PhosphoNET

           
Protein Info 
   
Short Name:  SMAD1
Full Name:  Mothers against decapentaplegic homolog 1
Alias:  SMAD 1
Type:  Transcription protein
Mass (Da):  52260
Number AA:  465
UniProt ID:  Q15797
International Prot ID:  IPI00019549
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005622  GO:0005634  GO:0005654 Uniprot OncoNet
Molecular Function:  GO:0003676  GO:0003677  GO:0003700 PhosphoSite+ KinaseNET
Biological Process:  GO:0000003  GO:0000165  GO:0006139 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S11TSLFSFTSPAVKRLL
Site 2S56EELEKALSCPGQPSN
Site 3S62LSCPGQPSNCVTIPR
Site 4T66GQPSNCVTIPRSLDG
Site 5S70NCVTIPRSLDGRLQV
Site 6S78LDGRLQVSHRKGLPH
Site 7Y88KGLPHVIYCRVWRWP
Site 8Y127VCINPYHYKRVESPV
Site 9S132YHYKRVESPVLPPVL
Site 10S144PVLVPRHSEYNPQHS
Site 11Y146LVPRHSEYNPQHSLL
Site 12T171PHMPLNATFPDSFQQ
Site 13S175LNATFPDSFQQPNSH
Site 14S181DSFQQPNSHPFPHSP
Site 15S187NSHPFPHSPNSSYPN
Site 16S190PFPHSPNSSYPNSPG
Site 17S191FPHSPNSSYPNSPGS
Site 18Y192PHSPNSSYPNSPGSS
Site 19S195PNSSYPNSPGSSSST
Site 20S198SYPNSPGSSSSTYPH
Site 21S199YPNSPGSSSSTYPHS
Site 22S200PNSPGSSSSTYPHSP
Site 23S201NSPGSSSSTYPHSPT
Site 24T202SPGSSSSTYPHSPTS
Site 25Y203PGSSSSTYPHSPTSS
Site 26S206SSSTYPHSPTSSDPG
Site 27T208STYPHSPTSSDPGSP
Site 28S209TYPHSPTSSDPGSPF
Site 29S210YPHSPTSSDPGSPFQ
Site 30S214PTSSDPGSPFQMPAD
Site 31T222PFQMPADTPPPAYLP
Site 32Y227ADTPPPAYLPPEDPM
Site 33T235LPPEDPMTQDGSQPM
Site 34S239DPMTQDGSQPMDTNM
Site 35T244DGSQPMDTNMMAPPL
Site 36Y265GDVQAVAYEEPKHWC
Site 37T300SVLVDGFTDPSNNKN
Site 38S315RFCLGLLSNVNRNST
Site 39S321LSNVNRNSTIENTRR
Site 40T322SNVNRNSTIENTRRH
Site 41T326RNSTIENTRRHIGKG
Site 42S351YAECLSDSSIFVQSR
Site 43S352AECLSDSSIFVQSRN
Site 44T370HHGFHPTTVCKIPSG
Site 45T402SVNHGFETVYELTKM
Site 46Y404NHGFETVYELTKMCT
Site 47Y424VKGWGAEYHRQDVTS
Site 48T430EYHRQDVTSTPCWIE
Site 49T452QWLDKVLTQMGSPHN
Site 50S456KVLTQMGSPHNPISS
Site 51S462GSPHNPISSVS____
Site 52S463SPHNPISSVS_____
Site 53S465HNPISSVS_______
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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