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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ALX1
Full Name:
ALX homeobox protein 1
Alias:
ALX homeobox 1; CART1; CART-1; Cartilage homeoprotein 1
Type:
Mass (Da):
36961
Number AA:
326
UniProt ID:
Q15699
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
Uniprot
OncoNet
Molecular Function:
GO:0003714
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0007420
GO:0001502
GO:0000122
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
S
E
K
F
A
L
K
S
P
P
S
K
N
S
D
Site 2
S15
F
A
L
K
S
P
P
S
K
N
S
D
F
Y
M
Site 3
S18
K
S
P
P
S
K
N
S
D
F
Y
M
G
A
G
Site 4
Y21
P
S
K
N
S
D
F
Y
M
G
A
G
G
P
L
Site 5
T34
P
L
E
H
V
M
E
T
L
D
N
E
S
F
Y
Site 6
S39
M
E
T
L
D
N
E
S
F
Y
S
K
A
S
A
Site 7
Y41
T
L
D
N
E
S
F
Y
S
K
A
S
A
G
K
Site 8
S42
L
D
N
E
S
F
Y
S
K
A
S
A
G
K
C
Site 9
S45
E
S
F
Y
S
K
A
S
A
G
K
C
V
Q
A
Site 10
S69
H
V
R
L
E
R
T
S
P
C
Q
D
S
S
V
Site 11
S75
T
S
P
C
Q
D
S
S
V
N
Y
G
I
T
K
Site 12
Y78
C
Q
D
S
S
V
N
Y
G
I
T
K
V
E
G
Site 13
S101
R
A
M
D
N
C
N
S
L
R
M
S
P
V
K
Site 14
S105
N
C
N
S
L
R
M
S
P
V
K
G
M
Q
E
Site 15
S125
E
L
G
D
K
C
D
S
N
V
S
S
S
K
K
Site 16
S129
K
C
D
S
N
V
S
S
S
K
K
R
R
H
R
Site 17
S130
C
D
S
N
V
S
S
S
K
K
R
R
H
R
T
Site 18
T137
S
K
K
R
R
H
R
T
T
F
T
S
L
Q
L
Site 19
T138
K
K
R
R
H
R
T
T
F
T
S
L
Q
L
E
Site 20
S141
R
H
R
T
T
F
T
S
L
Q
L
E
E
L
E
Site 21
T154
L
E
K
V
F
Q
K
T
H
Y
P
D
V
Y
V
Site 22
Y156
K
V
F
Q
K
T
H
Y
P
D
V
Y
V
R
E
Site 23
Y160
K
T
H
Y
P
D
V
Y
V
R
E
Q
L
A
L
Site 24
Y193
K
W
R
K
R
E
R
Y
G
Q
I
Q
Q
A
K
Site 25
Y207
K
S
H
F
A
A
T
Y
D
I
S
V
L
P
R
Site 26
S210
F
A
A
T
Y
D
I
S
V
L
P
R
T
D
S
Site 27
T215
D
I
S
V
L
P
R
T
D
S
Y
P
Q
I
Q
Site 28
S217
S
V
L
P
R
T
D
S
Y
P
Q
I
Q
N
N
Site 29
Y218
V
L
P
R
T
D
S
Y
P
Q
I
Q
N
N
L
Site 30
S238
S
G
G
S
V
V
T
S
C
M
L
P
R
D
T
Site 31
T245
S
C
M
L
P
R
D
T
S
S
C
M
T
P
Y
Site 32
S246
C
M
L
P
R
D
T
S
S
C
M
T
P
Y
S
Site 33
S247
M
L
P
R
D
T
S
S
C
M
T
P
Y
S
H
Site 34
T250
R
D
T
S
S
C
M
T
P
Y
S
H
S
P
R
Site 35
S253
S
S
C
M
T
P
Y
S
H
S
P
R
T
D
S
Site 36
S255
C
M
T
P
Y
S
H
S
P
R
T
D
S
S
Y
Site 37
T258
P
Y
S
H
S
P
R
T
D
S
S
Y
T
G
F
Site 38
S260
S
H
S
P
R
T
D
S
S
Y
T
G
F
S
N
Site 39
S261
H
S
P
R
T
D
S
S
Y
T
G
F
S
N
H
Site 40
Y262
S
P
R
T
D
S
S
Y
T
G
F
S
N
H
Q
Site 41
S266
D
S
S
Y
T
G
F
S
N
H
Q
N
Q
F
S
Site 42
S305
K
P
E
F
E
R
R
S
S
S
I
A
V
L
R
Site 43
S306
P
E
F
E
R
R
S
S
S
I
A
V
L
R
M
Site 44
S307
E
F
E
R
R
S
S
S
I
A
V
L
R
M
K
Site 45
T319
R
M
K
A
K
E
H
T
A
N
I
S
W
A
M
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation