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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZRSR2
Full Name:
U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2
Alias:
CCCH type zinc finger, RNA-binding motif and serine/arginine rich 2; MGC142014; MGC142040; Renal carcinoma antigen NY-REN-20; U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related 2; U2(RNU2) small nuclear RNA auxiliary factor 1-like 2; U2AF1L2; U2AF1RS2; U2AF1-RS2; U2AFM; URP; Zinc finger (CCCH type) RNA-binding motif and serine/arginine rich 2; Zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2
Type:
Mass (Da):
58045
Number AA:
482
UniProt ID:
Q15696
International Prot ID:
IPI00018954
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005689
GO:0005681
GO:0005689
Uniprot
OncoNet
Molecular Function:
GO:0003723
GO:0000166
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0008380
GO:0006396
GO:0008152
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
A
A
P
E
K
M
T
F
P
E
K
P
S
H
Site 2
Y18
E
K
P
S
H
K
K
Y
R
A
A
L
K
K
E
Site 3
S40
E
L
A
R
L
R
D
S
G
L
S
Q
K
E
E
Site 4
S43
R
L
R
D
S
G
L
S
Q
K
E
E
E
E
D
Site 5
T51
Q
K
E
E
E
E
D
T
F
I
E
E
Q
Q
L
Site 6
T152
N
E
L
E
N
G
T
T
W
Q
N
P
E
P
P
Site 7
Y175
D
R
A
N
C
P
F
Y
S
K
T
G
A
C
R
Site 8
T195
S
R
K
H
N
F
P
T
S
S
P
T
L
L
I
Site 9
S196
R
K
H
N
F
P
T
S
S
P
T
L
L
I
K
Site 10
S197
K
H
N
F
P
T
S
S
P
T
L
L
I
K
S
Site 11
Y219
E
Q
C
R
R
D
D
Y
D
P
D
A
S
L
E
Site 12
S224
D
D
Y
D
P
D
A
S
L
E
Y
S
E
E
E
Site 13
S228
P
D
A
S
L
E
Y
S
E
E
E
T
Y
Q
Q
Site 14
T232
L
E
Y
S
E
E
E
T
Y
Q
Q
F
L
D
F
Site 15
Y233
E
Y
S
E
E
E
T
Y
Q
Q
F
L
D
F
Y
Site 16
Y240
Y
Q
Q
F
L
D
F
Y
E
D
V
L
P
E
F
Site 17
Y271
P
H
L
R
G
N
V
Y
V
Q
Y
Q
S
E
E
Site 18
Y274
R
G
N
V
Y
V
Q
Y
Q
S
E
E
E
C
Q
Site 19
Y292
S
L
F
N
G
R
W
Y
A
G
R
Q
L
Q
C
Site 20
Y347
W
E
A
N
R
D
I
Y
L
S
P
D
R
T
G
Site 21
S349
A
N
R
D
I
Y
L
S
P
D
R
T
G
S
S
Site 22
T353
I
Y
L
S
P
D
R
T
G
S
S
F
G
K
N
Site 23
S355
L
S
P
D
R
T
G
S
S
F
G
K
N
S
E
Site 24
S356
S
P
D
R
T
G
S
S
F
G
K
N
S
E
R
Site 25
S361
G
S
S
F
G
K
N
S
E
R
R
E
R
M
G
Site 26
Y373
R
M
G
H
H
D
D
Y
Y
S
R
L
R
G
R
Site 27
Y374
M
G
H
H
D
D
Y
Y
S
R
L
R
G
R
R
Site 28
S375
G
H
H
D
D
Y
Y
S
R
L
R
G
R
R
N
Site 29
S384
L
R
G
R
R
N
P
S
P
D
H
S
Y
K
R
Site 30
S388
R
N
P
S
P
D
H
S
Y
K
R
N
G
E
S
Site 31
Y389
N
P
S
P
D
H
S
Y
K
R
N
G
E
S
E
Site 32
S395
S
Y
K
R
N
G
E
S
E
R
K
S
S
R
H
Site 33
S399
N
G
E
S
E
R
K
S
S
R
H
R
G
K
K
Site 34
S400
G
E
S
E
R
K
S
S
R
H
R
G
K
K
S
Site 35
S407
S
R
H
R
G
K
K
S
H
K
R
T
S
K
S
Site 36
T411
G
K
K
S
H
K
R
T
S
K
S
R
E
R
H
Site 37
S412
K
K
S
H
K
R
T
S
K
S
R
E
R
H
N
Site 38
S414
S
H
K
R
T
S
K
S
R
E
R
H
N
S
R
Site 39
S420
K
S
R
E
R
H
N
S
R
S
R
G
R
N
R
Site 40
S422
R
E
R
H
N
S
R
S
R
G
R
N
R
D
R
Site 41
S430
R
G
R
N
R
D
R
S
R
D
R
S
R
G
R
Site 42
S434
R
D
R
S
R
D
R
S
R
G
R
G
S
R
S
Site 43
S439
D
R
S
R
G
R
G
S
R
S
R
S
R
S
R
Site 44
S441
S
R
G
R
G
S
R
S
R
S
R
S
R
S
R
Site 45
S443
G
R
G
S
R
S
R
S
R
S
R
S
R
R
S
Site 46
S445
G
S
R
S
R
S
R
S
R
S
R
R
S
R
R
Site 47
S447
R
S
R
S
R
S
R
S
R
R
S
R
R
S
R
Site 48
S450
S
R
S
R
S
R
R
S
R
R
S
R
S
Q
S
Site 49
S453
R
S
R
R
S
R
R
S
R
S
Q
S
S
S
R
Site 50
S455
R
R
S
R
R
S
R
S
Q
S
S
S
R
S
R
Site 51
S457
S
R
R
S
R
S
Q
S
S
S
R
S
R
S
R
Site 52
S458
R
R
S
R
S
Q
S
S
S
R
S
R
S
R
G
Site 53
S459
R
S
R
S
Q
S
S
S
R
S
R
S
R
G
R
Site 54
S461
R
S
Q
S
S
S
R
S
R
S
R
G
R
R
R
Site 55
S463
Q
S
S
S
R
S
R
S
R
G
R
R
R
S
G
Site 56
S469
R
S
R
G
R
R
R
S
G
N
R
D
R
T
V
Site 57
T475
R
S
G
N
R
D
R
T
V
Q
S
P
K
S
K
Site 58
S478
N
R
D
R
T
V
Q
S
P
K
S
K
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation