
S
R
S
Q
S
S
S
R
C
R
S
R
G
R
Site 51
S460
Q
S
S
S
R
C
R
S
R
G
R
R
K
S
G
Site 52
S466
R
S
R
G
R
R
K
S
G
N
R
D
R
T
V
Site 53
T472
K
S
G
N
R
D
R
T
V
Q
S
P
Q
S
K
Site 54
S475
N
R
D
R
T
V
Q
S
P
Q
S
K
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation