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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF174
Full Name:
Zinc finger protein 174
Alias:
AW-1;Zinc finger and SCAN domain-containing protein 8
Type:
Transcription factor
Mass (Da):
46455
Number AA:
407
UniProt ID:
Q15697
International Prot ID:
IPI00018955
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005856
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0003700
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0000122
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
A
K
M
E
I
T
L
S
S
N
T
E
A
S
S
Site 2
Y54
Q
S
F
R
R
F
C
Y
Q
E
V
S
G
P
Q
Site 3
S65
S
G
P
Q
E
A
L
S
Q
L
R
Q
L
C
R
Site 4
S114
R
H
R
C
P
M
S
S
K
E
I
V
T
L
V
Site 5
S128
V
E
D
F
H
R
A
S
K
K
P
K
Q
W
V
Site 6
S151
V
L
L
E
K
T
G
S
Q
L
G
E
Q
E
L
Site 7
T165
L
P
D
F
Q
P
Q
T
P
R
R
D
L
R
E
Site 8
S173
P
R
R
D
L
R
E
S
S
P
A
E
P
S
Q
Site 9
S174
R
R
D
L
R
E
S
S
P
A
E
P
S
Q
A
Site 10
S179
E
S
S
P
A
E
P
S
Q
A
G
A
Y
D
R
Site 11
Y184
E
P
S
Q
A
G
A
Y
D
R
L
S
P
H
H
Site 12
S188
A
G
A
Y
D
R
L
S
P
H
H
W
E
K
S
Site 13
S195
S
P
H
H
W
E
K
S
P
L
L
Q
E
P
T
Site 14
T202
S
P
L
L
Q
E
P
T
P
K
L
A
G
T
E
Site 15
T208
P
T
P
K
L
A
G
T
E
A
P
R
M
R
S
Site 16
S215
T
E
A
P
R
M
R
S
D
N
K
E
N
P
Q
Site 17
S235
G
A
K
P
C
A
V
S
A
G
R
S
K
G
N
Site 18
S239
C
A
V
S
A
G
R
S
K
G
N
G
L
Q
N
Site 19
S255
E
P
R
G
A
N
M
S
E
P
R
L
S
R
R
Site 20
S260
N
M
S
E
P
R
L
S
R
R
Q
V
S
S
P
Site 21
S265
R
L
S
R
R
Q
V
S
S
P
N
A
Q
K
P
Site 22
S266
L
S
R
R
Q
V
S
S
P
N
A
Q
K
P
F
Site 23
Y276
A
Q
K
P
F
A
H
Y
Q
R
H
C
R
V
E
Site 24
Y284
Q
R
H
C
R
V
E
Y
I
S
S
P
L
K
S
Site 25
S286
H
C
R
V
E
Y
I
S
S
P
L
K
S
H
P
Site 26
S287
C
R
V
E
Y
I
S
S
P
L
K
S
H
P
L
Site 27
S291
Y
I
S
S
P
L
K
S
H
P
L
R
E
L
K
Site 28
S300
P
L
R
E
L
K
K
S
K
G
G
K
R
S
L
Site 29
S306
K
S
K
G
G
K
R
S
L
S
N
R
L
Q
H
Site 30
S308
K
G
G
K
R
S
L
S
N
R
L
Q
H
L
G
Site 31
S321
L
G
H
Q
P
T
R
S
A
K
K
P
Y
K
C
Site 32
T336
D
D
C
G
K
S
F
T
W
N
S
E
L
K
R
Site 33
S339
G
K
S
F
T
W
N
S
E
L
K
R
H
K
R
Site 34
T349
K
R
H
K
R
V
H
T
G
E
R
P
Y
T
C
Site 35
Y354
V
H
T
G
E
R
P
Y
T
C
G
E
C
G
N
Site 36
T355
H
T
G
E
R
P
Y
T
C
G
E
C
G
N
C
Site 37
S367
G
N
C
F
G
R
Q
S
T
L
K
L
H
Q
R
Site 38
T368
N
C
F
G
R
Q
S
T
L
K
L
H
Q
R
I
Site 39
T377
K
L
H
Q
R
I
H
T
G
E
K
P
Y
Q
C
Site 40
Y382
I
H
T
G
E
K
P
Y
Q
C
G
Q
C
G
K
Site 41
S390
Q
C
G
Q
C
G
K
S
F
R
Q
S
S
N
L
Site 42
S395
G
K
S
F
R
Q
S
S
N
L
H
Q
H
H
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation